
The Seven Noble Houses of Brussels were the seven families or clans whose descendants formed the patrician class and urban aristocracy of Brussels.

Amsinck is a Dutch-origined patrician family whose members were prominent merchants in multiple countries including the Netherlands, Hamburg, Portugal, England, France, Hanover, Holstein, Denmark, Suriname and India. From the 17th century the Hamburg branch of the family formed part of the city-state's ruling class, the Hanseaten or hereditary grand burghers, who enjoyed legal privileges in Hamburg until 1918. Amsinck has been one of Hamburg's great business families over many centuries, and its members reached the highest positions in Hamburg society, including as senators and head of state. A branch of the family were large plantation owners in Suriname. The Hamburg branch retained a Dutch identity for centuries, often intermarrying with other Dutch-origined patrician families.

Arrazola de Oñate is a Belgian noble family, stemming from the Arrazola family in the city of Oñati in the Basque Country. Since the 17th century a branch has been living in the Spanish Netherlands, later to become the United Kingdom of the Netherlands and Belgium, holding high functions ranging from the military to feudal lords and councilors.

Guillaume Delcourt was a Belgian Royal Navy officer, navigator, naval engineer, and maritime advisor to King Leopold II. He was one of the major players of early Belgian expansion around the world.

The House or Lineage of Coudenbergh or Coudenberg is one of the Seven Noble Houses of Brussels along with the Houses of: Sleeus, Serhuyghs, Steenweeghs, Sweerts, Serroelofs, and Roodenbeke.

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The House of Serhuyghs or Serhuyghs Lineage is one of the Seven Noble Houses of Brussels along with the Houses of: Sleeus, Roodenbeke, Sweerts, Serroelofs, Steenweeghs, and Coudenberg.

The House or Lineage of Serroelofs or t’Serroelofs is one of the Seven Noble Houses of Brussels along with the Houses of: Sleeus, Serhuyghs, Steenweeghs, Sweerts, Coudenberg, and Roodenbeke.

The House of Sleeus or Sleeus Lineage is one of the Seven Noble Houses of Brussels along with the Houses of: Roodenbeke, Serhuyghs, Steenweeghs, Sweerts, Serroelofs, and Coudenberg.

The House of Sweerts or Sweerts Lineage is one of the Seven Noble Houses of Brussels along with the Houses of: Sleeus, Serhuyghs, Steenweeghs, Coudenbergh, Serroelofs and Roodenbeke.

t'Kint de Roodenbeke is a bourgeois and noble family from Belgium. They are the current owners of the Ooidonk Castle in the city of Deinze, East Flanders.

The House of Lalaing is a noble family from the south of Flanders which played an important role in the history of the County of Hainaut and of the Netherlands.

The Leyniers family (/lɛnɪjɛ/) is a bourgeois family that appeared in Brussels in the 15th century and produced many high-level tapestry makers and dyers, experts in the art of dyeing in subtle shades the woolen threads destined for this trade.

Frederick de Marselaer (1584–1670) was a mayor of Brussels and the author of a treatise on diplomacy.

The de Muyser Lantwyck family is an old Belgian family dating back to the beginning of the 15th century, tracing its roots to Jean Moyser, alderman of Vaelbeek, who held lands in Héverlé in 1451, censier of the Groenendael Priory, lord holding the lands and manor of Cockelberg by lease dated 19 June 1438, husband of Aleyde Crabbé.

The House of van der Noot is a Belgian Noble family.

The Pipenpoy family (/pɪpɒ̃pwə/), was an old and influential patrician family of Brussels which exercised public functions in the capital of the Duchy of Brabant until the end of the Ancien Régime. It died in 1832 with Catherine de Pipenpoy, who was 100 years old. Several of its members were admitted to the Seven Noble Houses of Brussels.

The Poot family is a family that was admitted to the bourgeoisie of Brussels and from 1753 was registered among the Seven Noble Houses of Brussels.

The House of Steenweeghs or Steenweeghs Lineage is one of the Seven Noble Houses of Brussels, along with Roodenbeke, Sleeus, Serhuyghs, Sweerts, Serroelofs and Coudenberg.

The Van Dievoet family is a Belgian family originating from the Duchy of Brabant. It descends from the Seven Noble Houses of Brussels and its members have been bourgeois (burgess) of that city since the 1600s. It formed, at the end of the 17th century, a now extinct noble Parisian branch called Vandive.

Henri van Dievoet was a Belgian architect.

The Wittouck family (/witʊk/) is a noble Belgian family, that descends from the Seven Noble Houses of Brussels, established in Brussels since the 18th century.
Guillaume Wittouck was a Belgian lawyer and High Magistrate. He was the Grandfather of industrialist Paul Wittouck and of Belgian navigator Guillaume Delcourt.