
Alexandria Bucephalous, was a city founded by Alexander the Great in memory of his beloved horse Bucephalus. Founded in May 326 BC, the town was located on the Hydaspes, east of the Indus River. Bucephalus had died after the Battle of the Hydaspes in 326 BC. The garrison was settled with Greek and Iranian veterans and Pauravas locals. It had large dockyards, suggesting it was intended as a center of commerce.

Alexandria in Orietai was one of the seventy-plus cities founded or renamed by Alexander the Great.

Alexandria on the Indus was a city founded by Alexander the Great at the junction of the Indus and the Acesines river. Arrian tells that colonists, mainly Thracian veterans and natives, were settled there.
Amri is an ancient settlement in modern-day Sindh, Pakistan, that goes back to 3600 BCE. The site is located south of Mohenjo Daro on Hyderabad-Dadu Road more than 100 kilometres north of Hyderabad, Pakistan.

Barbarikon was the name of a sea port near the modern-day city of Karachi, Sindh, Pakistan, important in the ancient era of the Indian subcontinent in Indian Ocean trade. The port is considered one of the premiere ports regarding the interaction between ancient India with the Middle East and Mediterranean world. It comes from the Greek word of the term, designating areas outside the civilization and/or the Roman Empire and the Greek world.

The Bhir Mound is an archaeological site in Taxila in the Punjab province of Pakistan. It contains some of the oldest ruins of Ancient Taxila, dated to sometime around the period 800-525 BCE as its earliest layers bear "grooved" Red Burnished Ware, Bhir Mound, along with several other nearby excavations, form part of the Ruins of Taxila – inscribed as a UNESCO World Heritage Site in 1980.

Chanhu-daro is an archaeological site belonging to the Indus Valley Civilization. The site is located 130 kilometers (81 mi) south of Mohenjo-daro, in Sindh, Pakistan. The settlement was inhabited between 4000 and 1700 BCE, and is considered to have been a centre for manufacturing carnelian beads. This site is a group of three low mounds that excavations has shown were parts of a single settlement, approximately 5 hectares in size.

Debal was an ancient port located near modern Karachi, Pakistan. It is adjacent to the nearby Manora Island and was administered by Mansura, and later Thatta.

Ganweriwala is an Indus Valley Civilization site in the Cholistan Desert of southern Punjab, Pakistan.

Harappa is an archaeological site in Punjab, Pakistan, about 24 km (15 mi) west of Sahiwal. The site takes its name from a modern village located near the former course of the Ravi River which now runs 8 km (5.0 mi) to the north. The current village of Harappa is less than 1 km (0.62 mi) from the ancient site. Although modern Harappa has a legacy railway station from the British Raj period, it is a small crossroads town of 15,000 people today.

Jaulian is a ruined Buddhist monastery dating from the 2nd century CE, located in Pakistan. Jaulian is located in Haripur District, Khyber Pakhtunkhwa province, near the provincial border with Punjab and the city of Taxila.

Kolachi was also a port located at modern Karachi and the old name of Karachi, Sindh, Pakistan. According to legends, it was a port developed when an old fisherwoman by the name of Mai Kolachi settled near the delta of the Indus River to start a community. One of the main Flyover (overpass) in Karachi has been named after Mai Kolachi. This settlement was also known as "Kolachi jo Goth" or "the village of the Kolachi".

The ancient site at Kot Diji was the forerunner of the Indus Civilization. The occupation of this site is attested already at 3300 BCE. The remains consist of two parts; the citadel area on high ground, and outer area. The Pakistan Department of Archaeology excavated at Kot Diji in 1955 and 1957.

Lakhan-jo-daro is an archeological site and one of the largest cities of the Indus Valley Civilization. It is located within an industrial zone on the outskirts of the modern city of Sukkur and situated at the distance of mere 75 Kilometers from another major city of its contemporary era, Mohenjo Daro. It covers an expanse of more than 300 Hectares.

Mansura, referred to as "Brahmnabad" in later centuries, was the historic capital of the Muslim Caliphate in Sindh, during the eighth century under the Umayyad Caliphate and then Abbasid Caliphate from the year 750 AD to 1006 AD. The city was founded as a central garrison by the Umayyad Forces in Sindh, the city transformed into a very vibrant metropolis during the Abbasid Era surpassing the wealth of Multan in the north and Debal in the south. Mansura was built on the shores of the Indus River, it was surrounded by fertile farmland, Ibn Hauqal mentioned the wealthy local merchants who wore Baghdad Costume and were of Sindhi-Arab origins, houses were made of clay, baked bricks and plaster.

Mehrgarh is a Neolithic site, which lies on the Kacchi Plain of Balochistan, Pakistan. Mehrgarh is located near the Bolan Pass, to the west of the Indus River valley and between the present-day Pakistani cities of Quetta, Kalat and Sibi. The site was discovered in 1974 by an archaeological team directed by French archaeologists Jean-François Jarrige and Catherine Jarrige, and was excavated continuously between 1974 and 1986, and again from 1997 to 2000. Archaeological material has been found in six mounds, and about 32,000 artifacts have been collected. The earliest settlement at Mehrgarh—in the northeast corner of the 495-acre (2.00 km2) site—was a small farming village dated between 7000 BCE and 5500 BCE.

Minnagara was a city of the Indo-Scythian kingdom, located on the Indus river in modern Pakistan, north of the coastal city of Barbaricum, or along the Narmada river, upstream of Barygaza. There were two cities named Minnagara, one on Indus River delta near Karachi and the other at Narmada River delta near modern Bharuch.
Mohenjo-daro is an archaeological site in the province of Sindh, Pakistan. Built around 2500 BCE, it was one of the largest settlements of the ancient Indus Valley Civilisation, and one of the world's earliest major cities, contemporaneous with the civilizations of ancient Egypt, Mesopotamia, Minoan Crete, and Norte Chico. Mohenjo-daro was abandoned in the 19th century BCE as the Indus Valley Civilization declined, and the site was not rediscovered until the 1920s. Significant excavation has since been conducted at the site of the city, which was designated a UNESCO World Heritage Site in 1980. The site is currently threatened by erosion and improper restoration.

Pirak is an archaeological site belonging to the Indus Valley Civilization located in Balochistan, Pakistan. It is 20 km south of Sibi east of the Nari River. The mound is 8m high and covers approximately 12 acres (49,000 m2). The site of Pirak was first reported by Robert Raikes in 1963. It was excavated, between 1968 and 1974, before the well known sites of Mehrgarh or Nausharo by the French archaeological mission team led by Jean Marie Casal. According to the excavator, this site was occupied from c.1800 BCE to 800 BCE.
Pushkalavati IAST: Puṣkalāvatī, Greek: Peukelaotis), and later Shaikhan Dheri, was the capital of the Gandhara kingdom. Its ruins are located on the outskirts of the modern city of Charsadda, in Charsadda District, in the Khyber Pakhtunkhwa, 28 kilometres northeast of Peshawar. Its ruins are located on the banks of Swat River, near its junction with Kabul River, with the earliest archaeological remains from 1400 to 800 BCE in Bala Hisar mound. Pushkalavati was the capital of the ancient Gandhara kingdom before the 6th century BCE. It later became an Achaemenid regional capital, and it remained an important city until the 2nd century CE.

Rehman Dheri or sometime Rahman Dheri is a Pre-Harappan Archaeological Site situated near Dera Ismail Khan in the Khyber Pakhtunkhwa province of Pakistan. This is one of the oldest urbanised centres found to date in South Asia. Dated about 3300 BC, the site is situated 22 kilometres (14 mi) north of Dera Ismail Khan.

Sagala, Sakala, or Sangala was a city in ancient India, which was the predecessor of the modern city of Sialkot that is located in what is now Pakistan's northern Punjab province. The city was the capital of the Madra Kingdom and it was razed in 326 BC during the Indian campaign of Alexander the Great. In the 2nd century BC, Sagala was made capital of the Indo-Greek kingdom by Menander I. Menander embraced Buddhism after extensive debating with a Buddhist monk, as recorded in the Buddhist text Milinda Panha. Sagala became a major centre for Buddhism under his reign, and prospered as a major trading centre.

Shahbaz Garhi, or Shahbazgarhi, is a village and historic site located in Mardan District in the North West Frontier Province of Pakistan. It has an altitude of 293 metres.

Sirkap is the name of an archaeological site on the bank opposite to the city of Taxila, Punjab, Pakistan.
Sirsukh is an ancient city that forms part of the ruins at Taxila, near the modern day city of Taxila, Punjab, Pakistan.

Sokhta Koh is a Harappan site on the Makran coast, near the city of Pasni, in the Balochistan province of Pakistan. It was first surveyed by American archaeologist George F. Dales in 1960, while exploring estuaries along the Makran coast. The site is located about 15 miles north of Pasni. A similar site at Sutkagen-dor lies about 48 km (30 mi) inland, astride Dasht River, north of Jiwani. Their position along a coastline goes well with evidence of overseas commerce in Harappan times. Based on pottery styles, it is estimated that the settlement belongs to the Mature Harappan (Integration) Era.

Sutkagan Dor is the westernmost known archaeological site of the Indus Valley Civilization. It is located about 480 km west of Karachi on the Makran coast near Gwadar, close to the Iranian border, in Pakistan's Baluchistan Province. The site is near the western bank of the Dasht River and its confluence with a smaller stream, known as the Gajo Kaur. It was a smaller settlement with substantial stone walls and gateways.

Takht-i-Bahi, commonly mispronounced as Takht-i-Bhai, is an Indo-Parthian archaeological site of an ancient Buddhist monastery in Mardan, Khyber-Pakhtunkhwa, Pakistan. The site is considered among the most imposing relics of Buddhism in all of Gandhara, and has been "exceptionally well-preserved."

Taxila in Sanskrit is a significant archaeological site in the modern city of the same name in Punjab, Pakistan. It lies about 32 km (20 mi) north-west of Islamabad and Rawalpindi, just off the famous Grand Trunk Road.

Tibba Talwara is an archaeological site in Lodhran District, Punjab, Pakistan, about 5 km (3.1 mi) east of Lodhran.

Uch, frequently referred to as Uuch Sharīf, is an historic city in the southern part of Pakistan's Punjab province. .Uch may have been founded as Alexandria on the Indus, a town founded by Alexander the Great during his invasion of the Indus Valley. Uch was an early stronghold of the Delhi Sultanate during the Muslim conquest of the subcontinent. Also known as home for the Naqvi/Bukhari’s after the migration from Bukhara .Uch was a regional metropolitan centre between the 12th and 17th centuries, and became refuge for Muslim religious scholars fleeing persecution from other lands. Though Uch is now a relatively small city, it is renowned for intact historic urban fabric, and for its collection of shrines dedicated to Muslim mystics from the 12-15th centuries that are embellished with extensive tile work, and were built in the distinct architectural style of southern Punjab.