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Budding Prospects is a 1984 novel by T. C. Boyle. It details the misadventure of protagonist Felix Nasmyth, who plans to get rich quick by illegally growing marijuana.

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Drop City is a 2003 novel by American author T. Coraghessan Boyle. The novel, set in 1970, describes the social evolution of a group of counter-cultural free spirits, not unlike the inhabitants of the real Drop City community in Colorado, from which the novel apparently takes its name. However, Boyle's fictional group initially live in California and later move to a remote part of Alaska, and the group shares many qualities with the real Sonoma County Morning Star commune. The novel was a finalist for the 2003 National Book Award.

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East is East is a 1990 novel by American author T. Coraghessan Boyle.

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A Friend of the Earth is a 2000 novel by T. Coraghessan Boyle. The novel is a story of environmental destruction set in 2025; as a result of global warming and the greenhouse effect, the climate has drastically changed, and, accordingly, biodiversity is a thing of the past.

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The Inner Circle is a novel by T. C. Boyle first published in 2004 about the development of sexology in the United States and about Alfred Kinsey's rise to fame during the late 1940s and early 1950s as seen through the eyes of one of his loyal assistants.

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Outside Looking In is a novel by American author T. C. Boyle. It was published on April, 9, 2019. It takes place during the Harvard LSD experiments of the early 1960s. A version of Timothy Leary appears as a character, depicted as a "blend of cheerfulness and manipulation."

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Riven Rock is a 1998 novel by American author T. Coraghessan Boyle. It concerns the life of Stanley McCormick, a son of Cyrus McCormick, inventor of the reaper, and Stanley's devoted wife, Katherine McCormick, daughter of Wirt Dexter, a prominent Chicago lawyer.

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The Road to Wellville is a 1993 novel by American author T. Coraghessan Boyle. Set in Battle Creek, Michigan, during the early days of breakfast cereals, the story includes a historical fictionalization of John Harvey Kellogg, the inventor of corn flakes.

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Talk Talk is a 2006 novel by T. C. Boyle. It concerns a young deaf woman who becomes the victim of a credit card fraud and identity theft. When the police are unwilling to help, the woman and her boyfriend attempt to track down the criminal themselves.

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The Tortilla Curtain is a novel by U.S. author T.C. Boyle, published in 1995. It is about middle-class values, illegal immigration, xenophobia, poverty, and environmental destruction. In 1997, it was awarded the French Prix Médicis Étranger prize for best foreign novel.

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Water Music is the first novel by T. C. Boyle, first published in 1981. It is a semi-fictional historical adventure novel that is set in the late 18th and early 19th century.

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When the Killing's Done is a 2011 novel by T. C. Boyle. The book is an environmental and family drama revolving around the Channel Islands of California—specifically Anacapa and Santa Cruz—and the controversy surrounding efforts by the National Park Service and its partners to eradicate invasive species and revitalize the islands' natural communities.

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The Women is a 2009 novel by T. C. Boyle. It is a fictional account of Frank Lloyd Wright's life, told through his relationships with four women: the young Montenegrin dancer Olgivanna; Miriam, the "morphine-addicted and obsessive Southern belle"; Mamah, whose life ended in a massacre at Taliesin, the home Wright built for his lovers and wives; and his first wife, Kitty, the mother of six of his children."

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World's End is a 1987 historical fiction novel by T. C. Boyle. The novel, characterized by dark satire, tells the story of several generations of families in the Hudson River Valley. It was the winner of the 1988 PEN/Faulkner Award for American Fiction.