
Accra Hearts of Oak Sporting Club, commonly referred to as Hearts of Oak or just Hearts is a professional sports club based in Accra, Ghana. The club competes in the Ghana Premier League, the Premier division on the Ghanaian football pyramid. The Ohene Djan Sports Stadium is their home grounds where they play their home games. Hearts has won the Premier League twenty times, the FA cup a record ten times, the President's Cup twice, and the CAF African Champions League and the CAF Confederations Cup each once. Hearts of Oak was also ranked 8th football club in the world in the year 2000 when the club dominated most of the continent sporting activities.

Aduana Stars Football Club is a professional football club, based in Dormaa Ahenkro, Bono Region, Ghana. The club is competing in the Ghanaian Premier League. It made history by winning the Ghana Premier League at their first attempt with 53 points. It became the ninth club to win the Ghana Premier League in its 54-year-old history.

Asante Kotoko Sporting Club, also known as Asante Kotoko, is a professional football club from Kumasi, Ashanti Region in Ghana West Africa. Their home grounds is based at Baba Yara Stadium in Amakom, Kumasi. They compete in the Ghanaian Premier League. They have been champions of the Ghana Premier League a record 24 times, have won the CAF Champions League twice and were adjudged the African club of the century by International Football Federation of History and Statistics. They are also called the Porcupine Warriors.

Ashanti Gold Sporting Club popularly known as AshGold is a Ghanaian football team based in the gold mining town of Obuasi, south of Kumasi the capital of Ashanti Region. The club are currently competing in the Ghana Premier League.

Founded in 1995, Berekum Arsenal Football Club is a Ghanaian football club based in Berekum in the Bono region of Ghana, about 30mins drive west from Sunyani. They are a member of the Division One League.

Berekum Chelsea Football Club is a Ghanaian professional football club based in Berekum, Bono Region, previously known as Bechem Chelsea Football Club. They compete in the Ghanaian top-flight league called the First Capital Premier League.

Dreams Football Club is a Ghanaian professional football club based in the Greater Accra Region, Ghana. The club is competing in the Ghanaian Premier League.

Elmina Sharks F.C. is a football club from Ghana based in Elmina, Central Region. The club is competing in the 2018 Ghanaian Premier League. Home games are played at Nduom Sports Stadium.

Heart of Lions Football Club is a Ghanaian professional football club based in Kpandu, Volta. The club competed in the Glo Premier League, being relegated in 2015.

Karela United FC is a Ghanaian professional football club based in Aiyinase, Ellembele District, Western Region. The club competed in the 2019 Ghanaian Normalisation Cup Competition. and was runners up Karela plays their home matches at the CAM Park.

King Faisal Babes Football Club is a professional football club in Kumasi, Ashanti, Ghana. The club competes in the Glo Premier League. They were represented at the FIFA World Cup 2006 by left-back Habib Mohamed, who was playing for Ghana national team. King Faisal Babies were relegated at the end of the 2010–11 Glo Premier League season and played in the Poly Tank Division One League in the 2011–12 season. Then were re-promoted to the 2012–13 Glo Premier League season. The club have never won the Ghana Premier League.

Legon Cities FC is a football club from Ghana currently based in Accra, Greater Accra. The club won the 2016 Ghanaian Premier League.

Liberty Professionals Football Club is a Ghanaian professional football club based in Dansoman, Accra.

Real Tamale United, often abbreviated as RTU, is a football club based in Tamale, Northern Region of Ghana. They are competing in the Ghana Division One League, after being relegated to the second tier in the 2013–14 Ghana Football Leagues#Division One League. Their home stadium is Tamale Stadium They moved there from the Kaladan Park after the 2008 African Cup of Nations.

Techiman City FC is a football club in Techiman, Ghana.

Techiman Eleven Wonders FC are a Ghanaian football club from Techiman currently playing in the Ghana Premier League. They play televised home games in the Obuasi Len Clay Sports Stadium in Obuasi.

Tema City FC, commonly referred to as Tema City, is a Ghanaian football club based in Tema, Greater Accra. They compete in the Division Two League in Ghana.

Tema Youth Football Club is a Ghanaian professional football club based in Tema, Greater Accra. The club competed in the 2017 Ghanaian Premier League, but got relegated at the end of the season.