
The 1915 Clemson Tigers football team represented the Clemson Tigers of Clemson Agricultural College during the 1915 college football season. Under third year head coach Bob Williams, the team posted a 2–4–2 record in the Southern Intercollegiate Athletic Association. W. K. McGill was the captain. The 1915 season saw the introduction of Riggs Field as Clemson's home stadium. Riggs would host the football team until Memorial Stadium was built in 1942.

The 1915 Illinois Fighting Illini football team was an American football team that represented the University of Illinois during the 1915 college football season. In their third season under head coach Robert Zuppke, the Illini compiled a 5–0–2 record and finished as co-champions of the Western Conference. Center John W. Watson was the team captain.
The 1915 LSU Tigers football team represented the LSU Tigers of Louisiana State University during the 1915 Southern Intercollegiate Athletic Association football season.

The 1915 Montana football team represented the University of Montana in the 1915 college football season. They were led by first-year head coach Jerry Nissen, played their home games at Dornblaser Field, and finished the season with a record of 2–2–2.

The 1915 Navy Midshipmen football team represented the United States Naval Academy during the 1915 college football season. In its first season under head coach Jonas Ingram, the team compiled a 3–5–1 record and was outscored by a combined score of 118 to 99.

The 1915 Notre Dame Fighting Irish football team represented the University of Notre Dame during the 1915 college football season.

The 1915 Penn State Nittany Lions football team represented the Pennsylvania State University in the 1915 college football season. The team was coached by Dick Harlow and played its home games in New Beaver Field in State College, Pennsylvania.

The 1915 Rutgers Queensmen football team represented Rutgers University in the 1915 college football season. In their third season under head coach George "Sandy" Sanford, the Queensmen compiled a 7–1 record and outscored their opponents, 351 to 33. The team shut out four of its eight opponents, and its only loss was to Princeton by a 10 to 0 score. Coach Sanford was inducted into the College Football Hall of Fame in 1971.

The 1915 Washington football team was an American football team that represented the University of Washington during the 1915 college football season. In its eighth season under coach Gil Dobie, the team compiled a 7–0 record, shut out five of seven opponents, and outscored all opponents by a combined total of 274 to 14. Ray Hunt was the team captain.