
The Fontignano Madonna is a 1522 fresco Madonna and Child by Perugino. Angniolus Toni Angeli and the Confraternity of the Annunciation commissioned him to decorate their church of S. Maria dell'Annunziata in Fontignano in 1521. It is his only surviving work in the church and probably reused his cartoons from Santa Maria Maggiore in Spello, such as those for the Spello Pietà. Angeli's name appears at the base of the work.

Madonna and Child is an oil on oak panel painting by Perugino. It dates to around 1501 and is now in the National Gallery of Art in Washington.

Madonna and Child with St Herculanus and St Constantius or Madonna of the Kitchen is a 1515 painting by Perugino, now in the Galleria Nazionale dell'Umbria in Perugia. Its title refers to the fact that it once hung in the former kitchen of the Palazzo dei Priori in Perugia. The two accompanying saints are Herculanus and Constantius, both local saints to Perugia.

Madonna and Child with St John the Baptist and St Augustine is a c.1494 painting by Perugino of the Madonna and Child enthroned between John the Apostle and Augustine of Hippo. It is in the church of Sant'Agostino in Cremona. It was commissioned in 1493 by the rich Roncadelli family and the follow year he painted it at his Florence studio before shipping it to Cremona. It is signed and dated on the throne Petrus Perusinus pinxit MCCCCLXXXXIIII.

Madonna and Child with St John the Baptist and St Catherine of Alexandria is a c.1495 oil on panel painting by Perugino of the Madonna and Child with John the Baptist and Catherine of Alexandria. It is now in the Louvre in Paris.
Madonna and Child with St Rose and St Catherine is a c.1490–1492 tondo oil on panel painting by Pietro Perugino and Andrea Aloigi. It shows the Madonna and Child with Rose of Viterbo and Catherine of Alexandria surrounded by angels It was sold from the collection of William II of the Netherlands in 1850 to the Louvre, where it now hangs.

Madonna and Child with the Infant John the Baptist is an oil on oak panel painting by Perugino, dating to around 1497 and now in the Städel Museum in Frankfurt-am-Main

Madonna and Child with Two Saints is a tempera on panel painting by Perugino, dating to around 1495. It is now in the Kunsthistorisches Museum in Vienna. The saint to the right is Catherine of Alexandria, whilst the saint to the left is unidentified but may be Rose of Viterbo or Mary Magdalene.

Madonna del Sacco is an oil on panel painting by Perugino, dating to around 1495-1500. It shows the Madonna and Child with the infant John the Baptist and an angel. It is now in the Galleria Palatina in Florence.

Madonna della Consolazione is a c.1496-1498 oil on panel painting by Perugino, now in the Galleria Nazionale dell'Umbria in Perugia. Produced at the same time as the artist's work on the Sala delle Udienze del Collegio del Cambio, it was completed in April 1498.

The Madonna in Glory with Saints is a painting by the Italian Renaissance painter Pietro Perugino, dating to c. 1500–1501. It is housed in the Pinacoteca Nazionale of Bologna, Italy.

The Madonna of Loreto is a c.1507 oil on panel painting by Perugino, now in the National Gallery, London, which bought it in 1879. It shows the Madonna and Child flanked by Jerome (left) and Francis of Assisi (right). Two angels hover over Mary's head holding a crown. It reuses the low parapet from Madonna and Child with St Rose and St Catherine (1492) and probably also involved the master's studio assistants.