
Francisco de Paula Aguirre was a Venezuelan composer. He wrote many popular waltzes; his most important works include "Claveles de Galipán", "Que bellas son las flores", "Dama Antañona" and the joropo "Amalia". He died in 1939.

Alejandra Ghersi, better known by the stage name Arca, is a Venezuelan record producer, DJ, singer, and songwriter based in Barcelona. She has released four studio albums—Xen (2014), Mutant (2015), Arca (2017) and Kick I (2020)—and has contributed production work to artists such as Björk, Kanye West, FKA twigs, Kelela, and Frank Ocean.

Diana Arismendi is a Venezuelan composer.
Hugo Blanco was a popular Venezuelan musician. He is best known as the author of "Moliendo Café" and other songs like "El Burrito Sabanero", "Leche Condensada", "Luces de Caracas", "Sierra Nevada" and "Mañanita Zuliana". "Moliendo Café", written in 1958 when Hugo Blanco was only 18 years old, has become one of the most recognized Venezuelan songs in the world.

Tirone José González Orama, known by his stage name Canserbero, was a Venezuelan hip hop singer and songwriter from Caracas. He is regarded as one of the most significant rappers in Latin America. Since he was young, he showed interest in music, mainly influenced by reggaeton but, after the murder of his half brother, his musical references changed to more critical genres such as hip hop and hard rock, appreciable in songs like "Es épico".

María Teresa Gertrudis de Jesús Carreño García was a Venezuelan pianist, soprano, composer, and conductor. Over the course of her 54-year concert career, she became an internationally renowned virtuoso pianist and was often referred to as the "Valkyrie of the Piano". One of her teachers and friends was composer Regina Watson. Carreño was an early adopter of the works of one of her students, American composer and pianist Edward MacDowell (1860–1908) and premiered several of his compositions across the globe. She also frequently performed the works of Norwegian composer and pianist Edvard Grieg (1843–1907). Carreño composed approximately 75 works for solo piano, voice and piano, choir and orchestra, and instrumental ensemble. Several composers dedicated their compositions to Carreño, including Amy Beach and Edward MacDowell.

Reynaldo Hahn was a Venezuelan-born French composer, conductor, music critic, and singer. He is best known for his songs – mélodies – of which he wrote more than 100.

Rházes Hernández López was a Venezuelan composer and flutist born in Caracas June 30, 1918. He died in Caracas in 1991.

Miguel Trost De Pedro, better known by his stage name Kid606, is an electronic musician who was raised in San Diego and later moved to San Francisco. He is most closely associated with the glitch, IDM, hardcore techno, and breakcore scenes.

Alberto Naranjo [nah-rahn'-ho] was a Venezuelan musician. His mother, the singer Graciela Naranjo, was a radio, film and television pioneer in her homeland. Largely self-taught, Naranjo embarked on a similar musical course, becoming – like his mother – one of Venezuela's icons of contemporary popular music.
Jimmy Zambrano, is a Colombian accordion player.