
Anne, first published in 1880 by author Constance Fenimore Woolson, is a work of American literary regionalism. It depicts the emotional and spiritual conflicts faced by its eponymous heroine as she leaves her home village, Mackinac Island, to seek a future as a young woman in the Northeastern United States. Her good qualities win her many suitors, but she finds hypocrisy and dysfunctional social relationships among the wealthier strata of U.S. Victorian society. Eventually she selects a suitor who, although of wealthy origins, has lost his means and is ready to accept the stolid virtues of the American working class. Anne Douglas returns with her new partner to her place of origin.

The Big Bounce is a crime novel written by Elmore Leonard, who started offering the story to publishers and film producers in the fall of 1966. However, no one would take it. It went unpublished until 1969, when it was adapted into a film version in 1969, directed by Alex March and scripted by Robert Dozier, with actor Ryan O'Neal in the lead role.

Blankety Blank: A Memoir of Vulgaria (2005) is a novel by American author D. Harlan Wilson.

Bud, Not Buddy is the second children's novel written by Christopher Paul Curtis. The first book to receive both the Newbery Medal for excellence in American children's literature, and the Coretta Scott King Award, which is given to outstanding African-American authors, Bud, Not Buddy was also recognized with the William Allen White Children's Book Award for grades 6-8.

Daddy Cool is a novel by Donald Goines that was published along with five other novels by Goines in 1974, which would also be the year Goines died. The novel would later be turned into a graphic novel.

Daughters of Eve is a 1979 novel by Lois Duncan. Incorporating feminist themes, the novel follows a group of young women who become convinced to punish their fathers by a charismatic teacher.

The House with a Clock in Its Walls is a 1973 juvenile mystery fiction novel written by John Bellairs and illustrated by Edward Gorey. It is the first in the series of twelve novels featuring the fictional American boy Lewis Barnavelt.

Jumping the Scratch is a novel by Sarah Weeks written for young adults. It was first published in 2006.

Killshot, the 1989 novel by author Elmore Leonard, tells the story of a married couple who find themselves in Cape Girardeau, Missouri while on the run from a pair of hitmen.

Laughing Whitefish is a 1965 historical novel by Justice John D. Voelker, writing under the pen name "Robert Traver". It is based on an actual trilogy of Michigan Supreme Court cases from the 1880s. The final case in the series, Kobogum v. Jackson Iron Co., established in Michigan the general rule that state courts must defer to tribal law in cases involving the internal, domestic relations of American Indians residing within their own territory.

Life in the Fat Lane is a novel for young adults written by Cherie Bennett. The novel was included among the American Library Association Best Books for Young Adults. It was published in 1998 by Delacorte Press.

The Mighty Miss Malone is a 2012 children's novel by author Christopher Paul Curtis and is a followup to his 2000 book Bud, Not Buddy. The book was released on January 10, 2012 by Wendy Lamb Books. The Mighty Miss Malone follows the character of 12-year-old African-American Deza Malone, who narrates the book.

Northwest Passage is an historical novel by Kenneth Roberts, published in 1937. Told through the eyes of primary character Langdon Towne, much of the novel follows the exploits and character of Robert Rogers, the leader of Rogers' Rangers, who were a colonial force fighting with the British during the French and Indian War.

The Oak Openings; or, The Bee Hunter is an 1848 novel by James Fenimore Cooper. The novel focuses on the activities of professional honey-hunter Benjamin Boden, nicknamed "Ben Buzz". The novel is set in Kalamazoo, Michigan's Oak Opening, a wooded prairie that still exists in part today, during the War of 1812.

Other Electricities is a novel by Ander Monson. It is Monson's first novel, and is described by him as a work of poetry, fiction and nonfiction.

The Road to Wellville is a 1993 novel by American author T. Coraghessan Boyle. Set in Battle Creek, Michigan, during the early days of breakfast cereals, the story includes a historical fictionalization of John Harvey Kellogg, the inventor of corn flakes.

The Season of the Witch is a novel by James Leo Herlihy. The story is written in the form of a journal that spans three months in the life of teenage runaway Gloria Glyczwycz during the autumn of 1969.

Second Heaven is a novel written by Judith Guest, published in 1983. ISBN 0-451-12499-5 ISBN 0670628301

Song of Solomon is a 1977 novel by American author Toni Morrison, her third to be published. It follows the life of Macon "Milkman" Dead III, an African-American man living in Michigan, from birth to adulthood.

Station Eleven is a 2014 novel by Emily St. John Mandel. It is Mandel's fourth novel. The novel takes place in the Great Lakes region before and after a fictional swine flu pandemic, known as the "Georgia Flu", has devastated the world, killing most of the population. It won the Arthur C. Clarke Award in 2015.

The Time Traveler's Wife is the debut novel by the American author Audrey Niffenegger, published in 2003. It is a love story about Henry, a man, with a genetic disorder that causes him to time travel unpredictably, and about Clare, his wife, an artist, who has to cope with his frequent absences and dangerous experiences of reappearing in odd places. Niffenegger, who was frustrated in love when she began the novel, wrote the story as a metaphor for her failed relationships. The tale's central relationship came to Niffenegger suddenly and subsequently supplied the novel's title. The novel, which has been classified as both science fiction and romance, examines the themes of love, loss, and free will. In particular, the novel uses time travel to explore miscommunication and distance in relationships, while also investigating deeper existential questions.

The Torrents of Spring is a novella written by Ernest Hemingway, published in 1926. Subtitled "A Romantic Novel in Honor of the Passing of a Great Race", Hemingway used the work as a spoof of the world of writers. It is Hemingway's first long work and was written as a parody of Sherwood Anderson's Dark Laughter.

The Watsons Go to Birmingham – 1963 is a historical-fiction novel by Christopher Paul Curtis. First published in 1995, it was reprinted in 1997. It tells the story of a loving African-American family living in the town of Flint, Michigan, in 1963. When the oldest son (Byron) begins to get into a bit of trouble, the parents decide he should spend the summer and possibly the next school year with Grandma Sands in Birmingham, Alabama. The entire family travels there together by car, and during their visit, tragic events take place. The book was adapted for Hallmark Channel in 2013.

What Looks Like Crazy on an Ordinary Day is the 1997 debut novel by Pearl Cleage. It was published by Avon on December 1, 1997 and was selected for the Oprah Winfrey Book Club in 1998 and was a New York Times Best Seller for nine straight weeks.What Looks Like Crazy on an Ordinary Day marks Pearl Cleage's first published novel and it is followed by the 2001 novel I Wish I Had a Red Dress. The novel depicts the life of a young African-American woman named Ava Johnson in the following months after being diagnosed with HIV; in addition to the realities of living with a retrovirus, Cleage's work addresses issues involving race, sexuality, gender, class, and ability in American society.