
Calpernia Sarah Addams is an American author, actress, musician and spokesperson and activist for transgender rights and issues.

Ángela Aguilar Álvarez, known as Ángela Aguilar, is a Mexican-American singer. Born in Los Angeles, while her mother was accompanying her father, Pepe Aguilar, on tour. Aguilar gained notable recognition after performing "La Llorona" at the 19th Annual Latin Grammy Awards in 2018.
Frankie Avalon is an American actor, singer, and former teen idol. Avalon had 31 charting U.S. Billboard singles from 1958 to late 1962, including the number one hits "Venus" and "Why" in 1959.

Desireé Apolonio Bassett is an American rock music guitarist and recording artist. She has performed alongside mainline performers such as Sammy Hagar, Ted Nugent, Living Colour, Barry Goudreau, the Marshall Tucker Band and members of the Allman Brothers Band. She has released two studio albums and has performed on both coasts of the United States.

Emily Jordan Bear is an American composer, pianist, songwriter and singer. After beginning to play the piano and compose music as a small child, Bear made her professional piano debut at the Ravinia Festival at the age of five, the youngest performer ever to play there. She gained wider notice from a series of appearances on The Ellen DeGeneres Show beginning at the age of six. She has since played her own compositions and other works with orchestras and ensembles in North America, Europe and Asia, including appearances at Carnegie Hall, the Hollywood Bowl, the Montreux Jazz Festival and Jazz Open Stuttgart. She has won two Morton Gould Young Composer Awards and was the youngest person ever to win the award. She has also won two Herb Alpert Young Jazz Composers Awards.

David L. Cook is an American Christian country music singer, songwriter and comedian.

Barry Cowsill was an American musician and member of the musical group the Cowsills.

Joshua Coyne is an American musician and composer.

Amala Ratna Zandile Dlamini, known professionally as Doja Cat, is an American singer, rapper and songwriter. Born and raised in Los Angeles, she began making and releasing music on SoundCloud as a teenager. Her song "So High" caught the attention of Kemosabe Records and RCA Records where she signed a joint record deal at the age of 17, subsequently releasing her debut EP Purrr! in 2014.

Eva Quinn Dolan is an American musician and actress, best known for originating the role of Katie in the Broadway adaption of School of Rock.

Eric Gales, also known as Raw Dawg, is an American blues-rock guitarist, originally hailed as a child prodigy. As of 2019 Gales has recorded eighteen albums for major record labels and has done session and tribute work. He has also contributed vocals on several records by the Memphis rap groups Prophet Posse and Three 6 Mafia under the name Lil E.

Gabriella Wilson, better known professionally as H.E.R., is an American singer and songwriter.

Christone "Kingfish" Ingram is an American blues guitarist and singer from Clarksdale, Mississippi, United States, who became a well-known performer as a teenager. His debut album, Kingfish, was released in May 2019. In addition to his own album, musicians he has recorded with include Eric Gales, Buddy Guy and Keb Mo. He has shared the stage with well-known blues artists and younger blues musicians such as the Tedeschi Trucks Band, Samantha Fish, Bob Margolin, Eric Gales, Rick Derringer, Guitar Shorty and Buddy Guy.

Sarah Jarosz is an American singer-songwriter from Wimberley, Texas. Her first album, Song Up in Her Head, was released in 2009 and the tune "Mansinneedof" was nominated for a Grammy Award in the category of Best Country Instrumental Performance. Her second album, Follow Me Down, released in 2011, received a Song of the Year nomination from the Americana Music Association's 2012 Honors and Awards. Her third album, Build Me Up from Bones, was released on September 24, 2013 through Sugar Hill Records. Build Me Up from Bones was nominated for Best Folk Album at the 56th Annual Grammy Awards, and its title track was nominated for Best American Roots Song. In 2016 Jarosz released her fourth album, Undercurrent. The album won two Grammy awards.

Keith Farrelle Cozart, better known by his stage name Chief Keef, is an American rapper, singer, songwriter, and record producer. Cozart's music first became popular during his teen years in the early 2010s among high school students from Chicago's South Side. In 2012, his popular local single "I Don't Like" was remixed by rapper Kanye West and reached the Billboard Rap Top 20, further raising Cozart's profile. A bidding war between major labels resulted in Keef signing with Interscope. His debut album Finally Rich was released in December 2012, and featured the singles "I Don't Like" and "Love Sosa", which would popularize the Chicago rap subgenre drill.

Lathan Moses Stanley Echols, known professionally as Lil Mosey, is an American rapper, singer and songwriter. He rose to fame in late 2017 with the release of his single "Pull Up". Mosey's debut studio album Northsbest (2018) included his first Billboard Hot 100 charting single, "Noticed". His second studio album, Certified Hitmaker (2019), peaked at number 12 on the US Billboard 200. In 2020, Mosey released the highest-charting single of his career, "Blueberry Faygo", which peaked at number 8 on the Billboard Hot 100.

Lorin Varencove Maazel was an American conductor, violinist and composer. He began conducting at the age of eight and by 1953 had decided to pursue a career in music. He had established a reputation in the concert halls of Europe by 1960 but, by comparison, his career in the U.S. progressed far more slowly. He served as music director of The Cleveland Orchestra, Orchestre National de France, Pittsburgh Symphony Orchestra, Bavarian Radio Symphony Orchestra, and the New York Philharmonic, among other posts. Maazel was well-regarded in baton technique and possessed a photographic memory for scores. Described as mercurial and forbidding in rehearsal, he mellowed in old age.

Kyle Orlando Massey, also known mononymously as Massey, is an American actor, rapper, and singer from Atlanta, Georgia. He starred in the Disney Channel sitcoms That's So Raven and its spin-off Cory in the House, in which he played Cory Baxter. Massey starred in the Disney Channel Original Movie Life Is Ruff. Massey has released several rap songs for Walt Disney Records and Hollywood Records. He provided the voice of Milo in the Disney animated series Fish Hooks and was the runner-up on the 11th season of ABC's Dancing with the Stars. He is the younger brother of actor Christopher Massey.

Francisco Muniz IV is an American actor, race-car driver and musician. He is best known for playing the title character in the Fox television family sitcom Malcolm in the Middle, which earned him an Emmy Award nomination and two Golden Globe Award nominations. He is also known for his film roles in Deuces Wild (2002), Big Fat Liar (2002), Agent Cody Banks (2003), and Racing Stripes (2005). At the height of his fame, he was considered one of the most popular child actors and in 2003, "one of Hollywood's most bankable teens". In 2008, Muniz put his acting career on hold to pursue an open-wheel racing career, and competed in the Atlantic Championship. From 2012 to 2014, he was a drummer in the band Kingsfoil.

Alissa Musto is an American singer, pianist and songwriter. As a child prodigy, she received national attention for her piano performances at a young age, winning piano competitions while placed in older divisions and debuting on the national series, America's Most Talented Kid at 9 years old. She is best known for being crowned Miss Massachusetts 2016 and competing at the 2017 Miss America Pageant, where placed in the top 15. Musto's musical style has been described as “hauntingly beautiful”, “captivating”, “poignant, authentic” and “the millennial ballad of the century”, while she has been critically praised as a “jazzy-folk songwriting genius” and “your generation’s Billy Joel”.

Dika Newlin was a composer, pianist, professor, musicologist, and punk rock singer. She received a Ph.D. from Columbia University at the age of 22. She was one of the last living students of Arnold Schoenberg, a Schoenberg scholar and a professor at Virginia Commonwealth University in Richmond from 1978 to 2004. She performed as an Elvis impersonator and played punk rock while in her seventies in Richmond, Virginia.

Matthew Grau, known professionally as Matt Ox, is an American rapper from Philadelphia. He is best known for his single "Overwhelming" (2017), which has since reached nearly 30 million views on YouTube, and for his feature on "$$$" with XXXTentacion released in March 2018, which has achieved more than 100 million plays on Spotify. His debut album, OX, came out in October 2018.

Frank Isaac Robinson, known in his early musical career as Sugar Chile Robinson, is an American jazz pianist and singer who became famous as a child prodigy.

Matthew "Matt" Savage is an American autistic savant musician. Born in Sudbury, Massachusetts, he is the son of Diane and Lawrence "Larry" Savage.

Philippa Duke Schuyler was an American child prodigy, pianist, author, and journalist. The daughter of black journalist George Schuyler and Josephine Schuyler, a white Texan heiress, Schuyler became famous in the 1930s as a result of her talent, intellect, mixed race parentage, and the eccentric methods employed by her mother to bring her up.

Eve Marie Shahoian is an American classical crossover and jazz singer-songwriter. She performs as 'Eve Marie' or 'Eve Shahoian' and is the creator-composer of the album Waiting for You.

DeAndre Cortez Way, better known as Soulja Boy Tell 'Em or simply Soulja Boy, is an American rapper, record producer, actor, streamer and entrepreneur. In September 2007, his debut single "Crank That " peaked at number 1 on the U.S. Billboard Hot 100. The single was initially self-published to the internet, and later became a number-one hit in the United States for seven non-consecutive weeks starting in September 2007. On August 17, Way was listed at number 18 on the Forbes list of Hip-Hop Cash Kings of 2010 for earning $7 million that year.

Shelby E. Starner was an American singer-songwriter and musician. She signed a record deal with Warner Bros. Records in 1997, releasing her official debut single, "Don't Let Them" two years later. Starner released her debut studio album, From in the Shadows, later in 1999, but it was not commercially successful. In 2000, Starner worked on a second album; it was never released. Unhappy with Warner Bros. Records, Starner ended her contract. In June 2003, Starner died suddenly at her home due to complications from bulimia nervosa.

Tione Jayden Merritt, known professionally as Lil Tjay, is an American rapper, singer, and songwriter from New York City. Born and raised in the Bronx, his musical career began in 2017. He is best known for his singles "F.N" and "Brothers", as well as his collaboration with Polo G, "Pop Out", which peaked at number 11 on the Billboard Hot 100. His debut studio album, True 2 Myself (2019), peaked at number 5 on the US Billboard 200.

Derek Trucks is an American guitarist, songwriter, and founder of the Grammy Award-winning The Derek Trucks Band. He became an official member of The Allman Brothers Band in 1999. In 2010, he formed the Tedeschi Trucks Band with his wife, blues singer/guitarist Susan Tedeschi. His musical style encompasses several genres and he has twice appeared on Rolling Stone's list of 100 Greatest Guitarists of All Time. He is the nephew of Butch Trucks, drummer for the Allman Brothers.

Marlana Danieal VanHoose is an American contemporary Christian singer. She achieved fame by singing the National Anthem at major professional sporting events.

Thomas "Blind Tom" Wiggins was an American musical prodigy on the piano. He had numerous original compositions published and had a lengthy and largely successful performing career throughout the United States. During the 19th century, he was one of the best-known American performing pianists and one of the best-known African-American musicians. Although he lived and died before autism was described, he is now regarded as an autistic savant.