Calappilia is an extinct genus of box crabs belonging to the family Calappidae. The type species of the genus is Calappilia verrucosa.

This is a list of gomphothere fossils found in South America. Gomphotheres were elephant-like mammals that lived from the Middle Miocene to the Holocene.

Gryposuchus is an extinct genus of gavialoid crocodilian. It is the type genus of the subfamily Gryposuchinae. Fossils have been found from Argentina, Colombia, Venezuela, Brazil and the Peruvian Amazon. The genus existed during the Miocene epoch. One recently described species, G. croizati, grew to an estimated length of 10 metres (33 ft).
Hapalops is an extinct genus of ground sloth from the Early to Late Miocene of Brazil, Bolivia, Colombia, and Argentina in South America.

The Iguape Formation is a geological formation of the Santos Basin offshore of the Brazilian states of Rio de Janeiro, São Paulo, Paraná and Santa Catarina. The calcarenite, shale, siltstone, marl and conglomerate formation dates to the Tertiary period and has a maximum thickness of 2,200 metres (7,200 ft).

The Marambaia Formation is a geological formation of the Santos Basin offshore of the Brazilian states of Rio de Janeiro, São Paulo, Paraná and Santa Catarina. The predominantly shale and marl formation dates to the Tertiary period and has a maximum thickness of 2,700 metres (8,900 ft). The formation is a seal and reservoir rock of the Atlanta and Oliva Fields in the Santos Basin.

Metaxytherium is an extinct genus of dugong that lived from the Miocene until the end of the Pliocene. Fossil remains have been found in Africa, Asia, Europe, North America, and South America.

Paraphysornis is an extinct genus of giant flightless terror birds that inhabited Brazil during Late Oligocene or Early Miocene epochs.
Purussaurus is an extinct genus of giant caiman that lived in South America during the Miocene epoch, from the Colhuehuapian to the Montehermosan in the SALMA classification. It is known from skull material found in the Brazilian and Peruvian Amazon, Colombian Villavieja Formation, Panamanian Culebra Formation and the Urumaco and Socorro Formations of northern Venezuela.

Stupendemys is a prehistoric genus of freshwater side-necked turtle. Its fossils have been found in northern South America, in rocks dating from the Middle Miocene to the very start of the Pliocene, about 13 to 5 million years ago.

Trigodon is an extinct genus of the family Toxodontidae, a large bodied notoungulate which inhabited South America during the Late Miocene to Early Pliocene, living from 11.61—4.0 Ma and existed for approximately 7.61 million years . The type species is T. gaudryi.

Xenastrapotherium is an extinct genus of astrapothere, a type of hoofed herbivorous mammal, native to South America, which lived in the Middle to Late Miocene period, typically during the Laventan stage. It is a member of the family Astrapotheriidae in the subfamily Uruguaytheriinae, large astrapotheres, equipped with a trunk-like nose and protruding teeth, similar to the elephants, but their tusks were the canine teeth, not the incisors. Xenastrapotherium was a genus widely distributed in northern South America, in contrast to other species of astrapotheres which lived in the area of the Southern Cone of the continent. It differed from other astrapotheres by having two lower incisors on each side of the jaw and the tusks have a pronounced longitudinal curvature, although their general shape and size are probably very similar to Astrapotherium, whose weight would be 900 to 1,500 kilograms, comparable to the current black rhino.