
Strange and exotic weapons are a recurring feature in science fiction. In some cases, weapons first introduced in science fiction have been made a reality; other science-fiction weapons remain purely fictional, and are often beyond the realms of known physical possibility.

The Beetle is the name used by multiple fictional characters appearing in American comic books published by Marvel Comics. It is also the name of three versions of high tech armor used by seven separate characters.

T-900 TOK715 Terminator "Cameron" is a fictional character on the Fox television series Terminator: The Sarah Connor Chronicles which is a spin-off of the Terminator film franchise. Cameron first appeared in the series' pilot episode as an unknown model of Terminator—a fictional type of android envisioned as a soldier and assassin. Cameron is portrayed by actress Summer Glau who, in 2008, won a Saturn Award for Best Supporting Actress on Television for her performance.

The Deathclaw is a fictional reptilian species from the post-apocalyptic Fallout video game franchise. They were created by humans as biological weapons prior to the series' in-universe nuclear war. Escaping into the wild afterwards, they went on to thrive in the nuclear wasteland, becoming apex predators. Known as one of the Fallout series' most recognizable and iconic elements, Deathclaws were praised by critics for their design and the fear they induce in the player due to their immense power. As a result of their popularity, numerous mods were created for Fallout series games with the Deathclaw as a central theme, either to tame the creatures as a pet or use them in combat, concepts which were later added as an official feature.

Doomsday is a fictional supervillain appearing in American comic books published by DC Comics, commonly as one of the deadliest foes of Superman, as well as the Justice League. Created by writer-artist Dan Jurgens, the character had a cameo appearance in Superman: The Man of Steel #17 and made his first full appearance in Superman: The Man of Steel #18.

A doomsday device is a hypothetical construction — usually a weapon or weapons system — which could destroy all life on a planet, particularly Earth, or destroy the planet itself, bringing "doomsday", a term used for the end of planet Earth. Most hypothetical constructions rely on hydrogen bombs being made arbitrarily large, assuming there are no concerns about delivering them to a target or that they can be "salted" with materials designed to create long-lasting and hazardous fallout.

Eradicator is the given name of four different fictional comic book characters, appearing in books published by DC Comics. The first iteration was an antihero character appearing in The Flash series of comics. The second was a superhero having a recurring role in Superman stories, and the remaining two first appeared in 2013 and 2017, respectively.

The Gnasher Shotgun, also known as simply the Gnasher, is a fictional firearm weapon featured in the Gears of War video game franchise. First appearing in the original Gears of War, the Gnasher is the standard-issue shotgun for Coalition of Ordered Governments ("COG") soldiers, although it is also carried by the enemy Locust Horde, particularly the Grenadier class of Locust Drone.

Gort is a fictional humanoid robot that appeared first in the 1951 20th Century Fox American science fiction film The Day the Earth Stood Still and later in its 2008 remake. His depiction varies between film adaptations, however, the original character was loosely based on the character Gnut, from "Farewell to the Master", a 1940 Astounding Science Fiction short story written by Harry Bates, used as the basis for Andrew Phillips's screenplay. In that story, Gnut is a moving green statue that is apparently attendant upon Klaatu, but in the terminus of the story is identified as the eponymous "master" over Klaatu.

Iron Man's armor is a fictional powered exoskeleton appearing in American comic books published by Marvel Comics and is worn by comic book superhero Tony Stark when he assumes the identity of Iron Man. The first armor, was designed by artists Don Heck and Jack Kirby, and first appeared, along with Tony Stark, in Tales of Suspense #39.

KOS-MOS is a fictional character from the Xenosaga role-playing video game series by Monolith Soft and Bandai Namco Entertainment. KOS-MOS also appears as a major character in the anime Xenosaga: The Animation and in several crossover video games.

The Lancer Assault Rifle, also known as simply the Lancer, is a fictional class of firearm weapons featured in the Gears of War media franchise. Variants of the Lancer appear in the video game series as well as in related media, beginning with Gears of War. The most well known model is the Mark (MK) 2 Lancer Assault Rifle, a mid-range assault rifle with a fully operational chainsaw for a bayonet, and is usually available as one of the starting weapons used by the protagonists of the series.

The M6D Pistol, also known as the Halo CE pistol, M6D Magnum Sidearm or M6D Personal Defense Weapon System, is a fictional pistol featured in the Halo franchise of video games. It is one of the starting weapons used by the protagonist, Master Chief, and was designed and manufactured by Misriah Armory, a manufacturer for the United Nations Space Command. Called one of the most infamous video game weapons of all time, it has gained notoriety amongst critics and players for its unusually high power and accuracy, especially for the time it is received in the game. The pistol, or variants of it, appeared in several games in the series, starting in Halo: Combat Evolved, as well as in related media.

The term mecha may refer to both scientific ideas and science-fiction genres that center on giant robots or machines (mechs) controlled by people. Mechas are typically depicted as humanoid mobile robots. The term was first used in Japanese (meka) after shortening the English loanword mekanizumu or mekanikaru , but the meaning in Japanese is more inclusive, and "robot" (robotto) or "giant robot" is the narrower term.

Megatron is a fictional character from the Transformers franchise created by American toy company Hasbro in 1984, based on a design by Japanese toy company Takara. Usually portrayed as a villain, Megatron is the supreme leader of the Decepticons, a faction of war mongering Transformers who seek to conquer their home planet of Cybertron and the rest of the known universe. A cruel and power hungry leader, Megatron leads the Decepticons with an iron fist and has little to no tolerance for failure. While some Decepticons under his command have challenged and attempted to take his place as leader, Megatron maintains his power and authority over the Decepticons by proving himself as the most powerful in their ranks. He serves as the nemesis of the Autobot leader Optimus Prime. In most incarnations, after meeting his demise, usually at Optimus' hands, Megatron would be resurrected as Galvatron.

Metal Gear is the name for a series of mecha in the Metal Gear series. In the series, a Metal Gear is defined as a bipedal nuclear weapons-equipped tank. The Metal Gears are typically autonomous nuclear launch platforms which the player must destroy to save the world and complete the game. Often, confronting the latest Metal Gear model is one of the final challenges of each game.

The Nemesis, also called the Nemesis-T Type, the Pursuer or the Chaser , is a fictional character in Capcom's Resident Evil franchise. Although smaller than other Tyrant models, the creature dwarfs a typical human, and possesses vastly superior intelligence and physical dexterity to its undead peers. It features in Resident Evil 3: Nemesis as a titular main villain before later emerging in other titles and cameo roles. It is also featured on various merchandise and was portrayed by Matthew G. Taylor in the 2004 film Resident Evil: Apocalypse. The character is voiced by Tony Rosato in the original game and Gregg Berger in Resident Evil: Operation Raccoon City, In the Resident Evil 3 2020 remake, the character is voiced by David Cockman, while Neil Newbon provided the motion capture performance.
The OMACs are a fictional type of cyborg appearing in comic books published by DC Comics. They are based on the Jack Kirby character of the same name.

The Rev-9 is a fictional android assassin, serving as the main antagonist of Terminator: Dark Fate, the sixth installment in the Terminator series. In its human form, the Rev-9 is portrayed by Gabriel Luna.

A sentient weapon is a common plot device in many works of fantasy, mythology, and science fiction, and is related to the classic motif of the magic sword. Sentient weapons may be human, robotic, or magical, but not all magic weapons are sentient. A sentient weapon may experience a moral conflict from its specific nature as a weapon, or may function as the villain, which, through its intelligence, is able to gain power. Another possibility is that it assists the wielder, or is merely neutral.

The Smart Pistol is a fictional handgun used in the Titanfall series of first-person shooter video games. Created for pilots of the game's mechs, known as Titans, it is used to fight adversaries when the pilot is outside of the mech. The Smart Pistol MK5 appears in the first Titanfall, while the Smart Pistol MK6 appears in Titanfall 2. Known as a "controversial", notorious and divisive weapon due to its ability to automatically target and fire at multiple enemies at once, its power was lowered in the sequel, where it was made a temporary weapon. The Smart Pistol was both criticized for how strong its targeting ability was, and praised for its uniqueness and how it lowered the barrier to entry for players who were new to the genre or normally performed poorly in shooters.

The supersoldier is a fictional concept soldier, often capable of operating beyond normal human limits or abilities either through genetic modification or cybernetic augmentation.
The T-1000 is a fictional character in the Terminator franchise. A shapeshifting android assassin, the T-1000 is the main antagonist of Terminator 2: Judgment Day, as well as a minor antagonist in Terminator Genisys and the theme park attraction T2 3-D: Battle Across Time. A similar Terminator, referred to as a T-1001, appears in the Fox television series, Terminator: The Sarah Connor Chronicles.

The T-3000 is a fictional cyborg assassin, serving as the main antagonist of Terminator Genisys, the fifth installment in the Terminator series, portrayed by Jason Clarke. In the film, the T-3000 is an alternate timeline counterpart of Skynet's nemesis John Connor, created after Skynet infects a variant of Connor with nanotechnology and fractures the timeline. T-3000 also serves as a foil personality to "Guardian", a protagonist who is somewhat similar to T-3000 but also opposite in many ways, of their relationship dynamics with Sarah Connor and Kyle Reese.

The T-X is the name of a fictional cyborg assassin who appears in the Terminator franchise. The T-X model is a gynoid-like assassin with a human-female appearance. The character was introduced as the main antagonist in the 2003 film Terminator 3: Rise of the Machines, portrayed by Kristanna Loken. The T-X has the ability to assume the appearance of other characters; therefore, several other cast members occasionally portrayed the T-X throughout the film. This ability to shapeshift is similar to that of the T-1000, the main antagonist of Terminator 2: Judgment Day.

In the Terminator film series, a Terminator is an autonomous cyborg, typically humanoid, originally conceived as a virtually indestructible soldier, infiltrator, and assassin.

Tyrant is the code name of a series of boss characters in the Resident Evil horror video game series by Capcom, introduced in the original Resident Evil in 1996. Tyrants are towering, biologically engineered supersoldiers created and used by the sinister Umbrella Corporation. Tyrant creatures make appearances as boss characters in most Resident Evil games and the desire to create an obedient bioweapon lies at the core of the series' storyline. Tyrants also appear in other media and merchandise of the Resident Evil franchise, as well as in some unrelated games.

Unicron is a fictional supervillain from the many continuities in the Transformers universe and toyline. Designed by Floro Dery, he was introduced in the 1986 animated film The Transformers: The Movie and has since reappeared in Transformers: Armada, Transformers: Energon, Transformers: Cybertron, Transformers: Prime, Transformers: The Last Knight and Atari's 2004 Transformers video game. Unicron is a prodigiously large robot whose scale reaches planetary proportions, and he is also able to transform into a giant planet. Unicron's origin has expanded over the years from simply being a large robot to being a god of chaos who devours realities. He often employs the help of Decepticons in his work, and in some stories is considered part of the origin of the Decepticon forces.