WResearch into the mental disorder of schizophrenia, involves multiple animal models as a tool, including in the preclinical stage of drug development.
WThe African clawed frog is a species of African aquatic frog of the family Pipidae. Its name is derived from the three short claws on each hind foot, which it uses to tear apart its food. The word Xenopus means "strange foot" and laevis means "smooth".
WThe Anopheles gambiae complex consists of at least seven morphologically indistinguishable species of mosquitoes in the genus Anopheles. The complex was recognised in the 1960s and includes the most important vectors of malaria in sub-Saharan Africa, particularly of the most dangerous malaria parasite, Plasmodium falciparum. It is one of the most efficient malaria vectors known. The An. gambiae mosquito additionally transmits Wuchereria bancrofti which causes Lymphatic philariasis, more commonly known as elephantiasis.
WAplysia is a genus of medium-sized to extremely large sea slugs, specifically sea hares, which are one clade of large sea slugs, marine gastropod mollusks.
WThe axolotl, Ambystoma mexicanum, also known as the Mexican walking fish, is a neotenic salamander related to the tiger salamander. Although colloquially known as a "walking fish", the axolotl is not a fish but an amphibian. The species was originally found in several lakes, such as Lake Xochimilco underlying Mexico City. Axolotls are unusual among amphibians in that they reach adulthood without undergoing metamorphosis. Instead of developing lungs and taking to the land, adults remain aquatic and gilled.
WThe little brown bat or little brown myotis is a species of mouse-eared microbat found in North America. It has a small body size and glossy brown fur. It is similar in appearance to several other mouse-eared bats, including the Indiana bat, northern long-eared bat, and Arizona myotis, to which it is closely related. Despite its name, the little brown bat is not closely related to the big brown bat, which belongs to a different genus.
WBombyx mori, the domestic silk moth, is an insect from the moth family Bombycidae. It is the closest relative of Bombyx mandarina, the wild silk moth. The silkworm is the larva or caterpillar of a silk moth. It is an economically important insect, being a primary producer of silk. A silkworm's preferred food are white mulberry leaves, though they may eat other mulberry species and even the osage orange. Domestic silk moths are closely dependent on humans for reproduction, as a result of millennia of selective breeding. Wild silk moths are different from their domestic cousins as they have not been selectively bred; they are thus not as commercially viable in the production of silk.
WThe California sea hare is a species of sea slug in the sea hare family, Aplysiidae. It is found in the Pacific Ocean, off the coast of California in the United States and northwestern Mexico.
WCallosobruchus maculatus is a species of beetles known commonly as the cowpea weevil or cowpea seed beetle. It is a member of the leaf beetle family, Chrysomelidae, and not a true weevil. This common pest of stored legumes has a cosmopolitan distribution, occurring on every continent except Antarctica. The beetle most likely originated in West Africa and moved around the globe with the trade of legumes and other crops. As only a small number of individuals were likely present in legumes carried by people to distant places, the populations that have invaded various parts of the globe have likely gone through multiple bottlenecks. Despite these bottlenecks and the subsequent rounds of inbreeding, these populations persist. This ability to withstand a high degree of inbreeding has likely contributed to this species’ prevalence as a pest.
WThe cat is a domestic species of small carnivorous mammal. It is the only domesticated species in the family Felidae and is often referred to as the domestic cat to distinguish it from the wild members of the family. A cat can either be a house cat, a farm cat or a feral cat; the latter ranges freely and avoids human contact. Domestic cats are valued by humans for companionship and their ability to hunt rodents. About 60 cat breeds are recognized by various cat registries.
WCiona intestinalis is an ascidian, a tunicate with very soft tunic. Its Latin name means, literally, "pillar of intestines", referring to the fact that its body is a soft, translucent column-like structure, resembling a mass of intestines sprouting from a rock. It is a globally distributed cosmopolitan species. Since Linnaeus described the species, Ciona intestinalis has been used as a model invertebrate chordate in developmental biology and genomics. Studies conducted between 2005 and 2010 have shown that there are at least two, possibly four, sister species. More recently it has been shown that one of these species has already been described as Ciona robusta. By anthropogenic means, the species has invaded various parts of the world and is known as an invasive species.
WThe common frog, also known as the European common frog, European common brown frog, or European grass frog, is a semi-aquatic amphibian of the family Ranidae, found throughout much of Europe as far north as Scandinavia and as far east as the Urals, except for most of Iberia, southern Italy, and the southern Balkans. The farthest west it can be found is Ireland. It is also found in Asia, and eastward to Japan.
WThe confused flour beetle, a type of darkling beetle known as a flour beetle, is a common pest insect known for attacking and infesting stored flour and grain. They are one of the most common and most destructive insect pests for grain and other food products stored in silos, warehouses, grocery stores, and homes.
WDaphnia magna is a small planktonic crustacean that belongs to the subclass Phyllopoda. It inhabits a variety of freshwater environments, ranging from acidic swamps to rivers made of snow runoff, and is broadly distributed throughout the Northern Hemisphere and South Africa.
WDaphnia pulex is the most common species of water flea. It has a cosmopolitan distribution: the species is found throughout the Americas, Europe and Australia. It is a model species, and was the first crustacean to have its genome sequenced.
WThe dog is a domesticated carnivore of the family Canidae. It is part of the wolf-like canids, and is the most widely abundant terrestrial carnivore. The dog and the extant gray wolf are sister taxa as modern wolves are not closely related to the wolves that were first domesticated, which implies that the direct ancestor of the dog is extinct. The dog was the first species to be domesticated, and has been selectively bred over millennia for various behaviors, sensory capabilities, and physical attributes.
WDrosophila is a genus of flies, belonging to the family Drosophilidae, whose members are often called "small fruit flies" or pomace flies, vinegar flies, or wine flies, a reference to the characteristic of many species to linger around overripe or rotting fruit. They should not be confused with the Tephritidae, a related family, which are also called fruit flies ; tephritids feed primarily on unripe or ripe fruit, with many species being regarded as destructive agricultural pests, especially the Mediterranean fruit fly.
WThe zebra finch is the most common estrildid finch of Central Australia and ranges over most of the continent, avoiding only the cool moist south and some areas of the tropical far north. It can also be found natively on Timor island. The bird has been introduced to Puerto Rico and Portugal.
WThe Japanese rice fish also known as the medaka, is a member of genus Oryzias (ricefish), the only genus in the subfamily Oryziinae. This small native of East Asia is a denizen of rice paddies, marshes, ponds, slow-moving streams and tide pools. It is euryhaline, occurring in both brackish and freshwater. It became popular as an aquarium fish because of its hardiness and pleasant coloration: its coloration varies from creamy-white to yellowish in the wild to white, creamy-yellow, or orange in aquarium-bred individuals. Bright yellow, red or green transgenic populations, similar to GloFish, have also been developed, but are banned from sale in the EU. The medaka has been a popular pet since the 17th century in Japan. After fertilization, the female carries her eggs attached anterior to the anal fin for a period before depositing them on plants or similar things.
WGerm-free organisms are multi-cellular organisms that have no microorganisms living in or on them. Such organisms are raised using various methods to control their exposure to viral, bacterial or parasitic agents. When known microbiota are introduced to a germ-free organism, it usually is referred to as a gnotobiotic organism, however technically speaking, germ-free organisms are also gnotobiotic because the status of their microbial community is known. Due to lacking a microbiome, many germ-free organisms exhibit health deficits such as defects in the immune system and difficulties with energy acquisition. Typically germ-free organisms are used in the study of a microbiome where careful control of outside contaminants is required.
WThe gray short-tailed opossum is a small South American member of the family Didelphidae. Unlike most other marsupials, the gray short-tailed opossum does not have a true pouch. The scientific name Monodelphis is derived from Greek and means "single womb" and the Latin word domestica which means "domestic". It was the first marsupial to have its genome sequenced. The gray short-tailed opossum is used as a research model in science, and is also frequently found in the exotic pet trade. It is also known as the Brazilian opossum, rainforest opossum and in a research setting the laboratory opossum.
WThe guinea pig or domestic guinea pig, also known as cavy or domestic cavy, is a species of rodent belonging to the family Caviidae and the genus Cavia. Despite their common name, guinea pigs are not native to Guinea, nor are they closely biologically related to pigs, and the origin of the name is still unclear. They originated in the Andes of South America. Studies based on biochemistry and hybridization suggest they are domesticated descendants of a closely related species of cavy, such as C. tschudii, and do not exist naturally in the wild. They were originally domesticated as livestock, for a source of meat, and continue to be consumed as food.
WThe Iberian ribbed newt, gallipato or Spanish ribbed newt is a newt endemic to the central and southern Iberian Peninsula and Morocco. It is the largest European newt species and it is also known for its sharp ribs which can puncture through its sides, and as such is also called the sharp-ribbed newt.
WThe rhesus macaque is a species of Old World monkey. It is listed as least concern in the IUCN Red List of Threatened Species in view of its wide distribution, presumed large population, and its tolerance of a broad range of habitats. It is native to South, Central, and Southeast Asia and has the widest geographic range of all non-human primates, occupying a great diversity of altitudes and a great variety of habitats, from grasslands to arid and forested areas, but also close to human settlements.
WManduca sexta is a moth of the family Sphingidae present through much of the American continent. The species was first described by Carl Linnaeus in his 1763 Centuria Insectorum.
WNippostrongylus brasiliensis is a type of nematode/gastrointestinal roundworm or nematode that infects rodents, primarily rats. This worm is a widely studied parasite due to its simple lifecycle and its ability to be used in animal models. Its lifecycle similar to the human hookworms Necator americanus and Ancylostoma duodenale which includes five molting stages to become sexually mature.
WThe northern leopard frog is a species of leopard frog from the true frog family, native to parts of Canada and the United States. It is the state amphibian of Minnesota and Vermont.
WOikopleura dioica is a species of small pelagic tunicate found in the surface waters of most of the world's oceans. It is used as a model organism in research into developmental biology.
WThe Ossabaw Island hog or Ossabaw Island is a breed of pig derived from a population of feral pigs on Ossabaw Island, Georgia, United States. The original Ossabaw hogs are descended from swine released on the island in the 16th century by Spanish explorers. A breeding population has been established on American farms off the island, but they remain a critically endangered variety of pig.
WParhyale hawaiensis is an amphipod crustacean species that is used in developmental and genetic analyses. It is categorized as an emerging model organism as the main biological techniques necessary for the study of an organism have been established.
WA planarian is one of many flatworms of the traditional class Turbellaria. It usually describes free-living flatworms of the order Tricladida (triclads), although this common name is also used for a wide number of free-living platyhelminthes. Planaria are common to many parts of the world, living in both saltwater and freshwater ponds and rivers. Some species are terrestrial and are found under logs, in or on the soil, and on plants in humid areas.
WPristionchus pacificus is a species of free-living nematodes (roundworms) in the family Diplogastridae. The species has been established as a satellite model organism to Caenorhabditis elegans, with which it shared a common ancestor 200-300 million years ago. The genome of P. pacificus has been fully sequenced, which in combination with other tools for genetic analysis make this species a tractable model in the laboratory, especially for studies of developmental biology.
WA domestic or domesticated rabbit —more commonly known as a pet rabbit, a bunny, a bun, or a bunny rabbit—is a subspecies of European rabbit. A domestic rabbit kept as a pet may be considered a pocket pet, depending on its size. A male rabbit is known as a buck, a female is a doe, and a young rabbit is a kit, or kitten.
WThe red flour beetle is a species of beetle in the family Tenebrionidae, the darkling beetles. It is a worldwide pest of stored products, particularly food grains, and a model organism for ethological and food safety research.
WSchmidtea mediterranea is a freshwater triclad that lives in southern Europe and Tunisia. It is a model for regeneration, stem cells and development of tissues such as the brain and germline.
WSea urchins, are typically spiny, globular animals, echinoderms in the class Echinoidea. About 950 species live on the seabed, inhabiting all oceans and depth zones from the intertidal to 5,000 metres. Their tests are round and spiny, usually from 3 to 10 cm across. Sea urchins move slowly, crawling with their tube feet, and sometimes pushing themselves with their spines. They feed primarily on algae but also eat slow-moving or sessile animals. Their predators include sea otters, starfish, wolf eels, triggerfish, and humans.
WThe Sebright is a British breed of bantam chicken. It is a true bantam – a miniature bird with no corresponding large version – and is one of the oldest recorded British bantam breeds. It is named after Sir John Saunders Sebright, who created it as an ornamental breed by selective breeding in the early nineteenth century.
WSpecific-pathogen-free (SPF) is a term used for laboratory animals that are guaranteed free of particular pathogens. Use of SPF animals ensures that specified diseases do not interfere with an experiment. For example, absence of respiratory pathogens such as influenza is desirable when investigating a drug's effect on lung function.
WThe starlet sea anemone is a species of small sea anemone in the family Edwardsiidae native to the east coast of the United States, with introduced populations along the coast of southeast England and the west coast of the United States. Populations have also been located in Nova Scotia, Canada. This sea anemone is found in the shallow brackish water of coastal lagoons and salt marshes where its slender column is usually buried in the mud and its tentacles exposed. Its genome has been sequenced and it is cultivated in the laboratory as a model organism, but the IUCN has listed it as being a "Vulnerable species" in the wild.
WSymsagittifera roscoffensis, also called the Roscoff worm, the mint-sauce worm, or the shilly-shally worm, is a marine flatworm belonging to the phylum of Xenacoelomorpha. The origin and nature of the green color of this worm stimulated the curiosity of zoologists early on. It is due to the partnership between the animal and a green micro-algae, the species Tetraselmis convolutae, hosted under its epidermis. It is the photosynthetic activity of the micro-algae in hospite that provides the essential nutrients for the worm. This partnership is called photosymbiosis, from "photo", "light", and symbiosis "who lives with". These photosynthetic marine animals live in colonies on the tidal zone.
WTakifugu rubripes, commonly known as the Japanese puffer, Tiger puffer, or torafugu, is a pufferfish in the genus Takifugu. It is distinguished by a very small genome that has been fully sequenced because of its use as a model species and is in widespread use as a reference in genomics.
WThe tammar wallaby, also known as the dama wallaby or darma wallaby, is a small macropod native to South and Western Australia. Though its geographical range has been severely reduced since European colonization, the tammar wallaby remains common within its reduced range and is listed as "Least Concern" by the International Union for Conservation of Nature (IUCN). It has been introduced to New Zealand and reintroduced to some areas of Australia where it had been previously eradicated. Skull differences distinguish tammar wallabies from Western Australia, Kangaroo Island, and mainland South Australia, making them distinct population groups or possibly different subspecies.
WThe western clawed frog is a species of frog in the family Pipidae, also known as tropical clawed frog. It is the only species in the genus Xenopus to have a diploid genome. Its genome has been sequenced, making it a significant model organism for genetics that complements the related species Xenopus laevis, a widely used vertebrate model for developmental biology. X. tropicalis also has a number of advantages over X. laevis in research, such as a much shorter generation time, smaller size, and a larger number of eggs per spawn.
WXenopus is a genus of highly aquatic frogs native to sub-Saharan Africa. Twenty species are currently described within it. The two best-known species of this genus are Xenopus laevis and Xenopus tropicalis, which are commonly studied as model organisms for developmental biology, cell biology, toxicology, neuroscience and for modelling human disease and birth defects.
WThe zebrafish is a freshwater fish belonging to the minnow family (Cyprinidae) of the order Cypriniformes. Native to South Asia, it is a popular aquarium fish, frequently sold under the trade name zebra danio.