Vartan Adjemian is an Armenian composer of orchestral, operatic and chamber music whose works have been performed worldwide.

Komitas I Aghtsetsi or Komitas I of Aghdznik was a Catholicos of Armenia and Supreme Patriarch as well as the bishop of Taron from 615 until his death in 628. He is known also as Komitas Shinogh, "The Builder" — an allusion to his significant patronage of building and restoration work He was instrumental in the realization of several architectural projects, among which were the complete renovation of the Cathedral at the Holy See of Etchmiadzin; the construction of the Church of St. Hripsime, which stands to this day on the site of an earlier ediface; and the building of the Church of St. Gregory in Dvin.

H.A. Der-Hovagimian, born February 22 in Toronto, Ontario, Canada, is a Canadian-Armenian music composer, songwriter and producer.

Dorians is an Armenian rock band founded in June 2008 by Vahagn Gevorgyan. In February 2009 the band participated at the first qualifying round of the international Eurovision Song Contest, which brought popularity to the band.
Ohan Durian or Duryan was an Armenian conductor and composer.

Andrei Gavrilov is a Swiss pianist of Russian background.

Jivani, born Serob Stepani Levonian, was an Armenian ashugh (bard) and poet.

Tigran Yeghiayi Mansurian is a leading Armenian composer of classical music and film scores, a National Artist of the Armenian SSR (1990) and honored art worker of the Armenian SSR (1984). He is the author of orchestral, chamber, choir and vocal works, which have been played across the world.

Haig Papazian is a Lebanese-Armenian musician who is the lead violinist of alternative rock band Mashrou' Leila.
Karen Sargsyan is an Armenian choirmaster and conductor.

Araksi Sarian-Harutunian was an Armenian musicologist, art history candidate, professor of Yerevan State Conservatory. Honored Art Worker of Armenia (2008). Member of Composers Union of Armenia (1966).

Sayat-Nova was a Georgia-born Armenian poet, musician and ashugh, who had compositions in a number of languages. His songs and poems are in the Armenian, Georgian, Turkish, and Persian languages.

Agapios Tomboulis was a famous Armenian and Greek oud player of rebetiko and Greek folk music, Armenian folk music, Turkish folk music, Jewish folk music born in Constantinople, he is known for being a well known associate of Roza Eskenazi.

Ara Topouzian is an Armenian musician who began playing Armenian and Middle Eastern music in 1991. He plays the kanon.

Avo Uvezian was an Armenian-American cigar manufacturer, jazz pianist and composer.