
Basseterre is the capital and largest city of Saint Kitts and Nevis with an estimated population of 14,000 in 2018. Geographically, the Basseterre port is located at 17°18′N 62°44′W, on the south western coast of Saint Kitts Island, and it is one of the chief commercial depots of the Leeward Islands. The city lies within Saint George Basseterre Parish.
Bridgetown is the capital and largest city of Barbados. Formerly The Town of Saint Michael, the Greater Bridgetown area is located within the parish of Saint Michael. Bridgetown is sometimes locally referred to as "The City", but the most common reference is simply "Town". As of 2014, its metropolitan population stands at roughly 110,000.

Charlotte Amalie, located on the island of St. Thomas, is the capital and the largest city of the United States Virgin Islands, founded in 1666 as Taphus. In 1691, the town was renamed to Charlotte Amalie after Charlotte Amalie of Hesse-Kassel (1650–1714), queen consort to King Christian V of Denmark-Norway. It has a deep-water harbor that was once a haven for pirates and is now one of the busiest ports of call for cruise ships in the Caribbean, with about 1.5 million/plus cruise ship passengers landing there annually. Protected by Hassel Island, the harbor has docking and fueling facilities, machine shops, and shipyards and was a U.S. submarine base until 1966. The Town has been inhabited for centuries. When Christopher Columbus arrived in 1493, the area was inhabited by Caribs, Arawaks, Ciboney and Taíno native peoples. It is on the southern shore at the head of Saint Thomas Harbor. In 2010 the City had a population of 18,481, which makes it the largest city in the Virgin Islands Archipelago. Hundreds of ferries and yachts pass by the Town each week.

The City of Hamilton, in Pembroke Parish, is the territorial capital of the British Overseas Territory of Bermuda. It is the territory's financial centre and a major port and tourist destination. Its population of 854 (2016) is one of the smallest of any capital cities.

Havana is the capital city, largest city, province, major port, and leading commercial center of Cuba. The city has a population of 2.1 million inhabitants, and it spans a total of 781.58 km2 (301.77 sq mi) – making it the largest city by area, the most populous city, and the fourth largest metropolitan area in the Caribbean region.

Kingston is the capital and largest city of Jamaica, located on the southeastern coast of the island. It faces a natural harbour protected by the Palisadoes, a long sand spit which connects the town of Port Royal and the Norman Manley International Airport to the rest of the island. In the Americas, Kingston is the largest predominantly English-speaking city south of the United States.

Managua is the capital and largest city of Nicaragua, and the center of an eponymous department. Located on the southwestern shore of Lake Managua and inside the Managua Department, it has an estimated population 1,042,641 in 2016 within the city's administrative limits and a population of 1,401,687 in the metropolitan area, which additionally includes the municipalities of Ciudad Sandino, El Crucero, Nindirí, Ticuantepe and Tipitapa.

Mexico City is the capital and largest city of Mexico and the most-populous city in North America. Mexico City is one of the most important cultural and financial centres in the world. It is located in the Valley of Mexico, a large valley in the high plateaus in the center of Mexico, at an altitude of 2,240 meters (7,350 ft). The city has 16 subdivisions, formerly known as boroughs.

Nuuk is the capital and largest city of Greenland. Nuuk is the seat of government and the country's largest cultural and economic centre. The major cities from other countries closest to the capital are Iqaluit and St. John's in Canada and Reykjavík in Iceland. Nuuk contains almost a third of Greenland's population and its tallest building. Nuuk is also the seat of government for the Sermersooq municipality. In January 2020, it had a population of 18,326.

Ottawa is the capital city of Canada. It stands on the south bank of the Ottawa River in the eastern portion of southern Ontario. Ottawa borders Gatineau, Quebec, and forms the core of the Ottawa–Gatineau census metropolitan area (CMA) and the National Capital Region (NCR). As of 2016, Ottawa had a city population of 934,243 and a metropolitan population of 1,323,783 making it the fourth-largest city and the fifth-largest CMA in Canada. In June 2019, the City of Ottawa estimated it had surpassed a population of one million.

Panama City, also simply known as Panama, is the capital and largest city of Panama. It has an urban population of 880,691, with over 1.5 million in its metropolitan area. The city is located at the Pacific entrance of the Panama Canal, in the province of Panama. The city is the political and administrative center of the country, as well as a hub for banking and commerce.

Port of Spain, officially the City of Port of Spain, is the capital city of Trinidad and Tobago and the country's second-largest city after San Fernando and the third largest municipality after Chaguanas and San Fernando. The city has a municipal population of 37,074, an urban population of 81,142 and a transient daily population of 250,000. It is located on the Gulf of Paria, on the northwest coast of the island of Trinidad and is part of a larger conurbation stretching from Chaguaramas in the west to Arima in the east with an estimated population of 600,000.

Port-au-Prince is the capital and most populous city of Haiti. The city's population was estimated at 987,310 in 2015 with the metropolitan area estimated at a population of 2,618,894. The metropolitan area is defined by the IHSI as including the communes of Port-au-Prince, Delmas, Cite Soleil, Tabarre, Carrefour and Pétion-Ville.

Road Town, located on Tortola, is the capital of the British Virgin Islands. It is situated on the horseshoe-shaped Road Harbour in the centre of the island's south coast. The population was about 15,000 in 2018.

Roseau is the capital and largest city of Dominica, with a population of 14,725 as of 2011. It is a small and compact urban settlement, in the Saint George parish and surrounded by the Caribbean Sea, the Roseau River and Morne Bruce. Built on the site of the ancient Island Carib village of Sairi, it is the oldest and most important urban settlement on the island of Dominica.

St. George's is the capital of Grenada. The town is surrounded by a hillside of an old volcano crater and is on a horseshoe-shaped harbour.
Saint-Pierre is the capital of the French overseas collectivity of Saint Pierre and Miquelon, off the coast of Newfoundland in Canada. Saint-Pierre is the more populated of the two communes (municipalities) making up Saint Pierre and Miquelon.

San José is the capital and largest city of Costa Rica, and the capital of the province of the same name. It is in the centre of the country, in the mid-west of the Central Valley, within San José Canton. San José is Costa Rica's seat of national government, focal point of political and economic activity, and major transportation hub. San José Canton's population was 288,054 in 2011, and San José's municipal land area is 44.2 square kilometers, with an estimated 333,980 residents in 2015. Together with several other cantons of the central valley, including Alajuela, Heredia and Cartago, it forms the country's Greater Metropolitan Area, with an estimated population of over 2 million in 2017. The city is named in honor of Joseph of Nazareth.

San Juan is the capital and most-populous municipality in the Commonwealth of Puerto Rico, an unincorporated territory of the United States. As of the 2010 census, it is the 46th-largest city under the jurisdiction of the United States, with a population of 395,326. San Juan was founded by Spanish colonists in 1521, who called it Ciudad de Puerto Rico. Puerto Rico's capital is the third oldest European-established capital city in the Americas, after Santo Domingo, in the Dominican Republic, founded in 1496, and Panama City, in Panama, founded in 1521, and is the oldest European-established city in the U.S. proper or U.S. territories. Several historical buildings are located in San Juan; among the most notable are the city's former defensive forts, Fort San Felipe del Morro and Fort San Cristóbal, and La Fortaleza, the oldest executive mansion in continuous use in the Americas.

San Salvador is the capital and the most populous city of El Salvador and its eponymous department. It is the country's political, cultural, educational and financial center. The Metropolitan Area of San Salvador, which comprises the capital itself and 13 of its municipalities, has a population of 2,404,097.

St. John's is the capital and largest city of Antigua and Barbuda, part of the West Indies in the Caribbean Sea. With a population of 22,219, St. John's is the commercial centre of the nation and the chief port of the island of Antigua.

Tegucigalpa, formally Tegucigalpa, Municipality of the Central District, and colloquially referred to as Tegus or Teguz, is the capital and largest city of Honduras along with its twin sister, Comayagüela.

Washington, D.C., formally the District of Columbia and also known as D.C. or Washington, is the capital city of the United States of America. Founded after the American Revolution, Washington was named for George Washington, the first president of the United States and a Founding Father. As the seat of the United States federal government and several international organizations, Washington is an important world political capital. Located on the Potomac River bordering Maryland and Virginia, the city is one of the most visited cities in the United States, with more than 20 million visitors annually.