Enrique Milton Almada Cavo, also known as Quique Almada, was a Uruguayan actor and comedian.

Angel Bonanni is an Israeli actor and model. He is known for his role as Assassin Deacon Mailer in the series Condor, and as Detective Tommy Gibbs in the series Absentia.

Mateo Chiarino is a Uruguayan actor, writer, and director of film, stage, and television. He is currently based in Buenos Aires, Argentina.

Santiago Gómez Cousillas was a classic Uruguayan - Argentine actor who appeared in films between 1936 and 1980.

Daniel Hendler is a Uruguayan film, television, and theatre actor who works mainly in the cinema of Argentina, where he lives. He is known for his starring roles in films such as Bottom of the Sea, Family Law, The Paranoids, Phase 7 and award-winning Lost Embrace by director Daniel Burman, with whom he worked many times. Working on both sides of the Río de la Plata, Hendler achieved international recognition due to his awards as an actor. In 2004, he won the Silver Bear for Best Actor at the Berlin Film Festival for his performance in Lost Embrace. He made his debut as screenwriter and director with the film Norberto's Deadline in 2010. Hendler is part of the generation of actors who revitalized the Uruguayan cinema with films like 25 Watts, and is one of the regular actors of the so-called New Argentine Cinema.

George Hilton, born Jorge Hill Acosta y Lara, was a Uruguayan actor well known for his many spaghetti western performances. Sometimes credited as Jorge Hilton, he appeared in over 20 Euro-westerns as well as several Giallo and action films.

Gustavo Rojo Pinto was a Uruguayan film actor and producer. He appeared in more than 160 films and television shows between 1938 and 2016. He is the father of Ana Patricia Rojo.

Omar Varela is a Uruguayan actor, director, playwright, and teacher, the founder of the theater company Italia Fausta.

Walter Vidarte was a Uruguayan actor.
Martín Pedro Zabalúa Marramoti, known as Tincho Zabala was a Uruguayan film actor.