
AWStats is an open source Web analytics reporting tool, suitable for analyzing data from Internet services such as web, streaming media, mail, and FTP servers. AWStats parses and analyzes server log files, producing HTML reports. Data is visually presented within reports by tables and bar graphs. Static reports can be created through a command line interface, and on-demand reporting is supported through a Web browser CGI program.

BackupPC is a free disk-to-disk backup software suite with a web-based frontend. The cross-platform server will run on any Linux, Solaris, or UNIX-based server. No client is necessary, as the server is itself a client for several protocols that are handled by other services native to the client OS. In 2007, BackupPC was mentioned as one of the three most well known open-source backup software, even though it is one of the tools that are "so amazing, but unfortunately, if no one ever talks about them, many folks never hear of them".

Big Medium was a browser-based web content management system (CMS) written in the Perl programming language and developed by Global Moxie, the Paris-based company of independent developer Josh Clark.

BioPerl is a collection of Perl modules that facilitate the development of Perl scripts for bioinformatics applications. It has played an integral role in the Human Genome Project.

Bricolage is a content management system (CMS) written in the Perl programming language.

Catalyst is an open source web application framework written in Perl, that closely follows the model–view–controller (MVC) architecture, and supports a number of experimental web patterns. It is written using Moose, a modern object system for Perl. Its design is heavily inspired by such frameworks as Ruby on Rails, Maypole, and Spring.

DuckDuckGo is an internet search engine that emphasizes protecting searchers' privacy and avoiding the filter bubble of personalized search results. DuckDuckGo distinguishes itself from other search engines by not profiling its users and by showing all users the same search results for a given search term.

The Fink project is an effort to port and package open-source Unix programs to macOS. Fink uses dpkg and APT, as well as its own frontend program, fink.

Frozen Bubble is a free software clone of Puzzle Bobble for a variety of home and mobile systems.

Logitech Media Server is a streaming audio server supported by Logitech, developed in particular to support their Squeezebox range of digital audio receivers.

Movable Type is a weblog publishing system developed by the company Six Apart. It was publicly announced on September 3, 2001; version 1.0 was publicly released on October 8, 2001. The current version is 7.0.

OTRS is a service management suite. The suite contains an agent portal, admin dashboard and customer portal. In the agent portal, teams process tickets and requests from customers. There are various ways in which this information, as well as customer and related data can be viewed. As the name implies, the admin dashboard allows system administrators to manage the system: Options are many, but include roles and groups, process automation, channel integration, and CMDB/database options. The third component, the customer portal, is much like a customizable webpage where information can be shared with customers and requests can be tracked on the customer side.

Padre is a multi-language software development platform comprising an IDE and a plug-in system to extend it. It is written primarily in Perl and is used to develop applications in this language.

Plack is a Perl web application programming framework inspired by Rack for Ruby and WSGI for Python, and it is the project behind the PSGI specification used by other frameworks such as Catalyst and Dancer. Plack allows for testing of Perl web applications without a live web server.

POPFile is a free, open-source, cross-platform mail filter originally written in Perl by John Graham-Cumming and maintained by a team of volunteers. It uses a naive Bayes classifier to filter mail. This allows the filter to "learn" and classify mail according to the user's preferences. Typically it is used to filter spam mail. It can also be used to sort mail into other user defined "buckets" or categories - for example, the user may define a bucket into which work email is sorted.

Proxmox Virtual Environment is an open-source server virtualization management platform. It is a Debian-based Linux distribution with a modified Ubuntu LTS kernel and allows deployment and management of virtual machines and containers. Proxmox VE includes a web console and command-line tools, and provides a REST API for third-party tools. Two types of virtualization are supported: container-based with LXC, and full virtualization with KVM. It comes with a bare-metal installer and includes a web-based management interface.

Raspcontrol is a web-based system monitoring tool designed primarily for the Raspberry Pi but is compatible with Unix like systems too. The source code is open-source.

Request Tracker, commonly abbreviated to RT, is a ticket-tracking system written in Perl used to coordinate tasks and manage requests among a community of users. RT's first release in 1996 was written by Jesse Vincent, who later formed Best Practical Solutions LLC to distribute, develop, and support the package. RT is open source (FOSS) and distributed under the GNU General Public License.

Apache SpamAssassin is a computer program used for e-mail spam filtering. It uses a variety of spam-detection techniques, including DNS and fuzzy checksum techniques, Bayesian filtering, external programs, blacklists and online databases. It is released under the Apache License 2.0 and is a part of the Apache Foundation since 2004.

SQL-Ledger is an ERP and double entry accounting system. Accounting data is stored in an SQL Database Server and a standard web browser can be used as its user interface. The system uses the Perl language with a database interface module for processing and PostgreSQL for data storage which is the preferred platform. The download version also includes schemas for IBM's DB2 database server as well as Oracle.

VERTCON is a computer program that computes the modeled difference in orthometric height between the North American Vertical Datum of 1988 and the National Geodetic Vertical Datum of 1929 for a location in the contiguous United States. The parameters required are the latitude and longitude of the location.

W3Perl is a free software logfile analyser, which can parse Web/FTP/Mail/CUPS/DHCP/SSH and Squid logfiles. Most major web logfile formats are supported, as well as split/compressed files. "Page tagging" and counter are also supported if you do not have logfiles access. The output is spread over HTML pages, with graphics and a sortable table. Stats can be run from a single command line or from a web browser.

WebGUI is an open-source content management system written in Perl and released under the GNU General Public License.

Webmin is a web-based system configuration tool for Unix-like systems, although recent versions can also be installed and run on Microsoft Windows. Webmin allows the user to configure operating system internals, such as users, disk quotas, services or configuration files, as well as modify and control open-source apps, such as the Apache HTTP Server, PHP or MySQL.

The WikiWikiWeb is the first wiki, or user-editable website. It was launched on 25 March 1995 by its inventor, programmer Ward Cunningham, to accompany the Portland Pattern Repository website discussing software design patterns. The name WikiWikiWeb originally also applied to the wiki software that operated the website, written in the Perl programming language and later renamed to "WikiBase". The site is frequently referred to by its users as simply "Wiki", and a convention established among users of the early network of wiki sites that followed was that using the word with a capitalized W referred exclusively to the original site.

Zaz is a free software (GPLv3) arcade action puzzle computer game, similar to Zuma.