
Abel is a fictional character in the DC Comics universe based on the biblical Abel but is altogether a different character. He is a key figure in DC's "Mystery" line of the late 1960s and 1970s while being depicted as an horror host, which he later became a part of the mature-readers imprint, Vertigo, in 1993. The Sandman comic books retconned him as part of the Dreaming. He is depicted as the brother of Cain and son of Eve.

Elaine Belloc is a fictional character in the DC/Vertigo Comics series Lucifer created by Mike Carey. Elaine was created by Carey specifically for the Lucifer series, and her character is that of a young girl with special powers who encounters Lucifer and takes part in the adventures and battles surrounding him. Artist Dean Ormston based the character of Elaine on Vertigo editor Shelly Bond, while her best friend Mona was based on Ormston's wife Fiona Stephenson.
Black Orchid is the name of four superheroines published by DC Comics. The original version of the character first appeared in Adventure Comics #428.

Cain along with his pet gargoyle, Gregory, are fictional characters that are recurring in the DC Comics universe. Cain based on the biblical Cain while being a different character altogether. Cain and Gregory are one of four human and pet companions key figures in DC's "Mystery" lineup referred to as horror hosts of the late 1960s and 1970s, which became the mature-readers imprint, Vertigo, in 1993 retconned as part of the Dreaming in the critically acclaimed Sandman comic books. He is depicted as the brother of Abel and son of Eve.

John Constantine is a fictional antihero and mystic appearing in American comic books published by DC Comics and its alternative imprint Vertigo. The character first appeared in The Saga of Swamp Thing #37, and was created by Alan Moore, Rick Veitch, Steve Bissette, and John Totleben. He serves as the lead character of the comic books Hellblazer (1988–2013), Constantine (2013–2015), Constantine: The Hellblazer (2015–2016), and The Hellblazer (2016–2018).

Corinthian is a fictional character in Neil Gaiman's comic book series The Sandman. He first appeared in The Sandman #10, which is part of the second story arc, The Doll's House. The Corinthian is a nightmare created by Dream, who destroys him in the same collection for going rogue and failing to fulfill his original design. Dream later recreates him with "some changes", though the exact nature of these changes is not explicit. His most notable physical feature is his lack of eyes: in their place, two rows of small, jagged teeth line each eye socket, which he often covers with sunglasses. He can speak, eat, see, and even respire through these mouths.

Jesse Custer is a fictional character and the protagonist of the comic book series Preacher, created by writer Garth Ennis and artist Steve Dillon, published by the Vertigo imprint of DC Comics.

Death is a character who appears in American comic books published by DC Comics. She first appeared in The Sandman vol. 2, #8, and was created by Neil Gaiman and Mike Dringenberg.

Dream is a fictional character who first appeared in the first issue of The Sandman, written by Neil Gaiman and published by DC Comics. One of the seven Endless, inconceivably powerful beings older and greater than gods, Dream is both lord and personification of all dreams and stories, all that is not in reality. He has taken many names, including Morpheus and Oneiros, and his appearance can change depending on the person who is seeing him. Dream was named the sixth-greatest comic book character by Empire Magazine. He was also named fifteenth in IGN's 100 Top Comic Book Heroes list.

Abigail Arcane Cable Holland is a fictional comic book character in the DC Comics Universe. She is the spouse/partner of Swamp Thing and the mother of Tefé Holland. Holland's psychic powers include empathy, telepathy and telekinesis. She first appeared in Swamp Thing #3 and was created by Len Wein and Bernie Wrightson.

Timothy Hunter is a fictional character, a comic book sorcerer published by DC Comics. He first appeared in The Books of Magic #1, and was created by Neil Gaiman and John Bolton.

Spider Jerusalem is a fictional character and the protagonist of the comic book Transmetropolitan, created by writer Warren Ellis and artist Darick Robertson, introduced under the now-defunct Helix imprint of DC Comics before being moved to the Vertigo imprint.

Lucifer Samael Morningstar is a character who appears in American comic books published by DC Comics. He is an adaptation of Lucifer—the Biblical fallen angel and devil of Christianity—and is one of the most powerful beings in the DC Universe. Though various versions of the Devil have been presented by DC Comics, this interpretation by Neil Gaiman debuted in The Sandman #4 in 1989. Lucifer appears primarily as a supporting character in the The Sandman and as the protagonist of the spin-off Lucifer.

Mazikeen is a fictional character in a comic book published by DC Comics. She is one of the lilim, a child of Lilith. She first appeared in Sandman #22, and was created by Neil Gaiman and Kelley Jones. Her name comes from the term "Mazzikin", invisible demons which can create minor annoyances or greater dangers according to Jewish mythology. Mazikeen makes her live appearance in the television series Lucifer by Lesley-Ann Brandt.

The Phantom Stranger is a fictional superhero of unspecified paranormal origins, who battles mysterious and occult forces in various titles published by DC Comics, sometimes under their Vertigo imprint. The character first appeared in an eponymous comics anthology published in August/September 1952.

The Saint of Killers is a fictional character who appears in the comic book series Preacher, published by Vertigo Comics in 1995. The Saint of Killers was created by writer Garth Ennis with artist Steve Dillon. The Saint is described as, "a grim, taciturn, implacable killing machine", with supernatural abilities involving divinity, immortality, and influence over Heaven and Hell. His goals typically center on bringing down individuals through destruction and death by the laws of Paradise.

Doc Strange is a Golden Age comic book superhero who originally appeared in Thrilling Comics #1 in February 1940. The character continued in Thrilling Comics until issue #64. He also appeared in America's Best Comics #1-23 and 27.

The Swamp Thing is a fictional superhero in American comic books published by DC Comics. A humanoid/plant elemental creature, created by writer Len Wein and artist Bernie Wrightson, the Swamp Thing has had several humanoid or monster incarnations in various different storylines. The character first appeared in House of Secrets #92 in a stand-alone horror story set in the early 20th century. The character then returned in a solo series, set in the contemporary world and in the general DC continuity. The character is a swamp monster that resembles an anthropomorphic mound of vegetable matter, and fights to protect his swamp home, the environment in general, and humanity from various supernatural or terrorist threats.

Titania is a fictional character, a comic book faerie published by DC Comics. She first appeared in The Sandman #19, and was created by Neil Gaiman and Charles Vess. She is inspired by and implied to be the same as Titania as the faerie queen in William Shakespeare's play A Midsummer Night's Dream.