WAllergies in children are those causes, pathophsiology, treatments, management, practices and control of allergies that develop in children. Up to 40 percent of children suffer from allergic rhinitis. And children are more likely to develop allergies if one or both parents have allergies. Allergies differ between adults and children. Part of the reason for this that the respiratory system in children is smaller. The bronchi and bronchioles are narrower so even a slight decrease in diameter of these airways can have serious consequences. Many children outgrow their allergies.
WAnomalous aortic origin of a coronary artery (AAOCA) is a rare congenital heart defect in which a coronary artery inappropriately arises from the aorta, usually from the incorrect sinus of Valsalva. This anomalous coronary artery often takes an interarterial, intraconal, or intramural course, and is associated with an increased risk of sudden death in children.
WThe Antihypertensive and Lipid Lowering Treatment to Prevent Heart Attack Trial, also known as ALLHAT, was a randomized, double-blind, active-controlled study comparing at the same time, four different classes of antihypertensive drugs with the rate of coronary heart disease (CHD) events in ‘high-risk’ people with hypertension. Participants were initially randomised to chlorthalidone (diuretic) versus doxazosin, lisinopril (ACE-inhibitor), and amlodipine.
WThe British Doctors' Study was a prospective cohort study which ran from 1951 to 2001, and in 1956 provided convincing statistical proof that tobacco smoking increased the risk of lung cancer.
WThe Caerphilly Heart Disease Study, also known as the Caerphilly Prospective Study (CaPS), is an epidemiological prospective cohort, set up in 1979 in a representative population sample drawn from Caerphilly, a typical small town in South Wales, UK.
WCOSMOS is a cohort study of mobile phone use and health. The study will investigate the possible health effects of long-term use of mobile phones and other wireless technologies. It is an international study being conducted in five European countries – UK, Denmark, Sweden, Finland, the Netherlands and France. In the UK Imperial College London is carrying out this research.
WThe Dog Aging Project is a long-term biological study of aging in dogs, centered at the University of Washington. Professors Daniel Promislow and Matt Kaeberlein are the co-directors of the project. Together with Chief Veterinarian, Dr. Kate Creevy, the project primarily focuses on research to understand dog aging through the collection and analysis of big data. Additionally, there is a small component of the project that explores the use of pharmaceuticals to potentially increase life span of dogs. The project has implications for improving the life spans of humans and is an example of geroscience.
WThe European Health Examination Survey (EHES) is an ongoing series of large-scale clinical epidemiological studies. It is a cooperative effort among multiple European nations, in concert with the European Union (EU), the European Economic Area (EEA) and the European Free Trade Area (EFTA). While actual data collection is carried out through the health ministries of each participating nation, the coordination of these efforts across borders is under the jurisdiction of the European Commission's Directorate-General for Health and Food Safety.
WThe GuLF Study, or Gulf Long-term Follow-up Study, is a five-year research project examining the human-health consequences of the Deepwater Horizon oil spill in April 2010. The spill followed an explosion on a drilling rig leased by BP, the British oil company, and led to the release of over four million barrels of oil into the Gulf of Mexico, 48 miles off the coast of Louisiana in the United States.
WThe Heart Protection Study was a randomized controlled trial run by the Clinical Trial Service Unit, and funded by the Medical Research Council (MRC) and the British Heart Foundation (BHF) in the United Kingdom. It studied the use of the cholesterol lowering drug, simvastatin 40 mg and vitamin supplementation in people who were at risk of cardiovascular disease. It was led by Jane Armitage, an epidemiologist at the Clinical Trial Service Unit.
WThe Millennium Cohort Family Study, a sub-study of the Millennium Cohort Study, is a United States Department of Defense-sponsored project designed to evaluate the short- and long-term effects of the military experience on Service members and their families. Both studies are conducted at the Naval Health Research Center in San Diego, California. The research teams include uniformed officers as well as investigators from the Department of Defense and academic institutions.
WThe Millennium Cohort Study is an ongoing longitudinal cohort study headquartered at the Naval Health Research Center in San Diego, California and designed to evaluate any long-term health effects of military service, including deployments. It is the largest population-based prospective health project in US military history, currently collecting data on over 200,000 enrolled participants. Investigators that conduct the Millennium Cohort Study include uniformed and non-uniformed scientists from the Army, Navy, Air Force, Department of Veterans Affairs and academic institutions.
WP3G (Public Population Project in Genomics and Society) is a not-for-profit international consortium dedicated to facilitating collaboration between researchers and biobanks working in the area of human population genomics. P3G is member-based and composed of experts from the different disciplines in the areas of and related to genomics, including epidemiology, law, ethics, technology, biomolecular science, etc. P3G and its members are committed to a philosophy of information sharing with the goal of supporting researchers working in areas that will improve the health of people around the world.
WA randomized controlled trial is a type of scientific experiment that aims to reduce certain sources of bias when testing the effectiveness of new treatments; this is accomplished by randomly allocating subjects to two or more groups, treating them differently, and then comparing them with respect to a measured response. One group—the experimental group—receives the intervention being assessed, while the other—usually called the control group—receives an alternative treatment, such as a placebo or no intervention. The groups are monitored under conditions of the trial design to determine the effectiveness of the experimental intervention, and efficacy is assessed in comparison to the control. There may be more than one treatment group or more than one control group.
WThe Scandinavian Simvastatin Survival Study, was a multicentre, randomized, double-blind, placebo-controlled clinical trial, which provided the initial data that supported the use of the cholesterol-lowering drug, simvastatin, in people with a moderately raised cholesterol and coronary heart disease (CHD); that is people who had previously had a heart attack or angina. The study was sponsored by the pharmaceutical company Merck and enrolled 4,444 people from 94 centres in Scandinavia.
WThe Trøndelag Health Study is a cohort health study performed in the Norwegian county of Trøndelag. HUNT is considered one of the most extensive cohort studies ever conducted in any country. The HUNT Research Centre, which is responsible for collecting and providing access to the data and samples from the study, is part of the Faculty of Medicine and Health Sciences at the Norwegian University of Science and Technology (NTNU).