
Are You My Mother? is a children's book by P. D. Eastman published by Random House Books for Young Readers on June 12, 1960, as part of its Beginner Books series. Based on a 2007 online poll, the National Education Association listed the book as one of its "Teachers' Top 100 Books for Children." It was one of the "Top 100 Picture Books" of all time in a 2012 poll by School Library Journal.

Astronauta – Magnetar is a 2012 Brazilian graphic novel written and illustrated by Danilo Beyruth based on the character Astronauta created by Maurício de Sousa. It is the first installment in the Graphic MSP series of graphic novels based on Maurício de Sousa characters.

Avatar: The Last Airbender – The Promise is a graphic novel in three parts written by Gene Yang and illustrated by Studio Gurihiru, the first in a series of graphic novel trilogies serving as both a continuation of the Avatar: The Last Airbender and a prequel to The Legend of Korra, both animated television series created by Michael Dante DiMartino and Bryan Konietzko. Part 1 was released on January 25, 2012, Part 2 was released on May 30, 2012 and Part 3 was released on September 26, 2012.

Batman: Earth One is a series of graphic novels published by DC Comics as part of the Earth One line. The series is written by Geoff Johns and illustrated by Gary Frank. Volume One of the series was released on July 4, 2012. Volume Two was announced for a 2013 release but postponed and, as a result, was released on May 6, 2015. Volume Three is set to be released on June 8, 2021.
Pierre-François "David" Beauchard, who uses the pen name David B., is a French comic book artist and writer, and one of the founders of L'Association.

Best Shot in the West: The Adventures of Nat Love is a 2012 graphic novel written by Patricia and Fredrick McKissack and illustrated by Randy DuBurke. It is about the life of African-American cowboy Nat Love.

Bucko is a comic written by Jeff Parker and drawn by Erika Moen. It was serialized as a webcomic in 2011–2012 before being published as a book by Dark Horse Comics on September 12, 2012. It is a comedic murder mystery story.

Building Stories is a 2012 graphic novel by American cartoonist Chris Ware. The unconventional work is made up of fourteen printed works—cloth-bound books, newspapers, broadsheets and flip books—packaged in a boxed set. The work took a decade to complete, and was published by Pantheon Books. The intricate, multilayered stories pivot around an unnamed female protagonist with a missing lower leg. It mainly focuses on her time in a three-story brownstone apartment building in Chicago, but follows her later in her life as a mother. The parts of the work can be read in any order.

Dotter of Her Father's Eyes is a 2012 graphic novel written by Mary M. Talbot with artwork by her husband, Bryan Talbot. It is part memoir, and part biography of Lucia Joyce, daughter of modernist writer James Joyce.

Drama is a graphic novel written by Raina Telgemeier, an American cartoonist, which centers on the story of Callie, a middle schooler and theater-lover who works in her school's drama production crew. While navigating seventh grade, Callie deals with tween hardship, including confusing crushes, budding friendships, and typical middle school drama. It is a coming-of-age story that explores themes of friendship, teamwork, inclusion, and determination through Callie and her relationship with the people around her.

Ed the Happy Clown is a graphic novel by Canadian cartoonist Chester Brown. Its title character is a large-headed, childlike children's clown who undergoes one horrifying affliction after another. The story is a dark, humorous mix of genres and features scatological humour, sex, body horror, extreme graphic violence, and blasphemous religious imagery. Central to the plot are a man who cannot stop defecating; the head of a miniature, other-dimensional Ronald Reagan attached to the head of Ed's penis; and a female vampire who seeks revenge on her adulterous lover who had murdered her to escape his sins.

Friends with Boys is a 2012 graphic novel and webcomic by Faith Erin Hicks. The book was first published on February 28, 2012 through First Second Books. The company, who had licensed the work prior to its release in any format, gave Hicks permission to post the book online as a webcomic prior to its publication.

Goliath (2012) is a graphic novel by Tom Gauld, published by Drawn and Quarterly. It is Gauld's first long-form book.

House of Odd is the third graphic novel featuring Dean Koontz's character Odd Thomas. It was released March 20, 2012. It is written by Landry Walker and Koontz, with illustrations by Queenie Chan in a manga style.

My Friend Dahmer is a 2012 graphic novel and memoir by artist John "Derf" Backderf about his teenage friendship with Jeffrey Dahmer, who later became a serial killer. The book evolved from a 24-page, self-published version by Derf in 2002.

No Straight Lines is an anthology of queer comics covering a 40-year period from the late 1960s to the late 2000s. It was edited by Justin Hall and published by Fantagraphics Books on August 1, 2012.

Pixies is an 2015 animated fantasy feature film released by Arcana Studio. It is based on the 2012 graphic novel of the same name. Pixies is written, produced and directed by Sean O'Reilly, the author of the graphic novel, who was nominated for the 2016 Leo Awards for best Direction in an Animation Program for his work on the film.

Prince of Cats is a 2012 graphic novel by Ronald Wimberly. The story focuses on Tybalt, a character from Romeo and Juliet, and is set in 1980s New York. After being out of print for four years, the book was re-worked and re-released in 2016.

A Bag of Marbles is a Second World War autobiographical novel by the French Jewish author Joseph Joffo. It tells the story of his flight, as a small boy, with his brother Maurice to escape from Nazi occupied France to the Zone Libre. Joffo was refused by many publishers before being encouraged by the newly founded publishing house Éditions Jean-Claude Lattès to get the help of an editor to publish the text. The book was a phenomenal best-seller, being made into a major film two years later.

Superman: Earth One is a series of graphic novels written by J. Michael Straczynski and illustrated by Shane Davis. The first volume was published in the US in October 27, 2010 by DC Comics, and in the UK in 2011 by Titan Books. Superman: Earth One was the inaugural title of the new, ongoing graphic novel series Earth One.

Trinity: A Graphic History of the First Atomic Bomb is the debut graphic novel written and illustrated by Jonathan Fetter-Vorm. It provides an account of the Manhattan Project and the atomic bombings of Hiroshima and Nagasaki, as well as mentioning the chain of events after. The title arises from the code-name, Trinity, given to the test site for the first nuclear weapon.