
The Space Shuttle orbiter is the spaceplane component of the Space Shuttle, a partially reusable orbital spacecraft system that was part of the discontinued Space Shuttle program. Operated from 1977 to 2011 by NASA, the U.S. space agency, this vehicle could carry astronauts and payloads into low Earth orbit, perform in-space operations, then re-enter the atmosphere and land as a glider, returning its crew and any on-board payload to the Earth.

Space Shuttle Atlantis is a Space Shuttle orbiter vehicle which belongs to the National Aeronautics and Space Administration (NASA), the spaceflight and space exploration agency of the United States. Manufactured by the Rockwell International company in Southern California and delivered to the Kennedy Space Center in Eastern Florida in April 1985, Atlantis is the fourth operational and the second-to-last Space Shuttle built. Its maiden flight was STS-51-J from 3 to 7 October 1985.

Space Shuttle Challenger (OV-099) was a Space Shuttle orbiter manufactured by Rockwell International and operated by NASA. Named after the commanding ship of a nineteenth-century scientific expedition that traveled the world, Challenger was the second Space Shuttle orbiter to fly into space after Columbia, and launched on its maiden flight in April 1983. It was destroyed in January 1986 soon after launch in an accident that killed all seven crewmembers aboard. Initially manufactured as a test article not intended for spaceflight, it was utilized for ground testing of the Space Shuttle orbiter's structural design. However, after NASA found that their original plan to upgrade Enterprise for spaceflight would be more expensive than upgrading Challenger, the orbiter was pressed into operational service in the Space Shuttle program. Lessons learned from the first orbital flights of Columbia led to Challenger's design possessing fewer thermal protection system tiles and a lighter fuselage and wings. This led to it being 1,000 kilograms lighter than Columbia, though still 2,600 kilograms heavier than Discovery.

Space Shuttle Columbia (OV-102) was a Space Shuttle orbiter manufactured by Rockwell International and operated by NASA. Named after the first American ship to circumnavigate the upper North American pacific coast and the female personification of the United States, Columbia was the first of five Space Shuttle orbiters to fly in space, debuting the Space Shuttle launch vehicle on its maiden flight in April 1981. As only the second full-scale orbiter to be manufactured after the Approach and Landing Test vehicle Enterprise, Columbia retained unique features indicative of its experimental design compared to later orbiters, such as test instrumentation and distinctive black chines. In addition to a heavier fuselage and the retention of an internal airlock throughout its lifetime, these made Columbia the heaviest of the five spacefaring orbiters; around 1,000 kilograms heavier than Challenger and 3,600 kilograms heavier than Endeavour. Columbia also carried ejection seats based on those from the SR-71 during its first six flights until 1983, and from 1986 onwards carried an external scientific instrument bay on its vertical stabilizer.

Space Shuttle Discovery is one of the orbiters from NASA's Space Shuttle program and the third of five fully operational orbiters to be built. Its first mission, STS-41-D, flew from August 30 to September 5, 1984. Over 27 years of service it launched and landed 39 times, aggregating more spaceflights than any other spacecraft to date. The Space Shuttle launch vehicle has three main components: the Space Shuttle orbiter, a single-use central fuel tank, and two reusable solid rocket boosters. Nearly 25,000 heat-resistant tiles cover the orbiter to protect it from high temperatures on re-entry.

Space Shuttle Endeavour is a retired orbiter from NASA's Space Shuttle program and the fifth and final operational Shuttle built. It embarked on its first mission, STS-49, in May 1992 and its 25th and final mission, STS-134, in May 2011. STS-134 was expected to be the final mission of the Space Shuttle program, but with the authorization of STS-135, Atlantis became the last shuttle to fly.

Space Shuttle Enterprise was the first orbiter of the Space Shuttle system. Rolled out on September 17, 1976, it was built for NASA as part of the Space Shuttle program to perform atmospheric test flights after being launched from a modified Boeing 747. It was constructed without engines or a functional heat shield. As a result, it was not capable of spaceflight.