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Deuterated solvents are a group of compounds where one or more hydrogen atoms are substituted by deuterium atoms.

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Deuterated acetone ((CD3)2CO), also known as Acetone-D6, is a form (called an isotopologue) of acetone (CH3)2CO in which the hydrogen atom ("H") is replaced with deuterium (heavy hydrogen) isotope ("D"). Deuterated acetone is a common solvent used in NMR spectroscopy.

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Deuterated benzene (C6D6) is an isotopologue of benzene (C6H6) in which the hydrogen atom ("H") is replaced with deuterium (heavy hydrogen) isotope ("D"). Deuterated benzene is a common solvent used in NMR spectroscopy.

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Deuterated DMSO, also known as dimethyl sulfoxide-d6, is an isotopologue of dimethyl sulfoxide (DMSO, (CH3)2S=O)) with chemical formula ((CD3)2S=O) in which the hydrogen atoms ("H") are replaced with their isotope deuterium ("D"). Deuterated DMSO is a common solvent used in NMR spectroscopy.

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Deuterated ethanol (C2D5OD) is a form (called an isotopologue) of ethanol (C2H5OH) in which the hydrogen atom ("H") is replaced with deuterium (heavy hydrogen) isotope ("D"). Deuterated ethanol is an uncommon solvent used in NMR spectroscopy.

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Deuterated tetrahydrofuran (d8-THF), is a colourless, organic liquid at standard temperature and pressure. This heterocyclic compound has the chemical formula C4D8O, and is an isotopologue of tetrahydrofuran. Deuterated THF is used as a solvent in NMR spectroscopy, though its expense can often be prohibitive.

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Heavy water is a form of water that contains only deuterium rather than the common hydrogen-1 isotope that makes up most of the hydrogen in normal water. The presence of the heavier hydrogen isotope gives the water different nuclear properties, and the increase of mass gives it slightly different physical and chemical properties when compared to normal water.