
A for Andromeda is a British television science fiction drama serial first made and broadcast by the BBC in seven parts in 1961. Written by cosmologist Fred Hoyle, in conjunction with author and television producer John Elliot, it concerns a group of scientists who detect a radio signal from another galaxy that contains instructions for the design of an advanced computer. When the computer is built, it gives the scientists instructions for the creation of a living organism named Andromeda, but one of the scientists, John Fleming, fears that Andromeda's purpose is to subjugate humanity.

The Age of the Pussyfoot is a science fiction novel by American writer Frederik Pohl, first published as a serial in Galaxy Science Fiction in three parts, starting in October 1966. It was later published as a standalone novel in 1969.

Brainiac is a supervillain appearing in American comic books published by DC Comics. Created by Otto Binder and Al Plastino, the character debuted in Action Comics #242 in July 1958. He is usually depicted as an extraterrestrial android or cyborg who serves as one of Superman's greatest enemies and a frequent adversary of the Justice League. Brainiac is known for shrinking and stealing Kandor, the capital city of Superman's home planet Krypton, and is even responsible for Krypton's destruction in some continuities.

Cerebro is a fictional device appearing in American comic books published by Marvel Comics. The device is used by the X-Men to detect humans, specifically mutants. It was created by Professor X and Magneto, and was later enhanced by Dr. Hank McCoy.

Chi is a fictional character in the manga series Chobits and its anime adaptation. Chi is a Chobit, a type of personal computer called a persocom that is far more technologically advanced than regular persocoms, and who are said to possess true machine intelligence rather than relying on software programs like other persocoms. She is found by Hideki, a high school graduate who has no idea about her unique abilities or of her past. Over the course of the series Hideki tries to discover what type of persocom Chi is, being told that she is something special. He finds her a job, and has to deal with her being kidnapped at one point. Chi learns about the things around her and what it means to be in love. At the end of the series, Chi finds the person "just for her", and her forgotten identity is revealed, causing Hideki to confront his feelings.

Colby's Clubhouse is an American Christian children's television show that teaches principles from the Bible; through songs and everyday situations. The main character is Colby, an anthropomorphic computer that teaches children Christian principles and lessons. Colby has the entire Bible programmed into his memory. The show was written and produced by Peter and Hanneke Jacobs and was originally aired on Trinity Broadcasting Network, with Peter playing the part of Colby. It originally aired from 1995 to 2000 with several changes of cast members. The first episode aired on November 19, 1995, and it was last aired on December 31, 2000. On December 30, 2006, the show was removed from TBN, although it remains on the network's Smile of a Child digital subchannel. Albums and videotapes featuring Colby the Computer were produced. However, many of these were produced before the TBN series and feature different children.

Colossus: The Forbin Project is a 1970 American science fiction thriller film from Universal Pictures, produced by Stanley Chase, directed by Joseph Sargent, that stars Eric Braeden, Susan Clark, Gordon Pinsent, and William Schallert.

Cybergirl is an Australian children's television series that first screened on Network Ten in Australia. The 26-episode series was created by Jonathan M. Shiff, whose previous series include the BAFTA-award-winning Ocean Girl. Cybergirl has also screened on ABC on 6:00am, Thursday and on other networks outside Australia. In 2007 it aired as Cy-An 6000 on the Kabillion on-demand network but no reason is given for the name change.

Demon Seed is a 1977 American science fiction–horror film directed by Donald Cammell. It stars Julie Christie and Fritz Weaver. The film was based on the 1973 novel of the same name by Dean Koontz, and concerns the imprisonment and forced impregnation of a woman by an artificially intelligent computer. Gerrit Graham, Berry Kroeger, Lisa Lu and Larry J. Blake also appear in the film, with Robert Vaughn uncredited as the voice of the computer.

Egg Fu is a fictional character appearing in DC Comics publications and related media, commonly as an adversary of the superhero Wonder Woman. Most frequently represented as an enormous sentient egg, he was created by Robert Kanigher and Ross Andru in Wonder Woman, vol. 1, issue #157. Over the years, multiple versions of the character have appeared with varying backstories and alternative names to battle not only Wonder Woman, but also the Metal Men, Checkmate and Harley Quinn.

The Engine is a fictional device described in the 1726 satirical novel Gulliver's Travels by Jonathan Swift. It is possibly the earliest known reference to a device in any way resembling a modern computer.

"The General" is an episode of the allegorical British science fiction TV series, The Prisoner. It was written by "Joshua Adam" – a pseudonym for Lewis Greifer – and directed by Peter Graham Scott and the tenth to be produced. It was the sixth episode to be broadcast in the UK on ITV on Friday 3 November 1967 and first aired in the United States on CBS on Saturday 13 July 1968.

GLaDOS is a fictional artificially superintelligent computer system from the video game series Portal. GLaDOS later appeared in The Lab and Lego Dimensions. The character was created by Erik Wolpaw and Kim Swift and voiced by Ellen McLain. GLaDOS is responsible for testing and maintenance in the Aperture Science Computer-Aided Enrichment Center in all titles. While GLaDOS initially appears in the first game to simply be a voice that guides the player, her words and actions become increasingly malicious as she makes her intentions clear. The second game, as well as the Valve-created comic Lab Rat, reveals that she was mistreated by the scientists and used a neurotoxin to kill the scientists in the laboratory before the events of Portal. She is apparently destroyed at the end of the first game but returns in the sequel, in which she is comically supplanted and temporarily stuck on a potato battery.

The Hitchhiker's Guide to the Galaxy is a fictional electronic guide book in the multimedia scifi/comedy series of the same name by Douglas Adams. The Guide serves as "the standard repository for all knowledge and wisdom" for many members of the series' galaxy-spanning civilization. Entries from the guidebook are used as comic narration to bridge events and provide background information in every version of the story. The guide is published by "Megadodo Publications", a publishing company on Ursa Minor Beta.

Holly is a fictional character in the science fiction situation comedy Red Dwarf. The character, who is the eponymous spaceship's onboard computer, has been played by Norman Lovett and Hattie Hayridge.

Mother Boxes are fictional devices in Jack Kirby's Fourth World setting in the DC Universe.

Mother Brain is a fictional character created by Nintendo for the Metroid series. She is one of the most prominent antagonists within the series, serving as the main antagonist of Metroid and Super Metroid.

The Mysterons are a fictional race of extraterrestrials and the antagonists in the 1960s British Supermarionation science-fiction television series Captain Scarlet and the Mysterons (1967–68) and its 2005 computer-animated remake, Gerry Anderson's New Captain Scarlet. They are the remnants of the original Mysteron race: alien beings that originated in a galaxy other than the Milky Way and maintained a colony on Mars. They are symbolised by ubiquitous, projected green rings of light and the deep bass voice of their human convert Captain Black.

The Pip-Boy is a fictional wearable computer in the post-apocalyptic Fallout video game franchise. Manufactured in-universe by RobCo Industries prior to the devastating nuclear Great War, it is capable of numerous functions depending on the model. In the Fallout games, it functions as a diegetic way for the player to access the menu and manage their inventory.

Sheldon J. Plankton and Karen Plankton are fictional characters and the main antagonists in the Nickelodeon animated television series SpongeBob SquarePants. They are respectively voiced by Mr. Lawrence and Jill Talley. Their first appearance was in the episode "Plankton!" that premiered on July 31, 1999. They were created and designed by marine biologist and animator Stephen Hillenburg, the creator of the series. Hillenburg named Karen after his wife, Karen Umland.

SHODAN is a fictional artificial intelligence and the main antagonist of the cyberpunk-horror themed video games System Shock and System Shock 2.

Skynet is a fictional artificial neural network-based conscious group mind and artificial general superintelligence system that serves as the antagonistic force of the Terminator franchise.

Digital Fortress is a techno-thriller novel written by American author Dan Brown and published in 1998 by St. Martin's Press. The book explores the theme of government surveillance of electronically stored information on the private lives of citizens, and the possible civil liberties and ethical implications of using such technology.

This Perfect Day is a science fiction novel by American writer Ira Levin, about a technocratic dystopia. Levin won a Prometheus Award in 1992 for this novel. This Perfect Day is one of two Levin novels yet to be adapted to film.

When HARLIE Was One is a 1972 science fiction novel by American writer David Gerrold. It was nominated for the Nebula Award for Best Novel in 1972 and the Hugo Award for Best Novel in 1973. The novel, a "fix-up" of previously published short stories, was published as an original paperback by Ballantine Books in 1972, with an accompanying Science Fiction Book Club release. A revised version, subtitled "Release 2.0", was published in 1988 by Bantam Books.

WarGames is a 1983 American Cold War science fiction techno-thriller film written by Lawrence Lasker and Walter F. Parkes and directed by John Badham. The film, which stars Matthew Broderick, Dabney Coleman, John Wood, and Ally Sheedy, follows David Lightman (Broderick), a young hacker who unwittingly accesses a United States military supercomputer programmed to predict and execute nuclear war against the Soviet Union.

Saban's Xyber 9: New Dawn is an animated television series produced by Bokabi and Saban Entertainment. It originally debuted on the Fox Kids network on September 25, 1999. Only 10 episodes aired before it was cancelled on December 4, 1999. Soon after, it was aired in its entirety on Irish television network RTÉ Two from 2 July to August 2001. Six years later, it appeared on Toon Disney as part of the channel's Jetix line up. In addition to re-airing the first 10 episodes, the remaining 12 episodes aired from February 24, 2007, through April 8, 2007, although these episodes were made in 2000.