
The 2006 Borujerd earthquake occurred in the early morning of 31 March in the South of Borujerd with destruction in Borujerd, Silakhor and Dorood areas of the Loristan Province in western Iran. The centre of the earthquake was in Darb-e Astaneh village south of the Borujerd City. The earthquake measured 6.1 on the moment magnitude scale.

On September 1, 2006, Iran Air Tours Tu-154 aircraft traveling from Bandar Abbas with 11 crew and 137 passengers on board burst into flames upon landing in Mashhad, Iran at 13:45 local time killing 28 of those on board.

The Iran newspaper cockroach cartoon controversy occurred in response to a cartoon drawn by the cartoonist Mana Neyestani and published in the Iranian holiday-magazine Iran-e-jomee on 12 May 2006.

On May 8, 2006, Iranian President Mahmoud Ahmadinejad sent a missive directly to then United States President George W. Bush that proposed "new ways" to end the dispute over the Islamic Republic's development of nuclear power.

One Million Signatures for the Repeal of Discriminatory Laws, also known as Change for Equality, is a campaign by women in Iran to collect one million signatures in support of changing discriminatory laws against women in their country.

United Nations Security Council Resolution 1696, adopted on July 31, 2006, after expressing concern at the intentions of the nuclear programme of Iran, the Council demanded that Iran halt its uranium enrichment programme.

United Nations Security Council Resolution 1737 was unanimously passed by the United Nations Security Council on 23 December 2006.