
Texcoco was a major Acolhua altepetl (city-state) in the central Mexican plateau region of Mesoamerica during the Late Postclassic period of pre-Columbian Mesoamerican chronology. It was situated on the eastern bank of Lake Texcoco in the Valley of Mexico, to the northeast of the Aztec capital, Tenochtitlan. The site of pre-Columbian Texcoco is now subsumed by the modern Mexican municipio of Texcoco and its major settlement, the city formally known as Texcoco de Mora. It also lies within the greater metropolitan area of Mexico City.

Cacamatzin (1483–1520) was the tlatoani (ruler) of Texcoco, the second most important city of the Aztec Empire.

The Codex Xolotl is a postconquest cartographic Aztec codex, thought to have originated before 1542. It is annotated in Nahuatl and details the preconquest history of the Valley of Mexico, and Texcoco in particular, from the arrival of the Chichimeca under the king Xolotl in the year 5 Flint (1224) to the Tepanec War in 1427.

Ixtlilxochitl II was the son of Nezahualpilli, Tlatoani of Texcoco. In 1516 Nezahualpilli died, and the succession was contested by several of his sons, including Cacamatzin and Ixtlilxochitl. The former gained the support of Moctezuma II, Tlatoani of the Aztec Empire. A civil war ensued, and ended in a tripartite division of Tetzcoco, by which one third of the kingdom, with the capital, was awarded to Cacamatzin, the northern part to his brother Ixtlilxochitl, and the third part to another claimant to the throne. Ixtlilxochitl became from that time the enemy of Moctezuma II.

Ixtlilxochitl Ome Tochtli (1380-1418) was the ruler (tlatoani) of the Acolhua city-state of Texcoco from 1409 to 1418 and the father of the famous "poet-king" Nezahualcoyotl.

Nezahualpilli was ruler (tlatoani) of the Mesoamerican city-state of Texcoco, elected by the city's nobility after the death of his father, Nezahualcoyotl, in 1472.

Techotlalatzin was the ruler (tlatoani) of the pre-Columbian Mesoamerican city-state of Texcoco from 1357 or 1377 until his death in 1409. Techotlalatzin was the first ruler of the Acolhua who actively adopted the prevailing culture of the Valley of Mexico, including the Nahuatl language.

Texcotzingo is claimed to be one of the first extant botanical gardens in the Americas, along with Montezuma's gardens in Huastepec. The gardens and archaeological site are located roughly 20 miles northeast of central Mexico City, Mexico.