The Alexians, Alexian Brothers or Cellites are a Catholic religious institute or congregation specifically devoted to caring for the sick which has its origin in Europe at the time of the Black Death. They follow the Augustinian rule.

The Bethlehemite Brothers are a religious institute founded in Guatemala in 1653 and restored in 1984.

The Camillians or Clerics Regular, Ministers to the Sick are a Roman Catholic religious order, founded in 1582 by St. Camillus de Lellis (1550-1614). A large red cross was chosen by the founder as the distinguishing badge for the members of the Order to wear upon their black cassocks, which was later adopted as the international symbol of medical care. As of 2018, 1080 Camillians serve in 35 countries. They use the postnominal initials of M.I..

The Canonesses of St. Augustine of the Mercy of Jesus are a Roman Catholic religious order of canonesses who follow a semi-contemplative life and are also engaged in the ministry of caring for the sick and needy, from which they were also known as the "Hospital Sisters".

The Congregation of Divine Providence is a Catholic religious institute of women that was founded in 1851 in the Grand Duchy of Hesse by Wilhelm Emmanuel von Ketteler, Bishop of Mainz, together with Stephanie Fredericke Amalie de la Roche von Starkenfels (1812–1857), a French noblewoman. The congregation was formally recognized by the Holy See on 16 July 1935.

The Daughters of the Holy Spirit or the White Sisters are a Roman Catholic religious institute of women founded in France in 1706. The Religious Sisters of this institute are dedicated to the service of the poor and needy. The motherhouse for the congregation is in Saint-Brieuc, Brittany, France. The members of the congregation use the post-nominal initials of D.H.S. or F.S.E.

The Franciscan Hospitaller Sisters of the Immaculate Conception are members of a Roman Catholic religious institute of consecrated women, which was founded in Portugal in 1871. They follow the Rule of the Third Order Regular of St. Francis. and, as the term “hospitaller” indicates, focus their ministries on a spirit of medical care. Their charism emphasizes hospitality and service under the model of the Good Samaritan. In this congregation, the postnominal initials used after each Sister's name is "F.H.I.C."

The Franciscan Missionaries of Mary are a Roman Catholic religious institute founded by Mother Mary of the Passion at Ootacamund, then British India, in 1877. The Missionaries form an international religious congregation of women representing 79 nationalities spread over 74 countries on five continents.

The Hospital Brothers of Saint Anthony, Order of Saint Anthony or Canons Regular of Saint Anthony of Vienne, also Antonines, were a Roman Catholic congregation founded in c. 1095, with the purpose of caring for those suffering from the common medieval disease of Saint Anthony's fire.

The Medical Mission Sisters (MMS) are a religious congregation of women in the Roman Catholic Church founded in 1925 and dedicated to providing the poor of the world better access to health care. They were formerly officially known as the "Society of the Catholic Medical Missions".

The Obregonians, or the Minim Congregation of Poor Brothers Infirmarians, were a small Roman Catholic congregation of men dedicated to the nursing care of the sick, who professed the Rule of the Third Order Regular of St. Francis.

The Order of the Holy Ghost is a Roman Catholic religious order. It was founded by Guy de Montpellier in Provence for the care of the sick by groups of lay people. Pope Innocent III recognised it ca 1161–June 16, 1216. It was originally based in the Santo Spirito in Sassia in Rome. A small female remnant survives in Poland.

The Congregation of the Sisters of Charity of Jesus and Mary is a Roman Catholic religious institute founded in Ghent, Belgium. An enclosed religious order, its main apostolate is helping the needy and the sick, inspired by the work of Saint Vincent de Paul and Saint Bernard of Clairvaux.

The Sisters of Charity of Saint Vincent de Paul were founded on May 11, 1849, when the four founding Sisters of Charity arrived in Halifax, Nova Scotia, from New York City; this has been designated a National Historic Event.

The Religious Sisters of Mercy are members of a religious institute of Catholic women founded in 1831 in Dublin, Ireland, by Catherine McAuley. As of 2019, the institute has about 6200 sisters worldwide, organized into a number of independent congregations. They also started many education and health care facilities around the world.

The Sisters of St. Joseph, also known as the Congregation of the Sisters of St. Joseph and abbreviated C.S.J. or S.S.J., is a Roman Catholic religious congregation of women founded in Le Puy-en-Velay, France, in 1650. This Congregation, named for Saint Joseph, has approximately 14,000 members worldwide: about 7,000 in the United States; 2,000 in France; and are active in 50 other countries.

The Servants of Mary, Ministers to the Sick, are a Roman Catholic religious institute of women founded in Madrid, Spain, in 1851 and dedicated to the care of the sick, poor, both in clinics, hospices and through home health nursing. They were founded by Maria Soledad Torres y Acosta who was canonized by Pope Paul VI in 1970. The Religious Sisters of this congregation use the postnominal initials of S.de M.

The Ursulines, also known as the Order of Saint Ursula, is an enclosed religious order of consecrated women that branched off from the Angelines, also known as the Company of Saint Ursula, in 1572. Like the Angelines, they trace their origins to their foundress Saint Angela Merici and place themselves under the patronage of Saint Ursula. While the Ursulines took up a monastic way of life under the Rule of Saint Augustine, the Angelines operate as a secular institute. The largest group within the Ursulines is the Ursulines of the Roman Union.