
Beng Per Wildlife Sanctuary is a 2,494.08 km2 (962.97 sq mi) large protected area in northern Cambodia that was established in 1993.

Chhep Wildlife Sanctuary is a 1,900.27 km2 (733.70 sq mi) large protected area in northern Preah Vihear Province of Cambodia comprising large tracts of deciduous dipterocarp and evergreen forests, as well as seasonally inundated grasslands and small wetlands. It is contiguous with Preah Roka Wildlife Sanctuary in the southwest.

Keo Seima Wildlife Sanctuary is a 2,926.9 km2 (1,130.1 sq mi) protected area in eastern Cambodia, located in Mondulkiri and Kratié provinces. The area was first established as Seima Biodiversity Conservation Area in 2002, later becoming Seima Protection Forest in 2009, finally becoming Keo Seima Wildlife Sanctuary in 2016. The site is of national, regional, and global importance for a range of biodiversity, with more than 950 species recorded within the protected area. It is also the ancestral and contemporary home of a large number of the Bunong ethnic group.

The Kulen Promtep Wildlife Sanctuary is one of the largest protected area in Cambodia and was set aside to protect the critically endangered, possibly extinct Kouprey.

Lomphat Wildlife Sanctuary is a protected area covering 2,514.68 km2 (970.92 sq mi) in eastern Cambodia that was established in 1993. It is heavily forested and straddles Ratanakiri, Mondulkiri, and Kratie provinces. It is home to a variety of endangered wildlife such as banteng, tiger, gaur, dholes and sun bear, as well as leopards, Eld's deer, sambar deer, muntjacs and wild pigs. In addition, a number of rare birds are present: surveys have confirmed the presence of green peafowl, greater and lesser adjutant storks, sarus cranes, oriental pied hornbills, giant ibises, white-shouldered ibises, milky and wooly-necked storks, and vulture sp., which are increasingly rare in most of South and Southeast Asia.

Peam Krasop Wildlife Sanctuary is a protected area located in southwestern Cambodia, covering 245.91 km2 (94.95 sq mi). It was established in 1993.

Phnom Aural Wildlife Sanctuary is a protected area in central Cambodia, covering 2,544.85 km2 (982.57 sq mi). It was established in 1993. It is named after Phnom Aural, the country's tallest peak at 1,810 m. The Aural mountains are part of the much larger Cardamom Mountains.

Phnom Nam Lyr Wildlife Sanctuary is a large protected area in Mondulkiri Province, Cambodia, established in 1993. It is close to Village I, Bou Sra Commune near the Pech Chreada District bordering Vietnam.

Phnom Prich Wildlife Sanctuary is a 2,218.18 km2 (856.44 sq mi) large protected area in eastern Cambodia that was established in 1993. It is part of maybe the largest protected area complex in southeast Asia. Phnom Prich Wildlife Sanctuary borders Mondulkiri Protected Forest to the north and Keo Seima Wildlife Sanctuary to the south.

Phnom Samkos Wildlife Sanctuary is a wildlife sanctuary in western Cambodia, bordering Thailand. The sanctuary was established in 1994 and covers 3,307.56 km2 (1,277.06 sq mi). It is also designated as an Important Bird Area (IBA).

Phnom Tbeng Natural Heritage Park is a protected area in Cambodia's Northern Plains Landscape. The park was one of five sites considered for world heritage status, along with the Mekong Prek Kampi dolphin sanctuary management protected area, Phnom Nam Lear Rock in Phnom Nam Lyr Wildlife Sanctuary, the Prek Prasab Wildlife Sanctuary, and Southern Cardamom National Park. The protected area contains some of the last remaining evergreen and semi-evergreen forest habitats in northern Cambodia and is of high importance for wildlife conservation and is a key area of the upper watershed of the Steung Saen River, a tributary of the Tonlé Sap.

Preah Roka Wildlife Sanctuary is a 90.361 km2 (34.889 sq mi) protected area in Preah Vihear Province of Cambodia. The stated purpose of its creation in 2016 was to:Ensure protection of wildlife habitat and ecology system and satisfy condition for particular species of flora and fauna and biodiversity Deliver natural products and services for sustainable use Promote local communities and public-based national resource management and biodiversity protection within the area.

The Prey Lang Forest, also known as the Prey Long Forest, is a nature reserve forest in Kampong Thom, Preah Vihear, Kratie and Stung Treng Provinces in Northern Cambodia. The forest covers an estimated 3,600 square kilometres. It is one of Southeast Asia’s last remaining lowland evergreen woodlands. It is the largest remaining lowland evergreen forest on the Indochinese peninsula and approximately 200,000 members of ethnic minorities live in or around the Prey Lang.

Siem Pang Wildlife Sanctuary is a 133,707.73 ha (516.2484 sq mi) wildlife sanctuary located in Santepheap, Thma Keo, and Prek Meas communes, Siem Pang District, Stung Treng Province, created on November 6, 2019 according to Sub-decree no.161 ANKr.BK. This combined the two wildlife sanctuaries: Siem Pang and Western Siem Pang, which were established in 2016.

Snoul Wildlife Sanctuary was located in eastern Cambodia on the border with Vietnam. It is classified as part of an Important Bird Area. The sanctuary, which had been suffering from illegal logging and deforestation for years, was dissolved in February 2018 by a royal decree. Chhay Duong Savuth, director of the Kratie province Environment Department, stated as the main reason the habitat destruction and illegal land settlement. However, a lot of the land was also claimed by private companies that received government approved licences for agriculture use.

Sre Pok Wildlife Sanctuary is a 372,971 ha (1,440.05 sq mi) large wildlife sanctuary in Mondulkiri Province, eastern Cambodia established on May 9, 2016 according to Sub-decree No. 85 ANKr.BK.

Stung Sen is a protected multiple use management area and wildlife sanctuary in the Kampong Thom Province of Cambodia. It is located near the south-eastern tip of the Tonlé Sap, one of three wildlife sanctuaries around the lake, including Boeng Tonlé Chhmar and Prek Toal.