
The Balanta are an ethnic group found in Guinea-Bissau, Guinea, Senegal and The Gambia. They are the largest ethnic group of Guinea-Bissau, representing more than one-quarter of the population. Despite their numbers, they have remained outside the colonial and postcolonial state because of their social organisation. The Balanta can be divided into four subgroups: Balanta Nhacra, Balanta Ganja, Balanta Mane, and Balanta Kentohe, the largest of which are the Balanta Kentohe.

The Biafada people is an ethnic group of Guinea-Bissau, Senegal and Gambia. This group is often considered as a subgroup of the Tenda people. They are also known as Beafada, Biafar, Bidyola, Dfola, Dyola, Fada, and Yola.

The Fula, Fulani, or Fulɓe people are one of the largest ethnic groups in the Sahel and West Africa, widely dispersed across the region. Inhabiting many countries, they live mainly in West Africa and northern parts of Central Africa but also in South Sudan, Sudan, and regions near the Red Sea coast. The approximate number of Fula people is unknown due to clashing definitions regarding Fula ethnicity; various estimates put the figure between 35 and 45 million worldwide.

The Mandinka, or Malinke, are a West African ethnic group primarily found in southern Mali, eastern Guinea and northern Ivory Coast. Numbering about 11 million, they are the largest subgroup of the Mandé peoples and one of the largest ethnic groups in Africa. They speak the Mandinka language, which is one of the Western Manding languages in the Mande language family and a lingua franca in much of West Africa. Over 99% of Mandinka adhere to Islam. They are predominantly subsistence farmers and live in rural villages. Their largest urban center is Bamako, the capital of Mali, which is also inhabited by the closely related Bambara.

The Manjaks or Manjacks are an ethnic group in Guinea-Bissau with small Manjago comunities also present as far north as The Gambia. The Manjak endonym manjaku literally means "I tell you".
The Oku people or the Aku Marabout or Aku Mohammedans are an ethnic group in Sierra Leone and the Gambia primarily the descendants of educated, liberated Yoruba Muslims from Southwest Nigeria, who were released from slave ships and resettled in Sierra Leone as liberated Africans or came as settlers in the mid-19th century. Some Oku historically have intermarried since then with the ethnic Creole people. The Creole were primarily descendants of African-American former slaves, as well as some from Jamaica, and slaves liberated from illegal slave trading in the 19th century. The Oku people primarily reside in the communities of Fourah Bay, Fula Town, and Aberdeen and the official cemetery primarily used by the Oku people is the Aku Mohammedan Cemetery.

The Soninke people are a West African Mande ethnic group found in eastern Senegal and its capital Dakar, northwestern Mali and Fouta Djallon in Guinea, The Gambia and southern Mauritania. They speak the Soninke language, also called Maraka language, which is one of the Mande languages. Soninke people were the founders of the ancient empire of Ghana c. 750–1240 CE. Subgroups of Soninke include the Maraka and Wangara. When the Ghana empire was destroyed, the resulting diaspora brought Soninkes to Mali, Senegal, Mauritania, Gambia, Burkina Faso, Ghana, and Guinea-Bissau where some of this trading diaspora was called Wangara.

The Wolof people are a West African ethnic group found in northwestern Senegal, the Gambia, and southwestern coastal Mauritania. In Senegal, the Wolof are the largest ethnic group (~43.3%), while elsewhere they are a minority. They refer to themselves as Wolof and speak the Wolof language, in the West Atlantic branch of the Niger–Congo family of languages..