
National parks in Panama include:

The Volcán Barú is an active stratovolcano and the tallest mountain in Panama, at 3,474 metres (11,398 ft) high. It lies about 35 km (22 mi) off the border of Costa Rica. It is also the twelfth highest peak in Central America.

The Chagres National Park is located between the Province of Panama and Colon, in the Eastern sector of the Panama Canal with a total surface area of 129,000 hectares.
Coiba is the largest island in Central America, with an area of 503 km2 (194 sq mi), off the Pacific coast of the Panamanian province of Veraguas. It is part of the Montijo District of that province.

Darién National Park is a world heritage site in Panama. It is about 325 kilometers from Panama City, and is the most extensive of all national parks of Panama and is one of the most important world heritage sites in Central America.
The Gulf of Chiriquí National Marine Park is located in the Gulf of Chiriquí, on the Pacific coast of Panama. It was established in 1994 to protect 150 square kilometres (58 sq mi) of marine ecosystems, including coral reef, mangrove swamp and marine meadow, and around two dozen islands of the archipelago of Isla Parida. In total, the park has 25 islands and 19 coral reefs.

Isla Bastimentos National Marine Park is a marine park located in the Bocas del Toro Archipelago, Panama. The park covers 13,226 hectares.

The La Amistad International Park, or in Spanish Parque Internacional La Amistad, formerly the La Amistad National Park, is a Transboundary Protected Area in Latin America, management of which is shared between Costa Rica and Panama, following a recommendation by UNESCO after the park's inclusion in the World Heritage Site list.

Soberanía National Park is a national park in Panama near the banks of the Panama Canal in the provinces of Panamá and Colón, some 25 kilometres (16 mi) from Panama City. The Chagres River runs through the park. Established as a national park in 1980, the park covers 55,000 acres (220 km2).