
Barefoot Gen is a Japanese historical manga series by Keiji Nakazawa. Loosely based on Nakazawa's own experiences as a Hiroshima survivor, the series begins in 1945 in and around Hiroshima, Japan, where the six-year-old boy Gen Nakaoka lives with his family. After Hiroshima is destroyed by atomic bombing, Gen and other survivors are left to deal with the aftermath. It ran in several magazines, including Weekly Shōnen Jump, from 1973 to 1987. It was subsequently adapted into three live action film adaptations directed by Tengo Yamada, which were released between 1976 and 1980. Madhouse released two anime films, one in 1983 and one in 1986. In 2007, a live action television drama series adaptation aired in Japan on Fuji TV over two nights, August 10 and 11.

The Beast Player is a Japanese novel series written by Nahoko Uehashi and published by Kodansha between 2006 and 2009. It focuses on a girl who can control the greatest of beasts as she gets involved in a war between two territories of one kingdom.

Blood+ is a Japanese anime television series produced by Production I.G and Aniplex and directed by Junichi Fujisaku. The series was broadcast on MBS and TBS from October 2005 to September 2006. Blood+ is licensed for international distribution in several regions through Sony Pictures' international arm, Sony Pictures Television International (SPTI).

Book Girl is a collection of Japanese light novels by Mizuki Nomura, with illustrations by Miho Takeoka. The series contains 16 volumes: eight cover the original series, four are short story collections, and four are of a side story. The novels were published between April 2006 and April 2011 by Enterbrain under their Famitsu Bunko imprint. Yen Press licensed the light novel series and began releasing it in English in North America in July 2010. There have been four manga adaptations serialized in Square Enix's shōnen Gangan Powered and Gangan Joker, and Kadokawa Shoten's shōjo Beans Ace and Monthly Asuka. An anime film adaptation produced by Production I.G was released in Japanese theaters on May 1, 2010.

Buso Renkin is a Japanese manga series written and illustrated by Nobuhiro Watsuki. It follows Kazuki Muto, who becomes an alchemical warrior in the battle against alchemical monsters known as homunculi. Watsuki envisioned the manga as his last shōnen manga, and then he tried to do as much as he could with that genre. It was serialized in publisher Shueisha's Weekly Shōnen Jump magazine from June 2003 to April 2005. The individual chapters were republished by Shueisha in ten tankōbon. The series has been licensed by Viz Media for North American release.

Chrome Shelled Regios is a Japanese light novel series by Shūsuke Amagi, with illustrations by Miyū. A short story light novel series was serialized in Dragon Magazine. A manga adaptation drawn by Miyū is serialized in the shōnen manga magazine Dragon Age Pure. A second manga adaptation drawn by Nodoka Kiyose is serialized in the shōnen manga magazine Monthly Dragon Age. A third manga adaptation drawn by Watari is serialized in Beans Ace magazine. A four-panel comic strip adaptation drawn by Masumi Futaba started serialization in Monthly Dragon Age on November 8, 2008. A science fiction light novel series titled Legend of Regios is set in the past world of Chrome Shelled Regios series, and published by Fujimi Shobo under its Style-F label. An anime adaptation produced by Zexcs aired on January 11, 2009 to June 20, 2009 and is licensed in North America by Funimation Entertainment.

Da Capo II is a Japanese adult visual novel developed by Circus which was first released on May 26, 2006 for Windows computers. It is a part of the ongoing Da Capo series of games by Circus, and is the direct sequel to Circus' previous title Da Capo released in 2002. Da Capo II is described by Circus as a "ticklish school romance adventure . A fan disc, Da Capo II: Spring Celebration, was released on April 27, 2007 and features springtime stories set after the endings for each of the six Da Capo II heroines. An all-ages consumer port titled Da Capo II: Plus Situation containing additional scenarios was released for the PlayStation 2 in May 2008. The PlayStation 2 version was later ported to PC, titled Da Capo II: Plus Communication and containing the hentai scenes found in the original release, in December 2008.

Death Note Another Note: The Los Angeles BB Murder Cases is a light novel written by Nisio Isin and released on August 1, 2006. The story is a prequel to the manga Death Note, and expands on the briefly-mentioned Los Angeles "BB Murder Cases".

Ef: A Fairy Tale of the Two is a Japanese two-part adult visual novel series by Minori for Windows PCs. The first game in the series, Ef: The First Tale, was released on December 22, 2006, and the second game, Ef: The Latter Tale, was released on May 30, 2008. The opening video for the game was animated by Makoto Shinkai, and a majority of the music was produced by Tenmon, who has worked in the past with Shinkai and Minori. Female character design was by Naru Nanao of Da Capo fame, while male character design was by 2C Galore.

The Familiar of Zero is a Japanese fantasy light novel series written by Noboru Yamaguchi, with illustrations by Eiji Usatsuka. Media Factory published 20 volumes between June 2004 and February 2011. The series was left unfinished due to the author's death in 2013, but was later concluded in two volumes released in February 2016 and February 2017 with a different author, making use of notes left behind by Yamaguchi. The story features several characters from the second year class of a magic academy in a fictional magical world with the main characters being the inept mage Louise and her familiar from Earth, Saito Hiraga.

Gakkō no Kaidan is a Japanese light novel series by Takaaki Kaima with illustrations by Amane Amahuku. The first novel in the series was released on January 30, 2006, and a total of twelve volumes have been published by Enterbrain under their Famitsu Bunko publishing imprint when the series concluded on July 30, 2009. A live action movie adaptation was directed by Hirosaka Sasaki and premiered in Japanese theaters on June 9, 2007. The word kaidan used in the title is homophonic to the word kaidan (怪談), meaning "ghost stories".

Gift is a Japanese adult visual novel developed by Moonstone and released on May 27, 2005, for Windows. The original game was a collaboration project where the company Circus helped to produce it, though Moonstone did the majority of the work involved. Gift is Moonstone's fourth title, and was followed up with an adult fan disc called Gift Rainbow-colored Stories released on January 27, 2006, for Windows. It was later ported to the PlayStation 2 and PlayStation Portable. The gameplay in Gift follows a plot line which offers pre-determined scenarios with courses of interaction, and focuses on the appeal of the five female main characters. The story revolves around Haruhiko Amami, a male high school student living in a town where a rainbow is always seen in the sky.

Gin Tama is a Japanese manga series written and illustrated by Hideaki Sorachi. Set in Edo, which has been conquered by aliens named Amanto, the plot follows life from the point of view of samurai Gintoki Sakata, who works as a freelancer alongside his friends Shinpachi Shimura and Kagura to pay the monthly rent. Sorachi added the science fiction setting to develop characters to his liking after his editor suggested doing a historical series. It was serialized in Shueisha's Weekly Shōnen Jump from December 2003 to September 2018, later in Jump GIGA from December 2018 to February 2019, and finished on the Gin Tama app in May and June 2019.

Giniro no Olynssis , literally translating to Olynssis of Silver, is a Japanese anime television series animated by Toei Animation. It aired in Japan from October 5, 2006 to December 21, 2006. A light novel by Hitomi Amamiya and illustrations by Hisashi Hirai was serialized in the MediaWorks magazine Dengeki Maoh in November 2006.

Happiness! is a Japanese adult visual novel developed by Windmill released on October 21, 2005 for Windows PCs. The game was later ported to the PlayStation 2. An adult fan disc titled Happiness! Re:Lucks was developed by Windmill's sister brand Windmill Oasis and released on July 28, 2006 for Windows. A manga illustrated by Rino Fujii was serialized in Media Factory's Monthly Comic Alive between 2006 and 2007. A series of novels were published by Harvest between 2006 and 2008. A 12-episode anime produced by Artland aired in Japan between October and December 2006, and an original video animation episode followed in January 2007.

Higurashi When They Cry , also known simply as When They Cry prior to 2020, is a Japanese murder mystery dōjin soft visual novel series produced by 07th Expansion that comprises the first two entries of the When They Cry franchise. The series focuses on a group of young friends living in a fictional village and the strange events that occur there in 1983.

Kämpfer is a Japanese light novel series by Toshihiko Tsukiji, with illustrations by Senmu. The series contains 15 volumes published by Media Factory under their MF Bunko J imprint between November 2006 and March 2010. The main series covers 12 volumes, while the remaining three are short story collections. A manga adaptation by Yu Tachibana started serialization in the April 2008 issue of Monthly Comic Alive. A 12-episode anime adaptation aired in Japan between October and December 2009 on TBS, concluded in 2011 with Kämpfer für die Liebe.

Kashimashi: Girl Meets Girl is a Japanese yuri manga series written by Satoru Akahori and illustrated by Yukimaru Katsura. The manga was originally serialized in Dengeki Daioh between the July 2004 and May 2007 issues, and later published in five bound volumes by MediaWorks from January 2005 to May 2007. The story focuses on Hazumu Osaragi, a normal, albeit effeminate high school boy who is killed when an alien spaceship crash lands on him, only to be restored to health as a girl. This results in a same-sex love triangle that Hazumu finds herself in with two of her best female friends.

KimiKiss is a Japanese dating simulation game for the PlayStation 2. Developed by Enterbrain in 2006, KimiKiss has become a media franchise, which includes 5 manga adaptations, a light novel, and an anime television series directed by Ken'ichi Kasai.

The Kouga Ninja Scrolls is a historical fantasy novel about ninja written in 1958–1959 by the Japanese author Futaro Yamada. This is the first volume of the Ninja Scrolls series written by Yamada in 1958–2001. The book has been translated into English by Geoff Sant, and was published by Del Rey in December 2006.

Kujibiki♥Unbalance is a 2006 anime series produced by Ajia-do Animation Works, initially based on the Story within a story Kujibiki Unbalance that originated from Shimoku Kio's manga Genshiken. It is directed by Tsutomu Mizushima and written by Michiko Yokote. It aired in Kids Station in Japan from October 6, 2006 to December 22, 2006.

Ladies versus Butlers! is a Japanese light novel series written by Tsukasa Kōzuki, with accompanying illustrations by Munyū. The series includes 13 novels released between September 2006 and March 2012, published by ASCII Media Works under their Dengeki Bunko imprint. A manga adaptation by the illustrator group Nekoyashiki-Nekomaru was serialized in ASCII Media Works' Dengeki Moeoh magazine between the June 2008 and December 2008 issues. A drama CD based on the novels was released in September 2009. A 12-episode anime adaptation produced by Xebec and directed by Atsushi Ōtsuki aired in Japan between January and March 2010. The anime has been licensed by Media Blasters for release in North America.

Library War is a Japanese light novel series by Hiro Arikawa, with illustrations by Sukumo Adabana. There are four novels in the series, though only the first novel is called Toshokan Sensō; the subsequent novels are named Toshokan Nairan, Toshokan Kiki, and Toshokan Kakumei. The novels were published by MediaWorks between February 2006 and November 2007. Two volumes of a spin-off series entitled Bessatsu Toshokan Sensō have also been published by ASCII Media Works. As of April 2008, the original four novels and volume one of the spin-off series have sold over 1.25 million copies in Japan. The story was inspired from the Statement on Intellectual Freedom in Libraries of the Japan Library Association.

Lovedol ~Lovely Idol~ is the title of a Japanese series which focuses on a group of young girls who are striving to become famous Japanese idols.

Marriage Royale is a series of illustrated Japanese fictional short stories written by Shingo Hifumi and illustrated by Aoi Nishimata and Hiro Suzuhira; both illustrators are from Navel. The short stories ran as part of a reader-participation game in the Japanese bishōjo magazine Dengeki G's Magazine, published by ASCII Media Works, between the January 2006 and May 2011 issues. A manga titled Marriage Royale based on the short stories, illustrated by Koko Natsuki from Lime, was serialized between the April 2007 and January 2011 issues of Dengeki G's Magazine. A second manga titled Marriage Royale: Prism Story illustrated by Junka Morozumi started serialization in Dengeki G's Festival! Comic on October 26, 2009.

Muv-Luv is a Japanese visual novel developed by âge and originally released as an adult game for Windows on February 28, 2003. Consisting of two parts, Muv-Luv Extra and Muv-Luv Unlimited, the gameplay in Muv-Luv follows a linear plot line, which offers pre-determined scenarios and courses of interaction, and focuses on the differing scenarios of the female main characters. Muv-Luv was followed by a sequel, Muv-Luv Alternative, which was released for Windows on April 24, 2006 and follows the storyline of Muv-Luv Unlimited.

My Girlfriend's a Geek is a Japanese light novel series in two volumes by Pentabu based on a popular blog of the same name with 11 million page views. A manga adaptation by Rize Shinba started serialization in 2007 and was published by Enterbrain under their B's LOG Comic imprint. A movie adaption was published in 2009 with My Geeky Girlfriend as the International English title. Both the light novel and manga have been licensed for release by Yen Press.

Nanatsuiro Drops is a Japanese adult visual novel developed by UNiSONSHIFT and released on April 21, 2006 for Windows. The game was later ported to the PlayStation 2 and Nintendo DS. A light novel, written by Tamaki Ichikawa and illustrated by Noizi Ito, was published by Enterbrain in June 2006. Two manga adaptations were published by MediaWorks and later ASCII Media Works. A 12-episode anime produced by Studio Barcelona aired between July and September 2007.

Nursery Rhyme is a Japanese adult visual novel developed by Lump of Sugar and released on November 25, 2005 for Windows. The story follows the life of Shizuma Hasekura, who visits his childhood friend Makina Tomoe and her twin sister, Yukina Tomoe. Nursery Rhyme is set in future, and takes place in the same world of Tayutama: Kiss on my Deity.

The Okami-san series is a collection of Japanese light novels by Masashi Okita, with illustrations by Unaji. The series started with the release of the first volume in August 2006 titled Okami-san & her Seven Companions , and as of January 2011, 12 volumes have been published by ASCII Media Works under their Dengeki Bunko imprint. A manga adaptation by Kurumi Suzushiro started serialization in the April 2010 issue of ASCII Media Works' shōnen manga magazine Dengeki Daioh. A 12-episode anime adaptation by J.C.Staff aired in Japan on AT-X between July 1 and September 16, 2010, and has been licensed and dubbed into English by Funimation Entertainment to be aired on American network television and released to DVD. The English-dubbed version of the anime adaptation was subsequently licensed and distributed by Madman Entertainment and Manga Entertainment to Australia and the United Kingdom, respectively.

Planetarian: The Reverie of a Little Planet is a Japanese post-apocalyptic visual novel developed by Key, a brand of VisualArt's whose previous works include Kanon and Air. It was released over the Internet on November 29, 2004, for Windows, and is rated for all ages. The game was later ported to the PlayStation 2 (PS2), PlayStation Portable and Nintendo Switch, as well as mobile devices. The story centers on a man who comes across a malfunctioning robot in a dead city. The man, known simply as "the junker", stays with this robot for a time and attempts to fix the projector of the planetarium where the story takes place.

Run with the Wind is a 2006 Japanese novel by Shion Miura. The novel has received a manga and a live-action film adaptation, as well as an anime television series adaptation by Production I.G that aired from October 2, 2018 to March 26, 2019.

Shigofumi: Letters from the Departed, titled Shigofumi: Stories of Last Letter in Japan, or simply Shigofumi, is a Japanese anime television series created by Tomorō Yuzawa and produced by Bandai Visual and Genco, which aired in Japan on Chiba TV and other networks between January 6 and March 22, 2008, and contains twelve episodes. An original video animation episodes was included with the final anime DVD volume released on September 26, 2008. A light novel series was originally adapted from the anime's premise set by Tomorō Yuzawa, featuring story composition and illustrations by Ryō Amamiya and Poko, respectively. Four novels were published by MediaWorks under their Dengeki Bunko imprint between October 2006 and March 2008. Despite the novels being produced first, the anime is considered the original work, as stated by Yuzawa. The anime was acquired by Bandai Visual for English language localization. The title Shigofumi comes from the combination of the Japanese words for "after death" , and "letter" , which literally translates to an "after death letter". However, the release was cancelled and Bandai Visual closed its North American branch. Sentai Filmworks picked up the license and released the entire series on DVD in 2010.

Shinkyoku Sōkai Polyphonica (神曲奏界ポリフォニカ), also known as simply Polyphonica, is a Japanese an all-age visual novel created by Ocelot and first released for Windows on April 28, 2006. Aside from the game, multiple series of light novels have been created, and a manga adaptation started in March 2007. An anime adaptation that aired in Japan between April to June 2007. Another anime adaption aired from April to June 2009, and was a prequel of the events in the first anime.

Simoun is a Japanese anime television series created by Shō Aikawa, Yoshizaki Sasa and Gō Mihara. It ran for 26 episodes on TV Tokyo from April 3 to September 25, 2006.

Spice and Wolf is a Japanese light novel series written by Isuna Hasekura, with illustrations by Jū Ayakura. ASCII Media Works has published 22 novels since February 2006 under their Dengeki Bunko imprint. ASCII Media Works reported that as of October 2008, over 2.2 million copies of the first nine novels have been sold in Japan. The series has been called a "unique fantasy" by Mainichi Shimbun due to the plot focusing on economics, trade, and peddling rather than the typical staples of fantasy such as swords and magic. Yen Press licensed the light novels and is releasing them in English in North America. ASCII Media Works has published five volumes of a spin-off light novel series titled Wolf and Parchment since September 2016.

Strawberry Panic! is a series of Japanese illustrated short stories written by Sakurako Kimino, which focus on a group of teenage girls attending three affiliated all-girl schools on Astraea Hill. A common theme throughout the stories is the intimate lesbian relationships between the characters. The original artist was Chitose Maki, who was succeeded by Namuchi Takumi when production of the manga and light novels began.

Strike Witches is a Japanese media mix originally created by Fumikane Shimada via a series of magazine illustration columns. The franchise has since been adapted into several light novel, manga, and anime series and various video games. The series revolves around teenage girls who use machines attached to their legs to do aerial combat. The OVA preview episode was released in January 2007. The televised anime series later aired between July and September 2008. A second season aired between July and September 2010. A film adaptation was released on March 17, 2012 and a three part OVA series was released between September 2014 and May 2015. A third season aired from October to December 2020.

Summer Days is an erotic visual novel developed by 0verflow, released on June 23, 2006, for Microsoft Windows and later ported as a DVD game and for the PlayStation Portable (PSP). It is the second installation of School Days line of series, succeeding the visual novel of the same name and preceding Cross Days. Unlike the previous titles, that exist in the same continuity however, Summer Days is a spin-off of the original story retold from the perspective of Setsuna Kiyoura, a high school student out for summer vacation who finds herself attracted to Makoto Itou, a classmate and fellow patron of a restaurant she eventually comes to work at. The game retains the anime-like presentation familiar to the franchise, requiring little interaction from users, engaging players through a nonlinear plot they are given opportunities to change, and concluding with an ending specific to the choices made during play.

Togainu no Chi is a Japanese BL visual novel created by Nitro+CHiRAL. The plot centers on Akira, a young man who is made to participate in a deadly game called "Igura" in post-apocalyptic Japan in exchange for being freed from prison. His goal is to beat "Il Re", the strongest person in Igura. The game was originally released on PC as Togainu no Chi in 2005, with a PlayStation 2 version titled Togainu no Chi TRUE BLOOD being released on May 29, 2008. A PlayStation Portable version was released on December 23, 2010 under the name of Togainu no Chi True Blood Portable.

Toradora! is a Japanese light novel series by Yuyuko Takemiya, with illustrations by Yasu. The series includes ten novels released between March 10, 2006 and March 10, 2009, published by ASCII Media Works under their Dengeki Bunko imprint. Three volumes of a spin-off light novel series were also created, aptly titled Toradora Spin-off!. A manga adaptation by Zekkyō started serialization in the September 2007 issue of the shōnen manga magazine Dengeki Comic Gao!, published by MediaWorks. The manga ended serialization in Dengeki Comic Gao! with the March 2008 issue, but continued serialization in ASCII Media Works' manga magazine Dengeki Daioh with the May 2008 issue.

xxxHolic is a Japanese manga series written and illustrated by the manga group Clamp. The series, which crosses over with another Clamp work, Tsubasa: Reservoir Chronicle, revolves around Kimihiro Watanuki, a high school student who is disturbed by his ability to see the supernatural, and Yūko Ichihara, a powerful witch who owns a wish-granting shop. When Watanuki asks Ichihara to remove his ability to see spirits, she grants it on the condition that he pay for his wish by working for her. Clamp created xxxHolic to link the supernatural and fantasy series. From 2013 to 2016 they worked on a sequel series xxxHolic: Rei.

Yoake Mae yori Ruriiro na , also known as Crescent Love, is a Japanese adult visual novel developed by August and first released on September 22, 2005 for Windows. It was later ported to the PlayStation 2 and PlayStation Portable. A manga illustrated by Hoehoe Nōmiso was serialized in Dengeki Daioh between the November 2005 and May 2007 issues. A 12-episode anime adaptation titled Yoake Mae yori Ruriiro na: Crescent Love aired in Japan between October and December 2006. The anime is licensed by Sentai Filmworks in North America and was released on June 1, 2010.