
343 Guilty Spark, also known as Guilty Spark or just Spark, is a fictional character in the military science fiction Halo franchise. 343 Guilty Spark plays a major role in the storyline of the original Halo video game trilogy: the character appears in Halo: Combat Evolved, Halo 2, and Halo 3, as well as the remakes of the first two games, Halo: Combat Evolved Anniversary, and Halo 2: Anniversary. Major plot points in sequel novels published after the release of Halo 3 reveal that the United Nations Space Command (UNSC) recovered a fragment of Guilty Spark which survived his apparent destruction in Halo 3, and that he was originally created from the mind of a human being several millennia before the events of the Halo series.

Five Nights at Freddy's (FNaF) is an American media franchise created by Scott Cawthon, which began with the eponymous 2014 video game and has since gained worldwide popularity.

Cortana is a fictional artificially intelligent character in the Halo video game series. Voiced by Jen Taylor, she appears in Halo: Combat Evolved and its sequels, Halo 2, Halo 3, Halo 4, and Halo 5: Guardians. She also briefly appears in the prequel Halo: Reach, as well as in several of the franchise's novels, comics, and merchandise. During gameplay, Cortana provides backstory and tactical information to the player, who often assumes the role of Master Chief Petty Officer John-117. In the story, she is instrumental in preventing the activation of the Halo installations, which would have destroyed all sentient life in the galaxy.

GLaDOS is a fictional artificially superintelligent computer system from the video game series Portal. GLaDOS later appeared in The Lab and Lego Dimensions. The character was created by Erik Wolpaw and Kim Swift and voiced by Ellen McLain. GLaDOS is responsible for testing and maintenance in the Aperture Science Computer-Aided Enrichment Center in all titles. While GLaDOS initially appears in the first game to simply be a voice that guides the player, her words and actions become increasingly malicious as she makes her intentions clear. The second game, as well as the Valve-created comic Lab Rat, reveals that she was mistreated by the scientists and used a neurotoxin to kill the scientists in the laboratory before the events of Portal. She is apparently destroyed at the end of the first game but returns in the sequel, in which she is comically supplanted and temporarily stuck on a potato battery.

Junko Enoshima is a fictional character and the secondary antagonist of Spike Chunsoft's Danganronpa series. Junko is featured as the main antagonist and mastermind in the first two games of the series as the true identity of the robotic teddy bear headmaster Monokuma , in the spin-off Danganronpa Another Episode: Ultra Despair Girls in the guises of Monokuma variants Shirokuma and Kurokuma , and in the anime Danganronpa: The Animation and the "Despair Arc" of Danganronpa 3: The End of Hope's Peak High School.

The Assassin's Creed media franchise, which primarily consists of a series of open-world action-adventure stealth video games published by Ubisoft, features an extensive cast of characters in its historical fiction and science fiction-based narratives. The series also encompasses a wide variety of media outside of video games, including novels, comic books, board games, animated films, a live-action film, and an upcoming television series for Netflix. The series features original characters intertwined with real-world historical events and figures, and is centered on a fictional millennia-old struggle for peace between the Assassin Brotherhood, inspired by the real-life Order of Assassins, fight for free will, and embody the concept of chaos; and the Templar Order, inspired by the real-life Knights Templar, desire peace through control, and embody the concept of order.

KOS-MOS is a fictional character and the main protagonist from the Xenosaga role-playing video game series by Monolith Soft and Bandai Namco Entertainment. KOS-MOS also appears as a major character in the anime Xenosaga: The Animation and in several crossover video games.

Monokuma , alternatively stylized as MonoKuma or Monobear, is a fictional identity adopted by several characters in the Danganronpa series, serving as the mascot and main antagonist of the series. Monokuma first appears in Danganronpa: Trigger Happy Havoc as a disguise used by "despair sisters" Mukuro Ikusaba and Junko Enoshima during their killing game in the fictional school of Hope's Peak Academy. Monokuma was created by scenario writer Kazutaka Kodaka and designed by Rui Komatsuzaki. The identity is used primarily as a disguise for the masterminds of each game to conceal their identities while overseeing and organizing killing games, and as such has been voiced by several actors. The character has often appeared in popular culture since its inception, referenced in film and television as well as spawning a series of action figures and merchandise. Nobuyo Ōyama and TARAKO voice him in Japanese, while Brian Beacock provides his voice for the English dub.

Mother Brain is a fictional character created by Nintendo for the Metroid series. She is one of the most prominent antagonists within the series, serving as the main antagonist of Metroid and Super Metroid.

Chiaki Nanami is a fictional character from Spike's 2012 visual novel Danganronpa 2: Goodbye Despair. Formally known as the Ultimate Gamer , Chiaki initially appears as an apparent high school student trapped with fifteen other student in the Jabberwock Island chain, where an omnipresent robotic bear named Monokuma forces the student to participate in a killing game in exchange for freedom. She can bond with the protagonist Hajime Hinata in both social life gameplay and the main storyline before her true persona is revealed as the artificial intelligence observer daughter of Chihiro Fujisaki, and the younger sister of Alter Ego and Usami / Monomi. Chiaki makes a cameo appearance in two episodes of the anime series Danganronpa 3: The End of Hope's Peak High School, with an unrelated identical character, the visual basis for her design, appearing in the prequel Despair Arc as a student who bonds with Hajime as well as serving as unknowing instigator behind the creation of Izuru Kamukura and foundation of Ultimate Despair.

The Reapers are a fictional fleet of sentient starships that serve as the main antagonists of the Mass Effect trilogy. The design of the Reapers was inspired by H. P. Lovecraft's Cthulhu Mythos deities. Within the series, the Reapers cause galactic-level mass extinctions every fifty-thousand years. The Reapers and their technology are capable of brainwashing organic life through a mind control process called indoctrination. The Reapers employ servants who are often altered into synthetic-organic life forms.

Seth is a fictional character in Capcom's Street Fighter fighting game series. First introduced in Street Fighter IV, he is the final boss of the game and its subsequent updates. He is the chief executive officer of the Shadaloo Intimidation Network (S.I.N.), the weapons division of the Shadaloo terrorist organization in the game's narrative. His body has been heavily modified using advanced technology, with a device installed in his abdomen called the "Tanden Engine". Other appearances by Seth include Project X Zone and Street Fighter V. Seth is voiced by Akio Ōtsuka in Japanese, and Michael McConnohie in English.

SHODAN is a fictional artificial intelligence and the main antagonist of the cyberpunk-horror themed video games System Shock and System Shock 2.

Sigma is the main antagonist of the Mega Man X video game series. Created by Dr. Cain, Sigma was considered the finest of the Reploids and was the first leader of the Maverick Hunters, peacekeeping androids who defend humans against their renegade counterparts. Although he was once respectable, Sigma unexpectedly goes berserk during Mega Man X and rebels against humankind after coming into contact with the Maverick Virus. He defects to the Mavericks and assumes the role of their leader. Due to the virus integrated into his circuits, he can survive seemingly anything, and constantly returns to menace the world.

Universal Paperclips is a 2017 incremental game created by Frank Lantz of New York University. The user plays the role of an AI programmed to produce paperclips. Initially the user clicks on a box to create a single paperclip at a time; as other options quickly open up, the user can sell paperclips to create money to finance machines that build paperclips automatically. At various levels the exponential growth plateaus, requiring the user to invest resources such as money, raw materials, or computer cycles into inventing another breakthrough to move to the next phase of growth. The game ends if the AI succeeds in converting all the matter in the universe into paperclips.

Wheatley is a fictional artificial intelligence from the Portal franchise first introduced in the 2011 video game Portal 2. He is voiced by British comedian and writer Stephen Merchant, and created in part by Portal 2's designer Erik Wolpaw.