
Act Now to Stop War and End Racism (ANSWER), also known as International A.N.S.W.E.R. and the ANSWER Coalition, is a United States–based protest umbrella group consisting of many antiwar and civil rights organizations. Formed in the wake of the September 11th attacks, ANSWER has since helped to organize many of the largest anti-war demonstrations in the United States, including demonstrations of hundreds of thousands against the Iraq War. The group has also organized activities around a variety of other issues, ranging from the Israel/Palestine debate to immigrant rights to Social Security to the extradition of Luis Posada Carriles.
Action for Boston Community Development (ABCD) is an anti-poverty, community development and human services organization founded in 1961 as Boston Community Development Program (BCDP) in Boston, Massachusetts and incorporated as Action for Boston Community Development in 1962, serving as a prototype for urban “human renewal” agencies.

The American Civil Liberties Union (ACLU) is a nonprofit organization founded in 1920 "to defend and preserve the individual rights and liberties guaranteed to every person in this country by the Constitution and laws of the United States". The ACLU works through litigation and lobbying and it has over 1,200,000 members and an annual budget of over $300 million. Local affiliates of the ACLU are active in all 50 states, the District of Columbia, and Puerto Rico. The ACLU provides legal assistance in cases when it considers civil liberties to be at risk. Legal support from the ACLU can take the form of direct legal representation or preparation of amicus curiae briefs expressing legal arguments when another law firm is already providing representation.

The American Immigration Lawyers Association (AILA), founded on October 14, 1946, is a voluntary bar association of over 15,000 attorneys and law professors who practice and teach immigration law. AILA member attorneys represent U.S. families seeking permanent residence for close family members, as well as U.S. businesses seeking talent from the global marketplace. AILA members also represent foreign students, entertainers, athletes, and asylum seekers, often on a pro bono basis. AILA is a nonpartisan, not-for-profit organization that provides continuing legal education, information, professional services, and expertise through its 38 chapters and over 50 national committees. Its national headquarters are in Washington, D.C.

The American Solidarity Party (ASP), formerly the Christian Democratic Party USA, is a Christian democratic political party in the United States. It was founded in 2011 and officially incorporated in 2016. The party has a Solidarity National Committee (SNC) and has numerous active state and local chapters. Brian Carroll was the party’s nominee in the 2020 presidential election.

The Audre Lorde Project is a Brooklyn, New York-based organization for LGBT people of color. The organization concentrates on community organizing and radical nonviolent activism around progressive issues within New York City, especially relating to LGBT communities, AIDS and HIV activism, pro-immigrant activism, prison reform and organizing among youth of color. It is named for the lesbian-feminist poet and activist Audre Lorde and was founded in 1994.
California Coalition for Immigration Reform (CCIR) was a Huntington Beach, California-based political advocacy group devoted to immigration reduction, with an emphasis on combating illegal immigration to the United States. According to the organization's website, its objectives were to "promote and expand citizen and legal resident awareness by a practical, effective communication network" and to "mobilize citizens and legal residents to support elected representatives and legislation" who favor immigration reduction.

The Coalition for Comprehensive Immigration Reform (CCIR), also known as CCIR/NAOC or New American Opportunity Campaign (NAOC) is a non-profit immigrant rights advocacy organization based in Washington, DC, established in 2003 to pass comprehensive immigration reform. It was instrumental in the 2004 Immigrant Workers Freedom Ride, modeled after the Freedom Rides of the Civil Rights Movement and acts as an umbrella organization for a number of national and local immigrant rights organizations for advocacy and coalition building.

The Council of Conservative Citizens is an American white supremacist organization. Founded in 1985, it advocates white nationalism, and supports some paleoconservative causes. In the organization's statement of principles, it states that they "oppose all efforts to mix the races of mankind".

The Federation for American Immigration Reform (FAIR) is a non profit, anti-immigration organization in the United States. The group publishes position papers, organizes events, and runs campaigns in order to advocate for changes in U.S. immigration policy. The Southern Poverty Law Center classifies FAIR as a hate group with close ties to white supremacist groups.

The Health Initiative of the Americas is a Latino program focusing mainly on migrant and immigrant health issues. It is part of the School of Public Health at the University of California, Berkeley (UCB).

Indivisible is a progressive movement in the United States initiated in 2016 as a reaction to the election of Donald Trump as President of the United States. The movement began with the online publication of a handbook written by Congressional staffers with suggestions for peacefully but effectively resisting the move to the right in the executive branch of the United States government under the Trump administration that was widely anticipated and feared by progressives. According to Peter Dreier, the goal of Indivisible is to "save American democracy" and "resume the project of creating a humane America that is more like social democracy than corporate plutocracy."

The Minuteman Civil Defense Corps was a volunteer group at one time headed by Chris Simcox and dedicated to preventing illegal crossings of the United States border. Arguing that the government is insufficiently concerned with securing the U.S. border, they have organized several state chapters, with the intention of providing law enforcement agencies with evidence of immigration law violations. The group was one of several that emerged for the proliferation of civilian border patrol groups at the US-Mexico border. It is shown that the emergence of these groups can be linked, on the one hand, to an increasing criminalization and securitization of immigration.Simcox states that the group merely reports incidents to law enforcement, and does not directly confront immigrants. There is a standard operating procedure (SOP) that must be followed by Minutemen volunteers. Rules include not speaking to, approaching, gesturing towards or having physical contact in any way with any suspected border crossers they may see. The organization has been criticized as being a right-wing militia.

The Minuteman Project was an organization which was founded in the United States in August 2004 by a group of private individuals who sought to extrajudicially monitor the United States–Mexico border's flow of illegal immigrants. Founded by Jim Gilchrist and Chris Simcox, the organization's name is derived from the name of the Minutemen, militiamen who fought in the American Revolution. The Minuteman Project describes itself as "a citizens' Neighborhood Watch on our border", and it has attracted the attention of the media due to its focus on the issue of illegal immigration.

Negative Population Growth is an organization in the United States, founded in 1972.

People For the American Way, or PFAW is a progressive advocacy group in the United States. Organized as a 501(c)(4) non-profit organization, PFAW was registered in 1981 by the television producer Norman Lear, a self-described "liberal" who founded the organization in 1980 to challenge the Christian right agenda of the Moral Majority.

Save Our State (SOS) is an activist organization opposed to illegal immigration in Southern California. The group also has a chapter in Northern California. The organization's methodology revolves around the 'transference of pain' and it has been described as a hate group by the Southern Poverty Law Center.

The United States Chamber of Commerce (USCC) is the largest lobbying group in the United States, representing over three million businesses and organizations. The group was founded in April 1912 out of local chambers of commerce at the urging of President William Howard Taft and his Secretary of Commerce and Labor Charles Nagel. It was Taft's belief that the "government needed to deal with a group that could speak with authority for the interests of business".

The United States India Political Action Committee is a political action committee based in Washington, D.C. Since its founding in 2002 by businessman Sanjay Puri, USINPAC has described its goal as "working closely with other Indian-American organizations to promote fair and balanced policies, and create a platform to enable the entry of Indian Americans in the political process." Particular issues of note have related to legal immigration, counter-terrorism, business relations, global health, religious freedom, education, and US-India trade. USINPAC has also donated significant funding to the political campaigns of both Democratic and Republican politicians, and past Senate candidates supported by USINPAC include Aruna Miller, Aneesh Chopra, Vivek Kundra, and Kesha Ram among others. USINPAC is involved with the annual US business delegation to India, and has periodically held briefings for members of the United States Congress and the United States House of Representatives. An active proponent of the H-1B Visa Program between 2003 and 2008, USINPAC has also supported the U.S.-India Civil Nuclear Agreement, the Hyde Act, the Section 123 Agreement, the Domestic Prosperity and Global Freedom Act, and hate-crime expansions to the Local Law Enforcement Enhancement Act (LLEEA), among others.