Cajamarca, also known by the Cajamarca Quechua name, Kashamarka, is the capital and largest city of the Cajamarca Region as well as an important cultural and commercial center in the northern Andes. It is located in the northern highlands of Peru at approximately 2,750 m (8,900 ft) above sea level in the valley of the Mashcon river. Cajamarca had an estimated population of about 226,031 inhabitants in 2015, making it the 13th largest city in Peru.

Cusco, often spelled Cuzco [ˈkusko], is a city in southeastern Peru near the Urubamba Valley of the Andes mountain range. It is the capital of the Cusco Region and of the Cusco Province. The city is the seventh most populous in Peru, and, in 2017, it had a population of 428,450. Its elevation is around 3,400 m (11,200 ft).

The Inca Empire, also known as the Incan Empire and the Inka Empire, was the largest empire in pre-Columbian America. The administrative, political and military center of the empire was in the city of Cusco. The Inca civilization arose from the Peruvian highlands sometime in the early 13th century. Its last stronghold was conquered by the Spanish in 1572.

Inca rule in Chile was brief; it lasted from the 1470s to the 1530s when the Inca Empire was absorbed by Spain. The main settlements of the Inca Empire in Chile lay along the Aconcagua, Mapocho and Maipo rivers. Quillota in Aconcagua Valley was likely the Incas' foremost settlement. The bulk of the people conquered by the Incas in Central Chile were Diaguitas and part of the Promaucae.

Intihuatana at the archaeological site of Machu Picchu is a notable ritual stone associated with the astronomic clock or calendar of the Inca in South America. Machu Picchu was thought to have been built c. 1450 by the Sapa Inca Pachacuti as a country estate, although it is equally likely that the Inca discovered much older ruins and opted to build this majestic estate on older foundations.. In the late 16th century, the Viceroy Francisco de Toledo and the clergy destroyed those Intihuatana which they could find. They did so as they believed that the Incas' religion was a blasphemy and the religious significance of the Intihuatana could be a political liability. The Intihuatana of Machu Picchu was found intact by Bingham in 1911, indicating that the Spanish conquerors had not found it.

Machu Picchu is a 15th-century Inca citadel, located in the Eastern Cordillera of southern Peru, on a 2,430-metre (7,970 ft) mountain ridge. It is located in the Machupicchu District within Urubamba Province above the Sacred Valley, which is 80 kilometres (50 mi) northwest of Cuzco. The Urubamba River flows past it, cutting through the Cordillera and creating a canyon with a tropical mountain climate.

The Neo-Inca State, also known as the Neo-Inca state of Vilcabamba, was the Inca state established in 1537 at Vilcabamba by Manco Inca Yupanqui. It is considered a rump state of the Inca Empire (1438–1533), which collapsed after the Spanish conquest in the mid-1500s. The Neo-Inca State lasted until 1572, when the last Inca stronghold was conquered, and the last ruler, Túpac Amaru, was captured and executed, thus ending the political authority of the Inca state.
The Sapa Inca, Sapan Inka or Sapa Inka, also known as Apu ("divinity"), Inka Qhapaq, or simply Sapa, was the ruler of the Kingdom of Cuzco and later, the Emperor of the Inca Empire (Tawantinsuyu) and the Neo-Inca State. While the origins of the position are mythical and originate from the legendary foundation of the city of Cusco, it seems to have come into being historically around 1100 CE. Although the Inca believed the Sapa to be the son of Inti and often referred to him as Intip Churin or ‘Son of the Sun,’ the position eventually became hereditary, with son succeeding father. The principal wife of the Inca was known as the Coya or Qoya. The Sapa Inca was at the top of the social hierarchy, and played a dominant role in the political and spiritual realm.

Vilcabamba, Willkapampa is often called the Lost City of the Incas. Vilcabamba means "sacred plain" in Quechua. The modern name for the Inca ruins of Vilcabamba is Espiritu Pampa. Vilcabamba is located in Echarate District of La Convención Province in the Cuzco Region of Peru.

Vitcos was a residence of Inca nobles and a ceremonial center of the Neo-Inca State (1537-1572). The archaeological site of ancient Vitcos, called Rosaspata, is in the Vilcabamba District of La Convención Province, Cusco Region in Peru. The ruins are on a ridge overlooking the junction of two small rivers and the village of Pucyura. The Incas had occupied Vilcabamba, the region in which Vitcos is located, about 1450 CE, establishing major centers at Machu Picchu, Choquequirao, Vitcos, and Vilcabamba. Vitcos was often the residence of the rulers of the Neo-Inca state until the Spanish conquest of this last stronghold of the Incas in 1572.