
Grace Banu is a Dalit and transgender activist. She was the first transgender person to be admitted to an engineering college in the state of Tamil Nadu. As of 2014, she discontinued her studies at Sri Krishna College of Engineering. She lives in the Thoothukudi district, Tamil Nadu.
Danielle Bunten Berry, also known as Dan Bunten, was an American game designer and programmer, known for the 1983 game M.U.L.E., one of the first influential multiplayer games, and 1984's The Seven Cities of Gold.

Lynn Ann Conway is an American computer scientist, electrical engineer, inventor, and transgender activist.

Kate Helen Craig-Wood is a British IT entrepreneur and the co-founder and managing director of Memset Dedicated Hosting. She has received a number of awards, including being listed 4th among the 25 most influential women in UK IT in 2012. Craig-Wood is a transgender woman, and she is known for promoting energy efficiency in IT, women in IT, and transgender acceptance.

Coraline Ada Ehmke is a software developer and open source advocate based in Chicago, Illinois. She began her career as a web developer in 1994 and has worked in a variety of industries, including engineering, consulting, education, advertising, healthcare, and software development infrastructure. She is known for her work in Ruby, and in 2016 earned the Ruby Hero award at RailsConf, a conference for Ruby on Rails developers. She is also known for her social justice work and activism, the creation of Contributor Covenant, and promoting the widespread adoption of codes of conduct for open source projects and communities.

Ashawna Hailey was among the creators of the HSPICE program, which many electronic design companies worldwide use to simulate the designed electronic circuits. Her company, Meta-Software, which was behind the commercialization of SPICE, produced compound annual growth rate in excess of 25–30 percent every year for 18 years, and had eventually become part of Synopsys, which calls HSPICE "the 'gold standard' for accurate circuit simulation". In 1973 she was part of the team who created Advanced Micro Devices' first microprocessor, the Am9080, by reverse-engineering Intel 8080, and in 1974, AMD's first nonvolatile memory, the 2702 2048-bit EPROM. Earlier, she, with others, built the launch sequencer for the Sprint Anti-Ballistic Missile System for Martin Marietta.

Veda Hlubinka-Cook is a co-founder of Metaweb. She was a video game programmer at Broderbund in the 1980s. As Robert Cook, she designed and wrote the games Gumball and D/Generation; was the model for one of the characters in Jordan Mechner's game Prince of Persia; and was technical director for The Last Express. She came out as transgender in 2017.

Mary Ann Horton, is a Usenet and Internet pioneer. Horton contributed to Berkeley UNIX (BSD), including the vi editor and terminfo database, created the first email attachment tool uuencode, and led the growth of Usenet in the 1980s.

Porpentine Charity Heartscape is a video game designer, new media artist, writer and curator based in Oakland, California. She is primarily a developer of hypertext games and interactive fiction mainly built using Twine. She has been awarded a Creative Capital grant, a Rhizome.org commission, the Prix Net Art, and a Sundance Institute's New Frontier Story Lab Fellowship. Her work was included in the 2017 Whitney Biennial. She was an editor for freeindiegam.es, a curated collection of free, independently produced games. She was a columnist for online PC gaming magazine Rock, Paper, Shotgun.
Allucquére Rosanne "Sandy" Stone is an American academic theorist, media theorist, author, and performance artist. She is currently Associate Professor and Founding Director of the Advanced Communication Technologies Laboratory (ACTLab) and the New Media Initiative in the department of Radio-TV-Film at the University of Texas at Austin. Concurrently she is Wolfgang Kohler Professor of Media and Performance at the European Graduate School EGS, senior artist at the Banff Centre, and Humanities Research Institute Fellow at the University of California, Irvine. Stone has worked in and written about film, music, experimental neurology, writing, engineering, and computer programming. Stone is transgender and is considered a founder of the academic discipline of transgender studies. She has been profiled in ArtForum, Wired, Mondo 2000, and other publications, and been interviewed for documentaries like Traceroute.

Audrey Tang is a Taiwanese free software programmer and Taiwan's Digital Minister, who has been described as one of the "ten greats of Taiwanese computing personalities". In August 2016, they were invited to join the Taiwan Executive Yuan as a minister without portfolio, making them the first transgender and the first non-binary official in the top executive cabinet. Tang has identified as "post-gender" and accepts "whatever pronoun people want to describe [them] with online."

Maddy Thorson is a Canadian video game developer, known as one of the lead creators for the video games TowerFall and Celeste, developed under their studio Matt Makes Games. Since September 2019, Thorson has effectively shut down Matt Makes Games to relaunch their team under Extremely OK Games.

Brianna Titone is an American politician and scientist, currently serving as a member of the Colorado House of Representatives from the 27th district. She serves in the 72nd Colorado General Assembly and is the first openly transgender state legislator elected in Colorado and the 4th elected in the United States.

Justine Alexandra Roberts Tunney is a software developer, a former Occupy movement activist and a blogger.

Sophie Mary Wilson is an English computer scientist, who helped design the BBC Micro and ARM architecture.