
Baconao Park is a large park region, located about 60 kilometers away from the city of Santiago de Cuba, with a total surface of 848.57 km2 (327.63 sq mi).
The Cauto River or Río Cauto is the longest river of Cuba, as well as the longest river in the Caribbean. Located in southeast Cuba, it is one of two navigable rivers in Cuba, with the other being the Sagua la Grande River.

Nipe-Sagua-Baracoa, also known as Macizo Nipe Sagua Baracoa, is a mountain range of eastern Cuba.

Pico Turquino is the highest point in Cuba. It is located in the southeast part of the island, in the Sierra Maestra mountain range in the municipality of Guamá, Santiago de Cuba Province.

San Juan Hill is a series of hills to the east of Santiago, Cuba, running north to south. The area is known as the San Juan Heights or in Spanish Alturas de San Juan before Spanish–American War of 1898, and are now part of Lomas de San Juan.

Sierra Maestra is a mountain range that runs westward across the south of the old Oriente Province in southeast Cuba, rising abruptly from the coast. The Sierra Maestra itself is located mainly in Santiago de Cuba Province and in Granma Province. Some view it as a series of connecting ranges, which joins with others extending to the west. The Sierra Maestra is the highest area of Cuba. It is rich in minerals, especially copper, manganese, chromium, and iron. At 1,974 m (6,476 ft), Pico Turquino is the range's highest point.

Turquino National Park, also known as Sierra Maestra National Park, is a national park in Santiago de Cuba Province, southeastern Cuba.