WDomingo de la Anunciación (1510–1591), born Juan de Ecija, was a Spanish Dominican missionary in New Spain.
WFrancisco de Ayeta was a Spanish Franciscan missionary of the 17th century, in New Spain and Mexico.
WJohann Jakob Baegert was a Jesuit missionary at San Luis Gonzaga in Baja California Sur, Mexico. He is noted for his detailed and acerbic account of the peninsula, the culture of its native inhabitants, and the history of its Spanish exploration and missionization.
WPeter of Saint Joseph de Betancur y Gonzáles, O.F.B. (Spanish: Pedro de San José de Betancur y Gonzáles, March 21, 1626 – April 25, 1667, called Hermano Pedro de San José Betancurt or more simply Peter de Betancurt, Hermano Pedro, Santo Hermano Pedro, or San Pedro de Vilaflor, was a Spanish saint and missionary in Guatemala. Known as the "St. Francis of Assisi of the Americas", he is the first saint native to the Canary Islands, is also considered the first saint of Guatemala and Central America for having done his missionary work in those American lands. He was the founder of Order of Our Lady of Bethlehem.
WHoracio Carochi (1586–1666) was a Jesuit priest and grammarian who was born in Florence and died in Mexico. He is known for his grammar of the Classical Nahuatl language.
WLorenzo José Carranco was a Jesuit missionary.
WJuan de Córdova was a Spanish Dominican friar, known for his studies of the Zapotec languages. It is not certain whether Córdova was his family name, or whether he assumed it from his native city after he became a Dominican.
WJoan Crespí or Juan Crespí was a Franciscan missionary and explorer of Las Californias.
WDiego Durán was a Dominican friar best known for his authorship of one of the earliest Western books on the history and culture of the Aztecs, The History of the Indies of New Spain, a book that was much criticised in his lifetime for helping the "heathen" maintain their culture.
WJuan de Esteyneffer was a Moravian German lay Jesuit missionary sent to the New World. He is known for his 1711 work Florilegio Medicinal, which compiled a combination of New World traditional medicine, European materia medica, and 18th-century European medical diagnosis.
WFrancisco Hermenegildo Tomás Garcés, O.F.M., was a Spanish Franciscan friar who served as a missionary and explorer in the colonial Viceroyalty of New Spain. He explored much of the southwestern region of North America, including present day Sonora and Baja California in Mexico, and the U.S. states of Arizona and California. He was killed along with his companion friars during an uprising by the Native American population, and they have been declared martyrs for the faith by the Catholic Church. The cause for his canonization was opened by the Church.
WLuis Jayme O.F.M., born Melcior Jaume Vallespir, was a Spanish-born Roman Catholic priest of the Franciscan Order. Born at the farm Son Baró in the village of Sant Joan, Majorca, his earliest schooling was acquired from the local parish priest. At the age of fifteen Melchor was enrolled at the convent school of San Bernardino, where Fray Junípero Serra had studied some years earlier.
WEusebio Francisco Kino, often referred to as Father Kino, was an Italian Jesuit, missionary, geographer, explorer, cartographer and astronomer born in the Territory of the Bishopric of Trent, then part of the Holy Roman Empire. For the last 24 years of his life he worked in the region then known as the Pimería Alta, modern-day Sonora in Mexico and southern Arizona in the United States. He explored the region and worked with the indigenous Native American population, including primarily the Tohono O'Odham, Sobaipuri and other Upper Piman groups. He proved that the Baja California Peninsula is not an island by leading an overland expedition there. By the time of his death he had established 24 missions and visitas.
WFerdinand Konščak was a Croatian Jesuit missionary, explorer and cartographer.
WFermín de Francisco Lasuén de Arasqueta was a Spanish Franciscan missionary to Alta California president of the Franciscan missions there, and founder of nine of the twenty-one Spanish missions in California.
WMartín de Murúa, O. de M., was a Basque Mercedarian friar and chronicler of the Spanish conquest of the Americas. He is primarily known for his work Historia general del Piru, which is considered the earliest illustrated history of Peru.
WAntonio de San Buenaventura y Olivares or simply Fray Antonio de Olivares was a Spanish Franciscan who officiated at the first Catholic Mass celebrated in Texas, and he was known for contributing to the founding of San Antonio and to the prior exploration of the area.
WIvan Ratkaj, also Ivan Rattkay, was a Jesuit missionary, explorer and cartographer. He wrote the first detailed description of the Tarahumara, a Native Mexican people.
WBernardino de Sahagún was a Franciscan friar, missionary priest and pioneering ethnographer who participated in the Catholic evangelization of colonial New Spain. Born in Sahagún, Spain, in 1499, he journeyed to New Spain in 1529. He learned Nahuatl and spent more than 50 years in the study of Aztec beliefs, culture and history. Though he was primarily devoted to his missionary task, his extraordinary work documenting indigenous worldview and culture has earned him the title as “the first anthropologist." He also contributed to the description of the Aztec language Nahuatl. He translated the Psalms, the Gospels, and a catechism into Nahuatl.
WJuan María de Salvatierra, S.J., was a Catholic missionary to the Americas.
WPhilipp Segesser was a German-speaking Swiss Jesuit missionary who spent much of his career in Sonora, Mexico.
WJuan Solano, O.P., was a Spanish Dominican missionary and the second Catholic bishop of the Diocese of Cuzco, Peru (1544–1562).
WVicente de Valverde y Alvarez de Toledo, O.P., or Vincent de Valle Viridi was a Spanish Dominican friar who was involved in the Conquest of the Americas, later becoming the Bishop of Cuzco. He became the first resident bishop in South America. He was born in Oropesa, Spain, about 1495 and most sources claim he died on Puná Island, now part of Ecuador, in 1541, at the hands of the indigenous peoples.