
The Alai-Western Tian Shan steppe ecoregion covers the foothills on the western edge of the Tien Shan and Alay Mountains of Central Asia. This territory is mostly in southeastern Uzbekistan, with a portion running north into Kazakhstan on the east side of the Syr Darya River, and a small portion in Turkmenistan.

The Badghyz and Karabil semi-desert ecoregion covers the hills north of the central mountain ranges of Afghanistan, southeast Turkmenistan, and portions of Uzbekistan and Tajikistan. The landscape has been described as "savannah-like" and reminiscent of Africa, with desert sedges (Carex) and stands of wild pistachio trees. The area supports high biodiversity and a number of rare and endemic species, such as the endangered Turkmenian kulan (Equus hemionus kulan).

The Caspian lowland desert ecoregion is an ecoregion that covers the north and southeast coasts of the Caspian Sea, including the deltas of the Volga River and Ural River in the northern region. While the region gets relatively low amounts of precipitation, wildlife is supported by the river estuaries and the sea itself. The wetlands are an internationally important area for bird nesting and migratory resting. The ecoregion is in the Palearctic realm, and the deserts and xeric shrublands biome. It has an area of 267,300 square kilometres (103,200 sq mi).

The Central Asian riparian woodlands ecoregion is spread out across the deserts and plains of central Asia between the Aral Sea and the mountains 2,000 kilometres (1,200 mi) to the east. The long narrow components of the ecoregion follow the large rivers fed by snowmelt, and provide a critical habitat for migratory birds as they travel through the arid region. The vegetation is referred to as tugai, characterized by low tangles of trees and brush along the edges of the rivers and associated wetlands, and fed by groundwater instead of precipitation.

The Central Asian southern desert ecoregion is an arid but ecologically active region between the east coast of the Caspian Sea and steppes at the base of the mountains of central Asia. Most of Turkmenistan and eastern Uzbekistan is in this ecoregion. The winters are milder than in the cold desert to the north, and a large number of endemic species have adapted to living in the particular climate and soil of the region. As with sandy deserts in general, the region is notable for high numbers of endemic species of reptiles and insects.

The Kopet Dag semi-desert ecoregion is a small ecoregion that crosses the border of southwestern Turkmenistan into northeastern Iraq. It covers a transition zone between the deserts to the north and west, and the foothill steppes and woodlands in the higher Kopet Dag mountains to the east and the Alborz Mountains to the south. The terrain is mostly barren semi-desert and widespread 'takir', a type of seasonal salt flat or dried clay deposit in an interdune depression.

The Kopet Dag woodlands and forest steppe ecoregion coincides with the Kopet Dag mountains, straddling the southern border of Turkmenistan and the northeastern border of Iran. The region is one of high biodiversity, as it includes a full range of altitude zones, and variety of habitats included juniper-wooded slopes, montane grasslands, and tugay.