
Banshee is a cross-platform open-source media player, called Sonance until 2005. Built upon Mono and Gtk#, it uses the GStreamer multimedia platform for encoding and decoding various media formats, including Ogg Vorbis, MP3 and FLAC. Banshee can play and import audio CDs and supports many portable media players, including Apple's iPod, Android devices and Creative's ZEN players. Other features include Last.fm integration, album artwork fetching, smart playlists and podcast support. Banshee is released under the terms of the MIT License. Stable versions are available for many Linux distributions, as well as a beta preview for OS X and an alpha preview for Windows.

Exaile is a cross-platform free and open-source audio player, tag editor and library organizer. It was originally conceived to be similar in style and functions to KDE's Amarok 1.4, but uses the GTK+ widget toolkit rather than Qt. It is written in Python and utilizes the GStreamer media framework.

gtkpod provides a graphical user interface that enables users of Linux and other Unix operating systems to transfer audio files onto their iPod Classic, iPod Nano, iPod Shuffle, iPod Photo, or iPod Mini music players. Although it does not support some of the more advanced features of iTunes, gtkpod still performs the role of an iPod manager for Linux. Album art and videos are now supported, and preliminary support for jailbroken iPhones and iPod Touches is available.

iPodLinux is a µClinux-based Linux distribution designed specifically to run on Apple Inc.'s iPod. When the iPodLinux kernel is booted it takes the place of Apple's iPod operating system and automatically loads Podzilla, an alternative GUI and launcher for a number of additional included programs such as a video player, an image viewer, a command line shell, games, emulators for video game consoles, programming demos, and other experimental or occasionally unfinished software.

iRip is a commercial iPod recovery tool for Mac OS X, Windows XP and Windows Vista. It features an iTunes style interface, iPod media transfer, and integration with iTunes. It was originally released in August 2003 and has since had over 5 million downloads.

iSync is a software application first released by Apple Inc. on Jan 2, 2003. Apple licensed the core technology from fusionOne. It ran only under Mac OS X and was used to synchronize contact and calendar data from Address Book and iCal with many non-Apple SyncML-enabled mobile phones via a Bluetooth or USB connection. Support for many devices was built-in, with newer devices being supported via manufacturer and third-party iSync Plugins. Support for Palm OS organizers and compatible smartphones was removed with the release of iSync 3.1 and Mac OS X 10.6 Snow Leopard. BlackBerry OS, Palm OS, and Windows Mobile devices could not be used with iSync, but were supported by third-party applications. Before the release of Mac OS X 10.4, iSync also synchronized a user's Safari bookmarks with the then .Mac subscription service provided by Apple.

iTunes is a media player, media library, Internet radio broadcaster, mobile device management utility, and the client app for iTunes Store, developed by Apple Inc. It is used to purchase, play, download, and organize digital multimedia, on personal computers running the macOS and Windows operating systems, and can be used to rip songs from CDs, as well as play content with the use of dynamic, smart playlists. Options for sound optimizations exist, as well as ways to wirelessly share the iTunes library.

MediaMonkey for Windows is a digital media player and media library application developed by Ventis Media Inc., for organizing and playing audio on Microsoft Windows operating systems. By using plugins, it can be extended to handle video and other media formats as well. MediaMonkey is commonly displayed/marketed as a solution for managing large libraries of music.

MusicBee is a freeware media player for playback and organization of audio files on Microsoft Windows, built using the BASS audio library.

News360 is a personalized news aggregation app for smartphones, tablets and the web. It attempts to learn a user's interests by analyzing their interaction with news stories on the app and using semantic analysis and natural language processing to create an Interest Graph and construct a unique feed of relevant content for each user. The app has an audience of more than 4M users and is located in San Francisco, CA, with offices in Vancouver, BC and Moscow, Russia.

Nightingale is a discontinued free, open source audio player and web browser based on the Songbird media player source code. As such, Nightingale's engine is based on the Mozilla XULRunner with libraries such as the GStreamer media framework and libtag providing media tagging and playback support, amongst others. Since official support for Linux was dropped by Songbird in April 2010, Linux-using members of the Songbird community diverged and created the project. By contrast to Songbird, which is primarily licensed under the GPLv2 but includes artwork that is not freely distributable, Nightingale is free software, licensed under the GPLv2, with portions under the MPL and BSD licenses.

Rockbox is a free and open-source software replacement for the OEM firmware in various forms of digital audio players (DAPs) with an original kernel. It offers an alternative to the player's operating system, in many cases without removing the original firmware, which provides a plug-in architecture for adding various enhancements and functions. Enhancements include personal digital assistant (PDA) functions, applications, utilities, and games. Rockbox can also retrofit video playback functions on players first released in mid-2000. Rockbox includes a voice-driven user-interface suitable for operation by visually impaired users.

Senuti is a Mac OS X computer application written by Whitney Young. It was released on April 19, 2006, for copying songs from an iPod to a Macintosh computer running Mac OS X 10.5 or later. According to FadingRed, the company that sells and distributes Senuti, it has been downloaded over 2 million times.

Songbird is a discontinued music player originally released in early 2006 with the stated mission "to incubate Songbird, the first Web player, to catalyze and champion a diverse, open Media Web".

Style Jukebox was a hi-fi high-resolution audio cloud music streaming and storage player for the Windows, iOS, Android and Windows Phone platforms. A Web Player was also available for Mac, Windows and Linux.

Trove was a social news aggregation web and mobile application, with apps available on iOS, Android, and Fire Phone. Trove is also the name of the company behind the application.

Typeeto is a software tool that enables using a Macintosh Bluetooth compatible keyboard with iOS and Android devices, Apple TV and game consoles.

Winamp is a media player for Microsoft Windows originally developed by Justin Frankel and Dmitry Boldyrev by their company Nullsoft, which they later sold to AOL in 1999 for $80 million. It was then acquired by Radionomy in 2014. Since version 2 it has been sold as freemium and supports extensibility with plug-ins and skins, and features music visualization, playlist and a media library, supported by a large online community.