The history of Madeira begins with the discovery of the islands by Portugal in 1419. There is no record of anyone living on the islands at that time. Portugal began colonizing the island in 1420.

Missas do Parto are one of the greatest Christmas traditions of the Autonomous Region of Madeira in Portugal. They consist of nine masses celebrated in the novena before Christmas Day - from 16 to 24 December - in all the parishes of the Autonomous Region, at the end of the morning. They are a Marian devotion and celebrate the pregnancy of the Virgin Mary, in the figure of Our Lady of Ó who, in Madeira, is called Our Lady of Birth. After the Masses of the Childbirth there follows the Mass of the Rooster, on the night of 24 December.

The Frente de Libertação do Arquipélago da Madeira, or FLAMA, was a right-wing terrorist paramilitary organisation from Madeira, whose main goal was to achieve Madeira's independence from mainland Portugal.

The history of the Jews in Madeira spans the entire length of the history of Madeira itself. The history of Madeira begins with the discovery of the islands by Portugal in 1419. Madeira is presently officially the Autonomous Region of Madeira, and is one of the two autonomous regions of Portugal. It is an archipelago situated in the north Atlantic Ocean, southwest of Portugal. Its total population was estimated in 2016 at 289,000. The capital of Madeira is Funchal, which is located on the main island's south coast.

Paul Langerhans was a German pathologist, physiologist and biologist, credited with the discovery of the cells that secrete insulin, named after him as the islets of Langerhans.

The 2010 Madeira floods and mudslides were the result of an extreme weather event that affected Madeira Island in Portugal's autonomous Madeira archipelago on 20 February 2010. At least 42 people died and at least 100 were injured. However, with at least eight people still missing, the final death toll is still uncertain.

The Monte Railway was a rack railway connecting Pombal, in Funchal, to Terreiro da Luta in Monte, a distance of 3,911 metres, from 1893 to April 1943.

Saudades da Terra is a manuscript that was published by father Gaspar Frutuoso. It forms a reference work on the knowledge of Macaronesia in the late 16th century.

João Gonçalves Zarco was a Portuguese explorer who established settlements and recognition of the Madeira Islands, and was appointed first captain of Funchal by Henry the Navigator.