
Squirrels are members of the family Sciuridae, a family that includes small or medium-size rodents. The squirrel family includes tree squirrels, ground squirrels, chipmunks, marmots, flying squirrels, and prairie dogs amongst other rodents. Squirrels are indigenous to the Americas, Eurasia, and Africa, and were introduced by humans to Australia. The earliest known fossilized squirrels date from the Eocene epoch, and among other living rodent families, the squirrels are most closely related to the mountain beaver and to the dormice.

Black squirrels are a melanistic subgroup of squirrels with black coloration on their fur. The phenomenon occurs with several species of squirrels, although it is most frequent with the eastern gray squirrel and the fox squirrel. Black morphs of the eastern gray and fox squirrels are the result of an abnormal pigment gene. Several theories have surfaced as to why the black morph occurs, with some suggesting that the black morph is a selective advantage for squirrels inhabiting the northern ranges of the species, with the black-fur providing a thermal advantage over its non-melanistic counterpart.

Tree squirrels are the members of the squirrel family (Sciuridae) commonly just referred to as "squirrels." They include more than 100 arboreal species native to all continents except Antarctica and Oceania.
A drey is the nest of a tree squirrel, flying squirrel or ringtail possum.Dreys are usually built of twigs, dry leaves, and grass, and typically assembled in the forks of a tall tree. They are sometimes referred to as "drey nests" to distinguish them from squirrel "cavity nests". In temperate regions, dreys become much more visible in the autumn, when leaf-fall reveals new nests built the previous summer or in early fall.

The Neotropical pygmy squirrel is a South American species of tree squirrel, being the only living species in the genus Sciurillus and the subfamily Sciurillinae. Genetic analysis has shown it to be the sister group to all other squirrels.

Squirrel fishing is the sporting practice of "catching" squirrels and attempting to lift them into the air using a nut tied to a string or fishing line, and optionally some kind of fishing pole.

Squirrelpox virus is a virus that causes the fatal disease squirrelpox in United Kingdom red squirrels. The virus is often carried by grey squirrels from North America, which rarely die from the disease. Elsewhere in the Red Squirrel's European range, either the grey squirrel does not occur or it lacks the poxvirus.

Tree squirrels are the members of the squirrel family (Sciuridae) commonly just referred to as "squirrels." They include more than 100 arboreal species native to all continents except Antarctica and Oceania.