
The Africa Cup is an annual rugby union tournament involving African nations, organised by Rugby Africa. The tournament was first held in 2000, and has since been contested on an annual basis. Prior to being renamed the Africa Cup in 2006, the tournament was known as the CAR Top 9 and CAR Top 10.

The African Southern Region Half Marathon Championships is an annual international long-distance road running competition over the half marathon distance (21.1 km) between Southern African nations, organised by the Confederation of African Athletics (CAA). It was established in 2000, and is one of three regional half marathon championships organised by the CAA, alongside the North and East African Half Marathon Championships.

The Alfred Dunhill Championship is a men's professional golf tournament which is played in South Africa. It is part of the Southern African Sunshine Tour and is one of several events in South Africa that are co-sanctioned by the more prestigious European Tour.
The Bogotá International Half Marathon, or mmB as it is traditionally known, is an annual road running competition over a half marathon distance taking place in Bogotá, Colombia in late July or early August, first held in 2000. The competition features both elite and popular sections within the half marathon and 10K races. Around 45,000 runners take part in the competition's events each year.
The Brazilian National Road Race Championships have been held since 2000.
The Brazilian National Time Trial Championships have been held since 2000.

The Bulgarian National Road Race Championships are held annually to decide the cycling champions in the road race discipline, across various categories. The championship was first held in 2000.

The Bulgarian National Time Trial Championships are held annually to decide the cycling champions in the time trial discipline, across various categories. The championship was first held in 2000.

The Canberra 400, also known as the GMC Canberra 400 or Stegbar Canberra 400 for sponsorship reasons, was a V8 Supercar event on the Canberra Street Circuit in Canberra, Australian Capital Territory, Australia. The race only had a short life, running from 2000 to 2002 over the Queen's Birthday holiday weekend in June.

The Commonwealth Youth Games (CYG) is an international multi-sport event organized by the Commonwealth Games Federation. The games are held every four years with the current Commonwealth Games format. The first version was held in Edinburgh, Scotland from 10 to 14 August 2000. The age limitation of the athletes is 14 to 18.

The Michael Davitt Shield is a Scottish Gaelic Football pre-season tournament founded in 2001. The competition takes place in the April of each season. The trophy is named after Irish Republican activist and founder of the Irish National Land League, Michael Davitt. Glaschu Gaels were the inaugural champions in 2000 and have won the competition a record four times. On 30 April 2009, Tir Conaill Harps won the competition for the second time in their history after overcoming record winners and city rivals Glaschu Gaels 1-10 to 1-06 in Coatbridge.

The DGM Barbados Open was a senior men's professional golf tournament played on the Caribbean island state of Barbados, played annually from 2000 to 2009. It was an early season event on the European Senior Tour and generally the only regular event on the tour that took place in the Americas. It was hosted by the Royal Westmoreland Golf Club, Saint James, Barbados.

The East African Half Marathon Championships was an international half marathon competition among athletes from East Africa. The competition was the first dedicated road running championship. The event was contiguous with other regional competitions in the sport of athletics, including the East African Athletics Championships and the East African Cross Country Championships. An East African Marathon Championships was also briefly held during this period, having only one outing in 2002.

The European Seniors Match Play Championship was a senior men's professional match play golf tournament played on the European Seniors Tour from 2000 to 2004. In 2000 and 2001 it was held at Penina Golf, Portimão, on the Algarve, Portugal, while from 2002 to 2004 it was held at Flamingos Golf, Marbella, Málaga, Spain. Prize money totalled £100,000.

The Fergana Challenger is a professional tennis tournament played on outdoor hard courts. It is currently part of the Association of Tennis Professionals (ATP) Challenger Tour and the ITF Women's Circuit. It has been held annually at the Istiklol Tennis Club in Fergana, Uzbekistan, since 2000.
The Florida College Hockey Classic was a college Division I men's ice hockey tournament played annually between 2000 and 2016 in the week between Christmas and New Years at the Germain Arena in Estero, Florida, United States.

The Formula Sun Grand Prix (FSGP) is an annual solar-car race that takes place on closed-loop race tracks. In the race, teams from colleges and universities throughout North America design, build, test, and race solar-powered vehicles.

The Greek National Road Race Championships have been held since 2000.

The Greek National Time Trial Championships have been held since 2000.

The Green Bay Marathon is an annual race event that takes place on the 3rd week of May in Green Bay, Wisconsin.

The Japan Golf Tour Championship is a professional golf tournament on the Japan Golf Tour. Founded in 2000, it is one of the four major championships on the tour.
The KDI Office Technology 200 was an annual 200-mile (321.869 km) NASCAR Gander RV & Outdoors Truck Series race held at the Dover International Speedway in Dover, Delaware. The race was the only race to be shown on tape delay during the past several seasons, but was televised live from 2012 to 2020.
The Kentucky Indy 300 was an IndyCar Series race held at Kentucky Speedway in Sparta, Kentucky.

Legs for Literacy is an annual marathon held in Moncton, New Brunswick, Canada in October. The race day also includes a half marathon, 10 km, and 5 km race.

Marathon des Dunes is a sporting event that takes places in the Sahara desert in Algeria. It was first held in 2000 and its exact location and course changes from year to year.

The Maratona di Sant'Antonio is an annual road running competition which takes place in April in Padua, Italy. The event features a full marathon race (42.195 km), a half marathon, and a range of shorter fun run events for amateurs. The competition is named in honour of Anthony of Padua, a 13th-century saint who died in the city.

The Milano City Marathon is a marathon race held every April in Milan, Italy. It was first organised in 2000 by the Milano City Marathon Club and the first nine editions were held in November.

The Mountain West Conference Women's Basketball Tournament is the conference championship tournament in women's basketball for the Mountain West Conference. It is a single-elimination tournament involving all of the 11 league schools, and seeding is based on regular-season records with head-to-head match-up as a tie-breaker. The winner receives the conference's automatic bid to the NCAA women's basketball tournament.

The New Zealand Sevens is an annual rugby sevens tournament currently held at Waikato Stadium in Hamilton, New Zealand. For the first eighteen years of its history the event was held in Wellington. The event is the third on the World Rugby Sevens Series circuit and is generally held in late January or early February.

The NextEra Energy 250 is the first race of the NASCAR Camping World Truck Series season at Daytona International Speedway and as of 2004 has been held under the lights. It is the Truck Series event of Speedweeks – the series of races leading up to the Daytona 500.
The Oeiras International Cross Country is an annual cross country running competition that takes place in Oeiras, Portugal. Established in 2000, it is usually held in mid-November and is traditionally the first competition of the IAAF's cross country season, which culminates each year in the IAAF World Cross Country Championships.

The Pacific motorcycle Grand Prix was a round of the FIM Grand Prix motorcycle racing championship between 2000 and 2003.

The U.S. Virgin Islands Paradise Jam is a college basketball tournament that takes place in late November of each year, with the men usually playing the week before Thanksgiving and the women playing Thanksgiving week. It normally takes place in St. Thomas at the Sports and Fitness Center on the campus of the University of the Virgin Islands.

The Rock 'n' Roll Nashville Marathon, previously known as the Country Music Marathon (2000–2015), is an annual marathon, half marathon, and 5K run that has been held in Nashville, Tennessee, since 2000. The marathon is followed by an evening country music concert.

The Samsung Securities Cup was a professional tennis tournament played on outdoor hard courts. It was part of the Association of Tennis Professionals (ATP) Challenger Tour and the ITF Women's Circuit. The men's event was held annually in Seoul, South Korea, from 2000 to 2013, the women's event parallel from 2011 to 2013.

The Peugeot Slovak Open is a professional tennis tournament played on indoor hard courts. It is currently part of the Tretorn SERIE+ of Association of Tennis Professionals (ATP) Challenger Tour and ITF Women's Circuit. It is held at the Národné Tenisové Centrum in Bratislava, Slovakia, since 2000.

The Southern Derby is a fan-based U.S. professional soccer cup competition between USL Championship (USLC) teams based in the South-Atlantic region of the United States. It was founded in 2000.

Streetball Kosova is a traditional streetball tournament held since 2000, organised in the amphitheatre of the swimming pool in Germia Park, Pristina, Kosovo. Streetball Kosova 2014 was the 15th edition in a row without any break.

The Tallahassee Tennis Challenger is a professional tennis tournament played on green clay courts. It is currently part of the Association of Tennis Professionals (ATP) Challenger Tour. It is held annually at the Forestmeadows Tennis Complex in Tallahassee, Florida, United States, since 2000.

The Tallinn Marathon is an annual road marathon, held in Tallinn, Estonia. It is held in September and is the biggest annual marathon in Estonia. Both the marathon and the half marathon held the day before are categorized as Bronze Label Road Races by World Athletics.

The Torneo Internazionale Regione Piemonte was a women's professional tennis tournament played on outdoor clay courts. The event was classified as an ITF $100,000 Tournament. It was held annually in Biella, Italy, from 2000 to 2012.

The Toronto Waterfront Marathon is an annual marathon held in Toronto, Ontario, Canada in October. The race day also includes a half marathon and 5 km race.

The Udine Half Marathon is an annual road running event over the half marathon distance (21.1 km/13.1 mi) which takes place in late September in Udine, Italy.

The Valspar Championship is a professional golf tournament on the PGA Tour, played annually on the Copperhead Course at Innisbrook Resort and Golf Club in Palm Harbor, northwest of Tampa, Florida.

The Wales Open is a professional golf tournament on the European Tour. It was founded in 2000 and played annually through 2014, when a 15-year deal between the tour and the Celtic Manor Resort, that included staging the 2010 Ryder Cup, came to an end. The tournament returned in 2020 as part of a revamp of the European Tour's schedule in response to the impact of the COVID-19 pandemic. The event was part of a 6-week "UK Swing" and was again be hosted at Celtic Manor.

The Women's FA Community Shield is an association football match in England. It is a national super cup, and the equivalent of the FA Community Shield in male football. It is the first competitive match of the football season. The match is competed between the champions of the FA Women's Super League and the winners of the Women's FA Cup. If the Super League champions also win the FA Cup, the Cup runners-up play the match.

The Australia Women's National Wheelchair Basketball League (WNWBL) is a women's semi-professional wheelchair basketball league in Australia.

The World Cyber Games (WCG) is an international esports competition with multi-game titles in which hundreds of esports athletes from around the world participate in a variety of competitions also known as Esports Olympics. WCG events attempt to emulate a traditional sporting tournament, such as the Olympic Games; events included an official opening ceremony, and players from various countries competing for gold, silver, and bronze medals. WCG are held every year in other cities around the world. The WCG 2020 competition received nearly 650 million views worldwide.