
Omar Federico Alderete Fernández is a Paraguayan professional footballer who plays as a centre-back for Bundesliga club Hertha BSC and the Paraguay national team.

Miguel Ángel Almirón Rejala is a Paraguayan professional footballer who plays as an attacking midfielder for Premier League club Newcastle United and the Paraguay national team.

Júnior Osmar Ignacio Alonso Mujica is a Paraguayan footballer who plays either as a centre back or a left back for Brazilian club Atlético Mineiro and the Paraguay national team.

Eduardo Aranda is a Paraguayan footballer who plays for Cusco FC.

Víctor Hugo Ávalos Acosta was a Paraguayan footballer, most remembered for his spells at Quilmes, Independiente Medellín and Chilean football.

Édgar Osvaldo Barreto Cáceres is a Paraguayan professional footballer who plays as a midfielder for Dutch club NEC Nijmegen.

Delfín Benítez Cáceres was a Paraguayan football striker.

César Iván Benítez is a Paraguayan football defender who currently plays for 12 de Octubre.

Ángel Antonio Berni Gómez was a football striker.

Luis Nery Caballero Chamorro is a Paraguayan footballer who plays as a forward for Sportivo Luqueño of the Paraguayan Primera División. His father Luis was a member of the Paraguay national football team at the 1986 FIFA World Cup in Mexico.

Mauro Andrés Caballero Aguilera is a Paraguayan football striker who plays for Arouca. He is the son of Mauro Caballero Senior who played for the club Libertad.

Salvador Cabañas Ortega is a Paraguayan former professional footballer who played as a striker.

Raúl Alejandro Cáceres Bogado is a Paraguayan footballer who plays for Cruzeiro.

Víctor Javier Cáceres Centurión is a Paraguayan footballer. He currently plays as defensive midfielder for Club Nacional and also for Paraguay national team.

Verónica Cepede Royg is a professional Paraguayan tennis player.

Paulo César da Silva Barrios is a Paraguayan footballer who plays for 12 de Octubre in Paraguay, as a centre back.

Rossana Neffa de los Rios is a retired tennis player from Paraguay.

Ramón Delgado is a retired tennis player and current tennis coach from Paraguay. He turned professional in 1995 and achieved a career-high singles ranking of World No. 52 in April 1999. He reached the ATP final at Bogotá in 1998 and the fourth round of the 1998 French Open, defeating Pete Sampras in the second round.

Cecilio Andrés Domínguez Ruiz is a Paraguayan professional footballer who plays as a left-winger and forward for Austin FC of Major League Soccer and the Paraguay national team.

Julio Daniel dos Santos Rodríguez is a Paraguayan footballer who plays for Cerro Porteño.

Arsenio Pastor Erico Martínez was a Paraguayan football striker. He is the all-time highest goalscorer in the Argentine first division, with 295 goals according to Argentine Football Association. Previously it had been affirmed that Erico's record was 293 goals, sharing the record with Angel Labruna All the goals in Erico's career in Primera División were scored playing for Independiente. Erico is also considered the best Paraguayan footballer of all time and for some is the best player in history, including Alfredo Di Stefano. A striker noted for his technique, finishing and aerial ability, Erico was one of the finest players of the 1930s and one of greatest players to have played in the Argentinean league.

Pablo Daniel Escobar Olivetti is a Paraguayan-born Bolivian former footballer who last played for Bolivian Primera División club The Strongest as an attacking midfielder or second striker.

Roberto Júnior "Gatito" Fernández Torres is a Paraguayan footballer who plays as a goalkeeper for Brazilian club Botafogo.
Manuel Fleitas Solich was a Paraguayan football player and coach. He was known as "El Brujo".
Ángel Franco is a Paraguayan professional golfer. His brother is golfer Carlos Franco.

Leryn Dahiana Franco Steneri is a Paraguayan model, actress and former athlete who currently works for the athletics department of Club Sol de América. Franco participated at the 2004, 2008 and 2012 Olympics competing in the javelin throw.

Liz Camila Giangreco Campiz is a Paraguayan tennis player.

Juan Carlos "Toro" Giménez Ferreyra is a Paraguayan boxer. During his career he was WBC International light heavyweight champion and unsuccessfully fought for the World Super Middleweight title four times, first against Mauro Galvano in 1992, then against Chris Eubank the same year, against Nigel Benn in 1994 and finally against Joe Calzaghe in 1998, losing via knockout.

Montserrat González Benítez is a Paraguayan tennis player.

Julieta Granada is a Paraguayan professional golfer on the U.S.-based LPGA Tour and the Ladies European Tour.

Miguel Isaías Jacquet Duarte is a Paraguayan professional footballer who plays as a centre-back for Club Nacional de Football.

Ángel Críspulo Jara Saguier is a Paraguayan former footballer. Angel is one of the seven Jara Saguier brothers that played professional football in Paraguay.

Darío Lezcano Mendoza is a Paraguayan professional footballer who plays for Liga MX club Juárez and the Paraguay national team. He represented Paraguay at Under-17 level from 2006 to 2007 and later at full international level from 2015 to 2017, scoring 4 goals during the 2018 FIFA World Cup qualifiers.

Rubén Dario Maldonado Brizuela is a former Paraguayan football defender who last played for Nacional in the Paraguayan Primera División.

Diego Mendieta was a Paraguayan footballer who played as a forward for Persis Solo F.C.. His death on 3 December 2012 reportedly caused by cytomegalovirus, an easily treatable disease, sparked international outrage after it was made known that his club refused to pay his hospital fees, thus resulting in his demise. The club also owed Mendieta an estimated US$12,500 in salaries which had prevented him from returning to his native Paraguay. The International Federation of Professional Footballers (FIFPro), a worldwide representative organisation for professional football players, dubbed his death as a "disgrace for football".

Derlis David Meza Colli, simply known as David Meza, is a Paraguayan football midfielder who plays for Argeș Pitești in the Romanian Liga I.

Claudio Marcelo Morel Rodríguez is a Paraguayan former footballer who last played for Sarmiento de Leones in the Torneo Federal B.

Celso Fabián Ortiz Gamarra, commonly known as Celso Ortiz, is a Paraguayan professional footballer, currently playing as a midfielder for Liga MX club Monterrey and the Paraguay national team.

Danilo Fabián Ortiz Soto is a Paraguayan footballer who plays as a centre back for Argentine club Godoy Cruz.
Paolo Roberto Ortíz is a Paraguayan football goalkeeper who currently plays for General Caballero.

Richard Ortiz Busto, is a Paraguayan footballer who plays as defensive midfielder. He currently plays for Primera División Paraguaya club Olimpia Asunción in Paraguay, and the Paraguay national football team. Ortiz is a fast player who plays as a central/defensive midfielder and is renowned for his long-distances strikes with his left foot. He ranked number 5 in a list of the most expensive players in Paraguayan football for 2015 published by Diario Extra.

Víctor Pecci Sr. is a former professional tennis player from Paraguay.

Robert Ayrton Piris Da Motta Mendoza is a Paraguayan professional footballer who plays as a defensive midfielder for Turkish club Gençlerbirliği on loan from Flamengo, and the Paraguay national team.

Iván Rodrigo Piris Leguizamón is a Paraguayan footballer who plays as a full-back for Club Libertad.

Marcos Antonio Riveros Krayacich is a Paraguayan footballer who plays for Cerro Porteño and the Paraguay national team as a central midfielder.

Roque Luis Santa Cruz Cantero is a Paraguayan footballer who plays as a striker for, and captains both Paraguayan club Club Olimpia and Paraguay national team. He is the record goal scorer and has earned over 100 caps for the Paraguay national team, thus he is regarded as one of the best players in the nation's history.

Pedro Alcides Sarabia Achucarro is a Paraguayan football manager and former player who played as a defender. He is the current manager of 12 de Octubre.

Werner Luis Schuler Gamarra is a Peruvian footballer who plays as a centre back. Schuler currently plays for Universidad San Martín in the Torneo Descentralizado on loan from Universitario.

Antony Domingo Silva Cano, commonly known as Antony Silva or mistakenly as Anthony Silva, is a Paraguayan footballer who plays as goalkeeper for Liga MX club Puebla and the Paraguay national team. Silva also holds Italian citizenship.

Constantino Urbieta Sosa was a Paraguayan-Argentine footballer that played as a midfielder.
Fabrizio Zanotti is a Paraguayan professional golfer who plays on the European Tour.