William Emerson Arnett is a Canadian actor, voice actor, comedian and producer. He is best known for his role as BoJack Horseman in the Netflix series of the same name and George Oscar "Gob" Bluth II in the Fox/Netflix series Arrested Development, receiving a nomination for Primetime Emmy Award for Outstanding Supporting Actor in a Comedy Series. He has appeared in films such as Blades of Glory (2007), Hot Rod (2007), When in Rome (2010), Teenage Mutant Ninja Turtles (2014), and Teenage Mutant Ninja Turtles: Out of the Shadows (2016). His performance as Devon Banks in 30 Rock earned him four Primetime Emmy Award for Outstanding Guest Actor in a Comedy Series nominations.

Daniel Edward Aykroyd, is a Canadian actor, producer, comedian, musician, and filmmaker who was an original member of the "Not Ready for Prime Time Players" on Saturday Night Live (1975–1979). A musical sketch he performed with John Belushi on SNL, the Blues Brothers, turned into an actual performing band and then the 1980 film The Blues Brothers.

Ben Blue was a Canadian-American actor and comedian.

Fulton Burley was a Canadian performer, most widely known for his work in Disneyland. Born in Toronto, Ontario, and raised in Windsor, Ontario, Canada, Fulton came to the United States in 1943 after a telephone audition landed him the singing lead in Billy Rose's Diamond Horseshoe Revue on Broadway. He later marveled at his "Irish" luck saying, "The peculiar thing is I was at the Golden Horseshoe for 25 years, and I had started [my professional career] at the Diamond Horseshoe."

Brent Leroy Butt is a Canadian actor, comedian, and screenwriter. He is best known for his role as Brent Leroy on the CTV sitcom Corner Gas, which he created. He also created the television series Hiccups and wrote the 2013 film No Clue.

John Franklin Candy was a Canadian actor and comedian known mainly for his work in Hollywood films. Candy rose to fame as a member of the Toronto branch of the Second City and its Second City Television (SCTV) series, and through his appearances in comedy films including Stripes, Splash, Cool Runnings, Summer Rental, Home Alone, The Great Outdoors, Spaceballs, and Uncle Buck, as well as more dramatic roles in Only the Lonely and JFK. One of his most renowned onscreen performances was as Del Griffith, the talkative shower-curtain ring salesman in the John Hughes comedy Planes, Trains and Automobiles. In addition to his work as an actor, Candy was a co-owner of the Toronto Argonauts of the Canadian Football League from 1991 until his death, and the team won the 1991 Grey Cup under his ownership. Candy died of a heart attack in 1994 at the age of 43. His final two films, Wagons East and Canadian Bacon, are dedicated to his memory.

James Eugene Carrey is a Canadian-American actor, comedian, writer, producer, and artist. Known for his energetic slapstick performances, Carrey first gained recognition in 1990 after landing a regular role in the American sketch comedy television series In Living Color. His first leading roles in motion pictures came with Ace Ventura: Pet Detective (1994), The Mask (1994), Dumb and Dumber (1994), and Ace Ventura: When Nature Calls (1995), as well portraying the Riddler in Batman Forever (1995), and the lead role in Liar Liar (1997).

Gavin Crawford is a Canadian comedian and actor, best known for The Gavin Crawford Show and This Hour Has 22 Minutes.

Yvon Deschamps, CQ is a Quebec author, actor, comedian and producer best known for his monologues. His social-commentary-tinged humour propelled him to prominence in Quebec popular culture in the 1970s and 1980s. A long time comedian and still active, Deschamps is now perceived as one of the greatest in Quebec history.

Jacques Desrosiers was a Québécois Canadian singer and actor. Desrosiers was best known for playing the clown Patof in the Canadian television series Patofville. He was born in Montreal, Quebec.

Michael Andrew Fox, known professionally as Michael J. Fox, is a Canadian-American former actor, comedian, author, film producer, and activist with a film and television career spanning from the 1970s. He starred in the Back to the Future trilogy in which he portrayed Marty McFly. On television, he played Alex P. Keaton on the American sitcom Family Ties (1982–1989) and Mike Flaherty on the ABC sitcom Spin City (1996–2000). He has won five Primetime Emmy Awards, four Golden Globe Awards, a Grammy Award, and two Screen Actors Guild Awards.

Michael Thomas Green is a Canadian-American comedian and actor. Known for shock comedy, he found mainstream prominence via his MTV show, The Tom Green Show (1994–2000). Green has also played in the Hollywood films Road Trip (2000), Charlie's Angels (2000), Freddy Got Fingered, Stealing Harvard (2002) and Shred (2008). He was briefly married to actress Drew Barrymore (2001–2002), who co-starred with him in Charlie's Angels and Freddy Got Fingered.

Muriel Guilbault was a Canadian actress and comedian. She signed the Refus Global, an artistic manifesto published in 1948, with the support of fifteen co-signers including painters Jean-Paul Riopelle, Claude Gauvreau, Pierre Gauvreau, Marcel Barbeau and Marcelle Ferron. She was the sister of actress Dyne Mousso.

Philip Edward Hartman was a Canadian-American actor, comedian, screenwriter, and graphic designer. He was born in Brantford, Ontario, Canada. His family moved to the United States when he was ten years old. After graduating from California State University, Northridge, with a degree in graphic arts, Hartman designed album covers for bands including Poco and America. In 1975, Hartman joined the comedy group The Groundlings, where he helped Paul Reubens develop his character, Pee-wee Herman. Hartman co-wrote the film Pee-wee's Big Adventure and made recurring appearances as Captain Carl on Reubens's show Pee-wee's Playhouse.

Jeremy Hotz is a Canadian–American actor and stand-up comedian. Hotz won a Gemini Award for his role on the television series The Newsroom in 1997. He has appeared on Comedy Central Presents, the Just For Laughs comedy festival, the Late Show with David Letterman, and The Tonight Show with Jay Leno. He has also worked as a staff writer for Paramount's The Jon Stewart Show and has appeared in various American and Canadian motion pictures including: My Favorite Martian, Speed 2: Cruise Control, and Married Life.
Ron James is a Canadian stand-up comedian.

Eugene Levy CM is a Canadian actor, comedian, producer, director, and writer. From 1976 until 1984, he appeared in the Canadian television sketch comedy series SCTV. He is also well known for works such as the American Pie series of movies and the Canadian sitcom Schitt's Creek. He often plays flustered and unconventional figures. He is a regular collaborator of actor-director Christopher Guest, appearing in and co-writing four of his films, commencing with Waiting for Guffman (1996).

Norman Gene Macdonald is a Canadian stand-up comedian, writer, and actor, known for his deadpan style. Early in his career, he wrote for the sitcom Roseanne, and made guest appearances on shows such as The Drew Carey Show and NewsRadio. Macdonald was then a cast member on Saturday Night Live (SNL) for five years, including anchoring the Weekend Update segment for three seasons. After leaving SNL, he starred in the 1998 film Dirty Work and in his own sitcom, The Norm Show, from 1999 to 2001.

Howie Michael Mandel II is a Canadian comedian, television personality, screenwriter, actor, voice actor, producer, director, entrepreneur, game show host, and author. He hosted the CNBC game show Deal or No Deal, as well as the show's daytime and Canadian-English counterparts. In 1987, Mandel starred alongside Amy Steel in the comedy film Walk Like a Man. From 1982 to 1988, Mandel played rowdy ER intern Dr. Wayne Fiscus on the NBC medical drama St. Elsewhere. He also created, voiced, and starred in the FOX's children's cartoon Bobby's World, and he judges on NBC's America's Got Talent.
Richard Vincent "Rick" Mercer is a Canadian comedian, television personality, political satirist and author. He is best known for his work on the CBC Television comedy shows This Hour Has 22 Minutes and Rick Mercer Report. He is the author of three books, based on content from the television shows. Mercer has received more than 25 Gemini Awards for his work on television.

Colin Andrew Mochrie is a Scottish-born Canadian actor, writer, producer and improvisational comedian, best known for his appearances on the British and US versions of the improvisational TV show Whose Line Is It Anyway?

John Morgan was a Welsh-born Canadian comedian.

Michael John Myers, OC is a British-Canadian actor, comedian, screenwriter, producer and director known for his run as a performer on Saturday Night Live from 1989 to 1995 and for playing the title roles in the Wayne's World, Austin Powers and Shrek film franchises. He made his directorial debut with the documentary Supermensch: The Legend of Shep Gordon (2013). He semi-retired from acting in 2012, though he had supporting roles in Terminal and Bohemian Rhapsody.

Rose-Alma Ouellette also known by her stage name La Poune was a Quebec actress, comedian, theatre manager and artistic director. Ouellette was born to François Ouellette and Josephine Lasanté in the faubourg à M’lasse, a working-class neighbourhood in Montréal, Quebec. In her teens, she dropped out of school and worked at a shoe factory in order to provide income for her large family. In the later part of her career, she appeared in film and on television, but she is most remembered for her work on stage. She is known as the first woman ever to have directed two individual playhouses in North America.

Russell Dominic Peters is a Canadian stand-up comedian, actor, and producer. He began performing in Toronto in 1989 and won a Gemini Award in 2008. In 2013, he was number three on Forbes' list of the world's highest-paid comedians, and became the first comedian to get a Netflix stand-up special. He also won the Peabody Award and the International Emmy Award for Best Arts Programming for producing Hip-Hop Evolution (2016). He lives in Los Angeles.

Seth Aaron Rogen is a Canadian actor, comedian, writer, producer, and director. Having begun as a stand-up comedian in Vancouver, he moved to Los Angeles for a part in Judd Apatow's series Freaks and Geeks, and then got a part on the sitcom Undeclared, which also hired him as a writer. After landing his job as a staff writer on the final season of Da Ali G Show, Apatow guided him toward a film career. As a staff writer, he was nominated for a Primetime Emmy Award for Outstanding Writing for a Variety Series.

Morton Lyon Sahl is an American comedian, actor, and social satirist, considered the first modern stand-up comedian since Will Rogers. Sahl pioneered a style of social satire which pokes fun at political and current event topics using improvised monologues and only a newspaper as a prop.

Martin Hayter Short is a Canadian–American actor, comedian, singer, and writer. He is known for his work on the television programs SCTV and Saturday Night Live. He has starred in comedy films such as Three Amigos (1986), Innerspace (1987), Three Fugitives (1989), Father of the Bride (1991), Pure Luck (1991), Captain Ron (1992), Father of the Bride Part II (1995), Mars Attacks! (1996), Jungle 2 Jungle (1997), and The Santa Clause 3: The Escape Clause (2006). Short created the characters Jiminy Glick and Ed Grimley.

Frank Shuster, was a Canadian comedian best known as a member of the comedy duo Wayne and Shuster, alongside Johnny Wayne.

Steven Smith Jr., is a Canadian actor, writer and comedian. He is best known as the co-creator and star of the sketch comedy show The Red Green Show, for which he portrayed the title character.

Tabitha St. Germain, formerly known as Paulina Gillis Germain and also known as Tabitha or Kitanou St. Germain, is a Canadian actress, comedian and singer. She is known for a variety of roles across many different shows.

David Steinberg is a Canadian comedian, actor, writer, director, and author. At the height of his popularity, during the late 1960s and early 1970s, he was one of the best-known comics in the United States. He appeared on The Tonight Show Starring Johnny Carson more than 130 times and served as guest host 12 times, the youngest person ever to guest-host. Steinberg directed several films and episodes of television situation comedies, including Seinfeld, Friends, Mad About You, Curb Your Enthusiasm, The Golden Girls, and Designing Women.

Ryan Lee Stiles is an American-Canadian actor, comedian, and producer whose work is often associated with improvisational comedy. He is best known for his work on the original British series and American version of Whose Line Is It Anyway?, and the role of Lewis Kiniski on The Drew Carey Show. He also played Herb Melnick on the CBS comedy Two and a Half Men and was a performer on the show Drew Carey's Improv-A-Ganza.

Fannie Tremblay, the stage name of Stéphanie Massey, was a Canadian performer based in Quebec.

William Allan Van Evera, known by the stage name Billy Van, was a Canadian comedian, actor, and singer.

Johnny Wayne was a Canadian comedian and comedy writer best known for his work as part of the comedy duo Wayne and Shuster alongside Frank Shuster.