2019 Italian Athletics Indoor Championships was the 50th edition of the Italian Athletics Indoor Championships and were held in Ancona.

The 2019 Euro Beach Soccer League (EBSL) was the 22nd edition of the Euro Beach Soccer League, the annual, premier competition in European beach soccer contested between men's national teams. It was organised by Beach Soccer Worldwide (BSWW), in a league and play-off format.

Italy is scheduled to compete at the 2019 European Games, in Minsk, Belarus from 21 to 30 June 2019. Italy has previously competed at the 2015 European Games in Baku, Azerbaijan, where it won 47 medals, including ten golds.

The 2019 European Shooting Championships were held in Bologna and Tolmezzo, Italy from 12 to 23 September 2019.

The 30th women's Giro d'Italia, or Giro Rosa, was held from 5 to 14 July 2019. Raced over ten stages, it was considered the most prestigious stage race of the women's calendar. The defending champion, Annemiek van Vleuten, won the race.

The 2019 Giro d'Italia was a three-week Grand Tour cycling stage race organised by RCS Sport that took place mainly in Italy, between 11 May and 2 June 2019. The race was the 102nd edition of the Giro d'Italia and was the first Grand Tour of the 2019 cycling season. The race started with an individual time trial in Bologna, and finished with another time-trial in Verona. The race was won by Richard Carapaz, who became the first Ecuadorian rider to win the Giro d'Italia. Italian Vincenzo Nibali finished 2nd, with Slovenian rider Primož Roglič in 3rd place. Carapaz also became the second South American rider to win the Giro, after Nairo Quintana in 2014.

The 2019 International Swimming League was the inaugural edition of the International Swimming League, a professional swimming league, established in 2019. It comprised eight teams composed of both women and men. The league consisted of seven short course swimming meets which took place in seven cities around the world.

Italy competed at the 2019 European Athletics Indoor Championships in Glasgow, United Kingdom, from 1 to 3 March 2019 with 27 athletes.

The 2019 Milan–San Remo was the 110th edition of the Milan–San Remo one-day Italian road cycling race that took place on 23 March 2019. It was the eighth event of the 2019 UCI World Tour, and was the first Monument of the year. The race was won in the sprint by Julian Alaphilippe before Oliver Naesen and the winner of the 2017 race Michal Kwiatkowski.

Italy competed at the 2019 Military World Games held in Wuhan, China from 18 to 27 October 2019.

The 2019 Rally Italia Sardegna was a motor racing event for rally cars that was held over four days between 13 and 16 June 2019. It marked the sixteenth running of Rally Italia Sardegna and was the eighth round of the 2019 World Rally Championship, World Rally Championship-2 and the newly-created WRC-2 Pro class. It was also the third round of the Junior World Rally Championship. The 2019 event was based in Alghero in Sardinia, and was contested over nineteen special stages with a total a competitive distance of 310.52 km (192.95 mi).

The 13th edition of the Strade Bianche was held on 9 March 2019. Starting and finishing in Siena, Italy, it was the fifth event of the 2019 UCI World Tour. It was won by Julian Alaphilippe, followed by Jakob Fuglsang. Wout van Aert was third.

The fifth edition of the Strade Bianche Donne was held on 9 March 2019. Dutch rider Annemiek van Vleuten won the race after breaking clear on the final gravel sector. Denmark's Annika Langvad finished second, Poland's Kasia Niewiadoma third. Starting and finishing in Siena, Italy, it was the opening event of the 2019 UCI Women's World Tour.

Italy participated at the 2019 Summer Universiade in Naples, Italy from 3 to 14 July 2019.

The 2019 Trofeo Alfredo Binda-Comune di Cittiglio was the 21st running of the Trofeo Alfredo Binda, a women's cycling race in Italy. It was the third event of the 2019 UCI Women's World Tour season and was held on 24 March 2019. The race started in Gavirate and finished in Cittiglio, on the outskirts of Lago Maggiore in Northwest Italy.

The 2019 Summer Universiade, the XXX Summer Universiade was held in Naples, Italy, between 3 and 14 July 2019.

The 2019 Winter Deaflympics, officially known as the 19th Winter Deaflympics or XIX Winter Deaflympics, was the 19th edition of the Winter Deaflympics, and took place between the 12th-21st of December in Sondrio Province in Northern Italy. The opening ceremony was held in Sondrio on 12 December and curling competition began a day prior to the start of the Winter Deaflympics. Sporting events apart from curling commenced on 13 December.

Italy competed at the 2019 Winter Deaflympics held between 12 and 21 December 2019 in Sondrio Province in Northern Italy. Alpine skier Giacomo Pierbon won gold medals in all five men's alpine skiing events which meant that the country finished in 2nd place in the medal table with a total of five gold medals and two bronze medals.

Italy competed at the 2019 World Aquatics Championships in Gwangju, South Korea from 12 to 28 July.

Italy competed at the inaugural World Beach Games in Doha, Qatar from 12 to 16 October 2019. In total, athletes representing Italy won four gold medals, one silver medal and one bronze medal. The country finished in 9th place in the medal table.

Italy competed at the 2019 IAAF World Relays in Yokohama, Japan, from 11–19 May 2019.

Italy competed at the 2019 World Athletics Championships in Doha, Qatar, from 27 September to 6 October 2019.