
Bohemia Interactive a.s. is a Czech video game developer and publisher based in Prague. The company focuses on creating military simulation games such as Operation Flashpoint: Cold War Crisis and the ARMA series. It is also known for having worked on a game conversion of the DayZ mod created for ARMA 2.

CBE Software is an indie video game developer based in the Czech Republic. It was founded in 2006 as Cardboard Box Entertainment (CBE). The first released title was an adventure game Ghost in the Sheet. The studio was then inactive for a few years and its members worked on titles such as Dark Fall II: Lights Out, Barrow Hill and Tale of a Hero.

Cinemax is an independent Czech video game developer and publisher. The studio was founded by Lukáš Macura. The studio focuses on computer, mobile and console games.

Dreadlocks Ltd is a Czech video game developer based in Prague. The company's first game, Rune Legend, was the winner of 5th AppParade. The company was officially formed in 2011. The company's most recent release is Dex, an action role-playing game.

Geewa is a Czech mobile games developer based in Prague. Founded in 2005, the company develops and publishes casual competitive multiplayer games for mobile devices. Geewa was awarded the Red Herring 100 Europe award in 2013 and is best known for their games Smashing Four and Pool Live Tour. In 2017 Geewa lost CZK 18 mio. on sales CZK 26 mio., cumulated loss increased to CZK 174 mio.

Grip Digital is a developer and publisher of video games based in Prague, Czech Republic. It focuses on developing an publishing video games. Its main focus are consoles.

Hexage is a Czech video game developer, based in Mníšek pod Brdy but registered in the United Kingdom. The company has produced multiple titles for mobile devices. A few of studio's games have surpassed a million downloads. The most successful title is Reaper: Tale of a Pale Swordsman.

Keen Software House is an independent video game developing company based in Prague, Czech Republic. The company was founded by Marek Rosa in 2010.

Rake In Grass is an independent video game developer based in the Czech Republic. The studio makes computer, mobile and console games. The studio was nominated for an award in artistic contribution to Czech video game output in 2012.

SCS Software s.r.o. is a Czech video game development company based in Prague, Czech Republic. It primarily produces simulation games for Microsoft Windows, OS X, and Linux, including the 18 Wheels of Steel and Truck Simulator series.

Trickster Arts is an indie game development team based in the Czech Republic. It consists of former 2K Czech employees.