
The 1st Filipino Infantry Regiment was a segregated United States Army infantry regiment made up of Filipino Americans from the continental United States and a few veterans of the Battle of the Philippines that saw combat during World War II. It was formed and activated at Camp San Luis Obispo, California, under the auspices of the California National Guard. Originally created as a battalion, it was declared a regiment on 13 July 1942. Deployed initially to New Guinea in 1944, it became a source of manpower for special forces and units that would serve in occupied territories. In 1945, it deployed to the Philippines, where it first saw combat as a unit. After major combat operations, it remained in the Philippines until it returned to California and was deactivated in 1946 at Camp Stoneman.

The 26th Cavalry Regiment was part of U.S. Army Forces Far East's Philippine Department, during World War II. The 26th engaged in the last cavalry charge in the history of the U.S. cavalry. The American Battle Monuments Commission list 301 dead who were members of this regiment interred at Manila American Cemetery and Memorial.

The 57th Infantry Regiment was a unit in the Philippine Scouts. During their combat in Bataan members received 1 Medal of Honor, 21 Distinguished Service Crosses and 68 Silver Stars.

Peter Aquino Aduja was the first Filipino American elected to public office in the United States. He was elected as a representative in the Hawaii Legislature in 1954.

Jesse Nathanael "Nathan" Aliganga was a United States Marine Corps security guard who was killed in the 1998 U.S. embassy bombings in Nairobi, Kenya. He was the only U.S. Marine killed in the bombings.

Brian Joseph Bulatao is an American businessman and government official. In 2017 he was named as Chief Operating Officer of the Central Intelligence Agency by then-agency director Mike Pompeo. In June 2018, Bulatao was nominated to be Under Secretary of State for Management by President Donald Trump. On May 16, 2019, Bulatao was confirmed by the United States Senate; he was sworn in the next day.

Jose Cabalfin Calugas was a member of the Philippine Scouts during World War II. He received the Medal of Honor for actions during the Battle of Bataan.

Rudolph B. Davila, born in El Paso, Texas, was a United States Army officer, of Spanish-Filipino descent, who received the Medal of Honor for his actions in Italy during World War II. He was the only person of Filipino ancestry to receive the medal for his heroic actions in the European theatre. He was initially awarded the Distinguished Service Cross. However, in 1998, after an extensive review, his medal was upgraded to the Medal of Honor.

Oscar Hilman, is a Filipino American, Brigadier General or BG, and US Army Commander of the Heavy Armor Brigade at Joint Base Balad and Logistics Area Anaconda aka Camp Anaconda, formerly known as Al-Bakr Air Base in Iraq. In Iraq, he was tasked to prevent troop and allied forces withdrawals from Camp Anaconda, one of the largest US military bases in Iraq. In a series of town hall meetings, he spoke to the Filipino workers—often in Tagalog—and persuaded them to stay put by assuring them of their safety in camp. To show good faith, he gave the contractors base privileges, a move that was approved by the US chain of command.

Eleanor Concepcion "Connie" Mariano, is a Filipina American physician and retired flag officer in the United States Navy. She is the first Filipino American and graduate of the Uniformed Services University of Medicine to reach the rank of Rear Admiral in the U.S. Navy as well as the second woman to become Physician to the President, a position that placed her as director of the White House Medical Unit.

Marine Corps Yumi is a manga about life in the United States Marine Corps, written by former member Anastasia Moreno and illustrated by Takeshi Nogami. It is published in Japan by Kodansha, and as a webcomic by Sai-zen-sen (最前線) in both Japanese and English.

Gina Ortiz Jones is an American intelligence officer and politician. She was the 2018 Democratic nominee for Texas's 23rd congressional district, and her candidacy drew national attention for the potential “firsts” she would represent as a gay woman of color and military veteran running for office in Texas, but she narrowly lost to the incumbent Republican Will Hurd. In May 2019, she launched a second campaign for the office. In the November 2020 general election, Republican nominee Tony Gonzales defeated Jones by four percentage points.

The Philippine Scouts was a military organization of the United States Army from 1901 until after the end of World War II. These troops were generally Filipinos and Filipino-Americans assigned to the United States Army Philippine Department, under the command of American commissioned officers. Philippine Scout units were given the suffix "(PS)", to distinguish them from other U.S. Army units.

Eldon Regua is a retired major general in the United States Army Reserve, who last served as Deputy Commanding General/Chief of Staff (Wartime) for 8th United States Army headquartered in Yongsan, Korea, having just completed an assignment as Commanding General, 75th Division in Houston, Texas in July 2011. As of 2010, he was the senior most active, or reserve, non-retired flag or general officer of Filipino American ethnicity. He is also half Mexican American ethnicity.

USS Rizal (DD–174) was a Wickes-class destroyer in the United States Navy following World War I. She was named for José Rizal, a Filipino patriot.

Rudy Robles born Pastor Lluviosa Robles was a Filipino film and television actor. He was one of the first Filipino actors to appear in Hollywood movies.

Lieutenant General Edward Soriano is an American retired military officer. He is the highest-ranking Filipino American officer to have served in the United States military, and the first promoted to a general officer. Born in the Philippines, Soriano moved with his family to the United States and graduated from Salinas High School before being commissioned as an officer through Army Reserve Officers' Training Corps at San Jose State University.

Ramon Simpas Subejano (1905–1988), a Filipino American originally from the Philippines, was a decorated United States World War II veteran.

Benigno G. Tabora was a Filipino American veteran of both World War II and the Korean War. Tabora was one of the last of an increasingly dwindling group of veterans who survived the Bataan Death March in May 1942 after the Japanese captured the Philippines during World War II. He spent eight months as a prisoner of war in a Japanese internment camp. Tabora served in the military intelligence during his 31 years in the Army.

Antonio Mario Taguba is a retired major general in the United States Army. He was the second American citizen of Philippine birth to be promoted to general officer rank in the United States Army.

Telesforo de la Crux Trinidad was a Filipino fireman 2nd class in the United States Navy who received the Medal of Honor for actions, in Mexican waters near La Paz, on board the USS San Diego on 21 January 1915. He was the second service member, and first and so far the only Sailor of Asian descent to receive the award in peacetime. Trinidad served during both World Wars before retiring to the Philippines and living on his pension.

Rear Admiral Eleanor V. Valentin was the first female flag officer to serve as director of the United States Navy Medical Service Corps. She assumed command of Navy Medicine Support Command and assumed duties as the 16th director of the Medical Service Corps on 1 October 2009.