
The welfare of animals in rodeo has been a topic of discussion for the industry, the public, and the law for decades. Protests were first raised in the 1870s, and, in the middle twentieth century, laws were enacted to curb events using animals. The American Humane Association (AHA) has worked with the rodeo industry to establish rules improving animal welfare in rodeo and the treatment of rodeo animals.

B. F. Brisac was an American business executive and humanitarian known for his work with the San Francisco Society for the Prevention of Cruelty to Animals and other humane organizations in the early 1900s.

Dog fighting in the United States is an activity in which fights between two game dogs are staged as a form of entertainment and gambling. Such activity has existed since the early 19th century in the United States and was gradually prohibited in all states. It continues as an underground activity in both rural and urban locations.
Manatees are large marine mammals that inhabit slow rivers, canals, saltwater bays, estuaries, and coastal areas. They are a migratory species, inhabiting the Florida waters during the winter and moving as far north as Virginia and into the Chesapeake Bay, sometimes seen as far north as Baltimore, Maryland and as far west as Texas in the warmer summer months. Manatees are calm herbivores that spend most of their time eating, sleeping, and traveling. They have a lifespan of about 60 years with no known natural enemies. Some of their deaths are the result of human activity. In the past, manatees were exploited for their meat, fat, and hides.

Mardi Paws is a Mardi Gras procession in Covington, Louisiana dedicated to animal welfare.

Peaceable Kingdom: The Journey Home is a documentary released in 2009 which relates the personal transformation of farmers as they reexamine their relationship to animals. The movie also tells the story of two animal rescues.

The Scarecrow is a 2013 animated short film and advertisement by the American restaurant chain Chipotle Mexican Grill. The film features Fiona Apple singing a cover version of "Pure Imagination", originally performed by Gene Wilder as Willy Wonka in the 1971 film Willy Wonka & the Chocolate Factory.

Star was a mixed-breed female pit bull who was shot by the New York City Police Department in 2012 while she was protecting her homeless owner who was in the midst of a seizure. Star's shooting was captured on video, and went viral, leading to controversies over police handling of companion dogs. Star was born in the Bronx, New York on March 1, 2011.

Tilikum v. Sea World was a legal case heard in the US Federal Court in 2012 concerning the constitutional standing of an orca. It was brought by People for the Ethical Treatment of Animals (PETA) on behalf of Tilikum, an orca kept in the SeaWorld Orlando park, against the SeaWorld corporation.

Veterinary medicine in the United States is the performance of veterinary medicine in the United States, normally performed by licensed professionals, and subject to provisions of statute law which vary by state. Veterinary medicine is normally led by veterinary physicians, termed veterinarians or vets.

The Wild and Free-Roaming Horses and Burros Act of 1971 (WFRHBA), is an Act of Congress, signed into law by President Richard M. Nixon on December 18, 1971. The act covered the management, protection and study of "unbranded and unclaimed horses and burros on public lands in the United States."

The Witness is a 2000 documentary film about animal rights directed by Jenny Stein. It was produced by James LaVeck. LaVeck and Stein's non-profit organization is Tribe of Heart.