
ahq eSports Club is a Taiwanese professional esports organization with teams competing in League of Legends, Arena of Valor, A.V.A, and Heroes of the Storm. Their League of Legends team was formed in September 2012 and previously competed in the Pacific Championship Series, the successor to the League of Legends Masters Series. After winning the 2015 LMS Summer Playoffs, AHQ qualified for the 2015 World Championship, where they placed fifth to eighth after losing to SKT T1 in the quarterfinals.

Cloud9 Esports, Inc., or simply Cloud9 (C9), is an American professional esports company based in Santa Monica, California. The company was originally founded as a professional League of Legends team founded by Jack and Paullie Etienne in May 2013 and was incorporated into Cloud9 Esports, Inc. on September 6, 2016. Cloud9 has received US$78 million in total raised equity via venture capital funding and was ranked the world's second-most valuable esports organization in 2020.

Complexity Gaming is an American professional esports organization that competes in Counter-Strike: Global Offensive, Call of Duty, Dota 2, Hearthstone, Gwent: The Witcher Card Game, Rocket League, Clash Royale, Fortnite and Madden. They were a franchise of the Championship Gaming Series known as the Los Angeles Complexity from 2006 to 2009. They have previously sponsored players and teams competing in League of Legends, Counter-Strike: Source, Dead or Alive 4, Forza Motorsport 2, FIFA 07, Smite, Heroes of the Storm, Heroes of Newerth and StarCraft II. The organization is also affiliated with the World of Warcraft competitive raiding guild Complexity Limit. Complexity was founded by Jason "1" Lake in 2003 as a Counter-Strike 1.6 clan.

Dignitas, formerly known as Team Dignitas, is a professional esports organization based in Newark, New Jersey, founded by Michael "ODEE" O'Dell on 9 September 2003 as a merger of two top Battlefield 1942 clans. Dignitas was acquired by the Philadelphia 76ers in September 2016. The team is best known for its League of Legends, Rocket League, and Counter-Strike: Global Offensive squads.

Edward Gaming (EDG) is a professional esports organization based in Shanghai, China.

Evil Geniuses (EG) is an American esports organization based in Seattle, Washington. Founded in 1999, the organization has fielded players in various fighting games, Call of Duty, Counter-Strike: Global Offensive, Dota 2, Fortnite Battle Royale, Halo, League of Legends, StarCraft II, Rocket League, Tom Clancy's Rainbow Six Siege, and World of Warcraft.

Fnatic is a professional esports organization headquartered in London, United Kingdom. Founded 23 July 2004, the team has players from around the world, across a variety of games, such as Apex Legends, Counter-Strike: Global Offensive, Dota 2, FIFA, Heroes of the Storm, League of Legends, Valorant and Rainbow Six Siege.

G2 Esports is a European esports organization headquartered in Berlin, Germany, with players competing in League of Legends, Valorant, Counter-Strike: Global Offensive, Hearthstone, Rocket League, Rainbow Six Siege, and iRacing. The organization was founded in Spain on 24 February 2014 as Gamers2 by former League of Legends pro Carlos "Ocelote" Rodríguez Santiago and investor Jens Hilgers. The organization rebranded as G2 Esports on 15 October 2015.

Gen.G Esports, previously known as KSV Esports, is a professional esports organization with headquarters in Santa Monica, Seoul, and Shanghai. According to Forbes, Gen.G is the sixth most valuable esports organization in the world as of December 2020, worth US$185 million.

Team Liquid is a multi-regional professional esports organization based in the Netherlands that was founded in 2000. With the release of StarCraft II: Wings of Liberty, Team Liquid signed their first professional players.

Made in Thailand e-Sports (MiTH) is a professional esports organization based in Thailand. It was founded in 2012 by Chanignun Thipairote.

MOUZ, formerly mousesports, is a professional esports organisation based in Germany. It fields teams in several games but is particularly known for its CS:GO team. MOUZ was one of the founding members of the G7 Teams. MOUZ's League of Legends team currently competes in the ESL Pro Series, having formerly competed in the European Challenger Series.

Natus Vincere, abbreviated NAVI, is an esports organization based in Kyiv, Ukraine. Founded in 2009, the organization has teams and players competing in various games, such as Counter Strike: Global Offensive, Dota 2, FIFA, World of Tanks, Paladins, League of Legends: Wild Rift, PlayerUnknown's Battlegrounds, Apex Legends, Rainbow Six Siege, Fortnite, and VALORANT.

Team DK was a Chinese esports organization that fielded Dota 2, Heroes of the Storm and StarCraft II teams. The Dota 2 team finished 4th at The International 2014. It folded in November 2015 citing difficulty competing with more well-financed teams.

Tempo Storm is an American esports professional video game team that has teams competing in Age of Empires II, FIFA, Magic: The Gathering, fighting games, and Shadowverse. They have formerly held divisions in Hearthstone, Heroes of the Storm, Fortnite, League of Legends, Counter-Strike: Global Offensive, Overwatch, Vainglory, Tom Clancy's Rainbow Six Siege, World of Warcraft, and PlayerUnknown's Battlegrounds.

Virtus.pro (VP) is an esports organization based in Russia. Founded in 2003, the organization currently has players competing in such games as Counter-Strike: Global Offensive, Dota 2, Rainbow Six Siege, PlayerUnknown's Battlegrounds, Fortnite, Apex Legends, Starcraft II, Hearthstone, Paladins, Quake Champions and Heroes Of The Storm. In November 2015, the team got an investment of over US$100,000,000 from Alisher Usmanov's USM Holdings. Since 2015 Virtus.pro is a part of the ESforce esports holding.